Genomics The Genomics Core serves the Einstein scientific community by providing a broad range of services, utilizing current and emerging nucleic acid technologies. Single-cell assays, MPS, Microarrays, real-time PCR, Sanger sequencing and assay automation are available. The Core provides a number of technologies for genotyping DNA from humans or model organisms, varying from SNP (single nucleotide polymorphism) typing to targeted sequencing for variant discovery. Services Access the Services Single Cell Analysis Single Cell (sc) Genomics Assays Single Cell Western analysis Targeted Single Cell DNA-Seq MPS (Next Gen Sequencing) – assays include RNA-seq, ChIP-seq, ATAC-seq, MethylC-seq, HELP-tagging and MAD-seq Gene Expression Microarrays – Affymetrix Transcriptome arrays (alt-splice detection), cost effective 3’ arrays, miRNA, fast turnaround and free data analysis software Genotyping and Copy Number Variation (CNV) Microarrays Single Nucleotide Polymorphism (SNP) and Mutation Analysis – Affymetrix SNP6 and CytoScan Cytosine Methylation Analysis Sanger Sequencing – fast service and one on one troubleshooting Cell Line Authentication (CLA) – ensure your cell lines meet current guidelines Microsatellite Instability Analysis (MSI) RNA/DNA Quality Analysis – Agilent Bioanalyzer and Caliper GX qPCR – gene expression, Taqman SNPs, 384-well, 96-well and array card formats Liquid Handling Automation – high throughput PCR, plate replication, dilutions Related Shared Facilities Biostatistics Computational GenomicsEpigenomics Center Affiliations Montefiore Einstein Comprehensive Cancer Center Selected Publications Deletion size analysis of 1680 22q11.2DS subjects identifies a new... Global, integrated analysis of methylomes and transcriptomes from laser... Mammary-stem-cell-based somatic mouse models reveal breast cancer... Minimal reduction of PU.1 is sufficient to induce a preleukemic... Location and Contacts Genomics Ullmann 1203 Bernice Morrow, Ph.D.Scientific Director718-678-1121bernice.morrow@einsteinmed.eduDavid ReynoldsOperations Director929-246-6735david.reynolds@einsteinmed.edu
