Irina Murakhovskaya

Submitted by Anonymous (not verified) on
Full Name
Irina Murakhovskaya
Profile Image URL
https://documentapi-fargate-documentbucket-15qi4tpdvnhlz.s3.amazonaws.com/218/4f602dc0-4e1f-11ee-8db1-bb4c384b05c4.jpg
Type
Provider
Faculty
First Name
Irina
Last Name
Murakhovskaya
NPI
1235180464
Faculty ID
13953
CMO Specialties
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-oncology
einstein-dept-medicine
Gender
Female
Email
imurakho@montefiore.org
Phone
718-920-4137
Titles
Type
Academic
Department
Department of Oncology
Rank
Associate Professor
Division
Hematology
Type
Academic
Department
Department of Medicine
Department Link
Rank
Associate Professor
Division
Oncology & Hematology
Type
Administrative
Title
Chief, Division of Hematology
Tags
me-patientcare-hematology
Locations
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84544 40.84518)
Address Line 1
1621 Eastchester Road
City
Bronx
State
NY
Zip
10461-2301
Location Title
Montefiore Medical Group-Comprehensive Family Care Center (CFCC)
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84563 40.84596)
Address Line 1
1575 Blondell Avenue
City
Bronx
State
NY
Zip
10461-2601
Location Title
Montefiore Medical Park at 1575 Blondell
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.88133 40.88109)
Address Line 1
3444 Kossuth Avenue
City
Bronx
State
NY
Zip
10467-2241
Location Title
Montefiore Medical Group-Family Care Center (FCC)
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84475 40.84623)
Address Line 1
1695 Eastchester Road
City
Bronx
State
NY
Zip
10461
Location Title
Montefiore Medical Park at Eastchester
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.88263 40.87994)
Address Line 1
60 East 208th Street
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore at 60 East 208th Street
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8782381 40.8799784)
Address Line 1
Montefiore Medical Center
Address Line 3
3411 Wayne Avenue
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore Medical Center
Education and Trainings
Education Type Label
Medical Education
Education Institution
Albert Einstein College of Medicine
Education Type Label
Fellowship
Education Institution
Montefiore Medical Center-AECOM
Professional Interests

<p>Dr. Irina Murakhovskaya is an Assistant Professor of Medicine (Hematology). She completed a medical degree at Albert Einstein College of Medicine and residency and fellowship training at Montefiore Health System. Her clinical interests focus on monoclonal gammopathy, low-grade lymphoma, and hematologic issues in pregnancy.</p>
<p>Dr. Murakhovskaya is currently chairman of the fellowship Clinical Competency Committee and assistant course director for the Albert Einstein of Medicine Hematology Course.&nbsp;</p>

CHAM Provider
Off
Professional Title
M.D.
EMR ID
4308
Is Open Scheduling
Off

Katharine A. McNeill

Submitted by Anonymous (not verified) on
Full Name
Katharine A. McNeill
Profile Image URL
https://documentapi-fargate-documentbucket-15qi4tpdvnhlz.s3.amazonaws.com/218/507c4f00-3934-11ed-9b41-f32856b0701a.jpg
Type
Provider
Faculty
First Name
Katharine
Last Name
McNeill
NPI
1598995730
Faculty ID
15494
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-neurology
einstein-dept-oncology
einstein-dept-radiation-oncology
Gender
Female
Email
kmcneill@montefiore.org
Phone
718-920-5062
Titles
Type
Academic
Department
The Saul R. Korey Department of Neurology
Department Link
Rank
Assistant Professor
Tags
me-patientcare-neurology-about-team
me-neuroscience-braintumorcenter
me-patientcare-cancer-clinical-neuro-oncology
Type
Academic
Department
Department of Oncology
Rank
Assistant Professor
Tags
me-neuroscience-skullcranialbasecenterteam
me-patientcare-cancer-clinical-aids-malignancies
Division
Medical Oncology
Type
Academic
Department
Department of Radiation Oncology
Rank
Assistant Professor
Type
Administrative
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.88072 40.88002)
Address Line 1
111 East 210th Street
City
Bronx
State
NY
Zip
10461-2401
Location Title
Montefiore Medical Center
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84607 40.84531)
Address Line 1
1521 jarrett Place
City
Bronx
State
NY
Zip
10461-2606
Location Title
Montefiore M-E Center for Cancer Care
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8798833 40.8799447)
Building
Hofheimer Main
Room
100
Address Line 1
Montefiore Medical Center
Address Line 3
111 East 210th Street
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore Medical Center
Education and Trainings
Education Type Label
Medical Education
Education Institution
University of Maryland School of Medicine
Education Type Label
Fellowship
Education Institution
National Institutes of Health
Education Type Label
Residency
Education Institution
Beth Israel Deaconess Medical Center
CHAM Provider
Off
Professional Title
M.D.
EMR ID
1542
Is Open Scheduling
Off

