X-Ray Crystallography The X-Ray Crystallography Facility provides the expertise needed to obtain high-resolution structures by X-ray diffraction, including crystallization, primary phasing, structure refinement and data interpretation. To rapidly accomplish these tasks, the facility is equipped with state-of-the-art robotics for screening sub-microliter volumes of protein and RT-PCR based stability tests to enhance crystallization efforts. All data are collected using synchrotron radiation using our rapid and sustained access to beamlines at Brookhaven National Labs. These structural technologies are complemented by cryo-electron microscopy, electron paramagnetic resonance, a wide range of vibrational spectroscopies, novel macromolecular footprinting approaches and computational biology. A full list of services is available on the facility website. Services Support for solving structures using X-ray crystallography: Data collection, processing and interpretation Structure solution Structure analysis Related Shared Facilities Structural NMR Center Affiliations Montefiore Einstein Comprehensive Cancer Center Selected Publications Biochemistry, 2008 May 6;47(18):5111-26 Nature Structural and Molecular Biology, 2008 Jan;15(1):103-5 Proceedings of the Natl Academy of Sciences USA, 2008 Jan 15;105(2):635-40 Proceedings of the Natl Academy of Sciences USA,2008 Jul 29;105(30):10483-8 Location and Contacts X-Ray Crystallography Ullmann 409 Steven C. Almo, Ph.D.Scientific Director718-430-2746steve.almo@einsteinmed.eduJeffrey B. Bonanno, Ph.D.Associate Director718.430.2743jeffrey.bonanno@einsteinmed.edu
