Shixiang Sun

Shixiang Sun, Ph.D.

Email

Phone

Location

  • Albert Einstein College of Medicine Michael F. Price Center 1301 Morris Park Avenue 468 Bronx, NY 10461

Professional Interests

  • Bioinformatics and computational biology
  • Genome instability and transcriptional regulation during aging and diseases
  • Single cell analysis
  • Big data integration and curation in databases

Selected Publications

  1. Sun, S., Wang, Y., Maslov, A.Y., Dong, X. & Vijg, J. SomaMutDB: a database of somatic mutations in normal human tissues. Nucleic Acids Res 50, D1100-D1108 (2022).
  2. Huang, Z. et al. Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking. Nat Genet 54, 492-498 (2022).
  3. Sun, S. et al. Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers. J Clin Invest 132(2022).
  4. Brazhnik, K. et al. Single-cell analysis reveals different age-related somatic mutation profiles between stem and differentiated cells in human liver. Sci Adv 6, eaax2659 (2020).
  5. Dong, X. et al. Age-related telomere attrition causes aberrant gene expression in sub-telomeric regions. Aging Cell 20, e13357 (2021).

Full publication list:
https://scholar.google.com/citations?user=w_lZ1PQAAAAJ&hl