Ioannis Mantzaris

Submitted by Anonymous (not verified) on
Full Name
Ioannis Mantzaris
Profile Image URL
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Type
Provider
Faculty
First Name
Ioannis
Last Name
Mantzaris
NPI
1871865519
Faculty ID
14586
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-oncology
einstein-dept-medicine
Gender
Male
Email
imantzar@montefiore.org
Phone
718-920-4826
Titles
Type
Academic
Department
Department of Oncology
Rank
Associate Professor
Tags
me-patientcare-cancer-clinical-aids-malignancies
me-patientcare-cancer-clinical-blood-bone-marrow
me-patientcare-cancer-research-therapeutics
Division
Medical Oncology
Type
Academic
Department
Department of Medicine
Department Link
Rank
Associate Professor
Division
Oncology & Hematology
Type
Administrative
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.88072 40.88002)
Address Line 1
111 East 210th Street
City
Bronx
State
NY
Zip
10461-2401
Location Title
Montefiore Medical Center
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8798833 40.8799447)
Building
Hofheimer Main
Room
100
Address Line 1
Montefiore Medical Center
Address Line 3
111 East 210th Street
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore Medical Center
Education and Trainings
Education Type Label
Medical Education
Education Institution
University of Athens Medical School
Education Type Label
Fellowship
Education Institution
Montefiore Medical Center
Education Type Label
Residency
Education Institution
Jacobi Medical Center
Education Type Label
Residency
Education Institution
General Hospital of Trikala
Education Type Label
Residency
Education Institution
Agios Savvas Anticancer-Oncology Hospital Athens
CHAM Provider
Off
Professional Title
M.D.
M.S.
EMR ID
57027
Is Open Scheduling
Off

Della F. Makower

Submitted by Anonymous (not verified) on
Full Name
Della F. Makower
Profile Image URL
https://assets.montefioreeinstein.org/profiles/images/physphoto/Makower_Della_MD_420x504.jpg
Type
Provider
Faculty
First Name
Della
Last Name
Makower
NPI
1578559910
Faculty ID
6729
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-oncology
einstein-dept-medicine
Gender
Female
Email
dmakower@montefiore.org
Phone
718-405-8405
Titles
Type
Academic
Department
Department of Oncology
Rank
Associate Professor
Tags
me-patientcare-cancer-research-therapeutics
me-patientcare-cancer-clinical-breast
me-patientcare-breastcarecenter
Division
Medical Oncology
Type
Academic
Department
Department of Medicine
Department Link
Rank
Associate Professor
Division
Oncology & Hematology
Type
Administrative
Locations
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84607 40.84531)
Address Line 1
1521 jarrett Place
City
Bronx
State
NY
Zip
10461-2606
Location Title
Montefiore M-E Center for Cancer Care
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84563 40.84596)
Address Line 1
1575 Blondell Avenue
City
Bronx
State
NY
Zip
10461-2601
Location Title
Montefiore Medical Park at 1575 Blondell
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84475 40.84623)
Address Line 1
1695 Eastchester Road
City
Bronx
State
NY
Zip
10461
Location Title
Montefiore Medical Park at Eastchester
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.845166 40.8462736)
Address Line 1
Montefiore Medical Park
Address Line 3
1695 Eastchester Road
City
Bronx
State
NY
Zip
10461
Location Title
Montefiore Medical Park
Education and Trainings
Education Type Label
Medical Education
Education Institution
New York University
Education Type Label
Fellowship
Education Institution
Montefiore Medical Center
Education Type Label
Residency
Education Institution
New York University Medical Center
Professional Interests

<p>My research is focused on breast cancer management, and on care delivery and support for breast cancer patients.&nbsp;</p>

CHAM Provider
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Professional Title
M.D.
EMR ID
3965
Is Open Scheduling
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Kenneth G. Liu

Submitted by Anonymous (not verified) on
Full Name
Kenneth G. Liu
Profile Image URL
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Type
Provider
Faculty
First Name
Kenneth
Last Name
Liu
NPI
1174840888
Faculty ID
15135
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-oncology
einstein-dept-medicine
Gender
Male
Email
kliu@montefiore.org
Phone
718-405-1700
Titles
Type
Academic
Department
Department of Oncology
Rank
Assistant Professor
Division
Medical Oncology
Type
Academic
Department
Department of Medicine
Department Link
Rank
Assistant Professor
Division
Oncology & Hematology
Type
Administrative
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.88263 40.87994)
Address Line 1
60 East 208th Street
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore at 60 East 208th Street
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8822305 40.8791652)
Address Line 1
Montefiore Medical Center
Address Line 3
60 East 208th Street
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore Medical Center
Education and Trainings
Education Type Label
Medical Education
Education Institution
University of Cincinnati College of Medicine
Education Type Label
Fellowship
Education Institution
Montefiore Medical Center
Education Type Label
Residency
Education Institution
Harbor UCLA Medical Center
CHAM Provider
Off
Professional Title
M.D.
EMR ID
57009
Is Open Scheduling
Off

Noah Kornblum

Submitted by Anonymous (not verified) on
Full Name
Noah Kornblum
Profile Image URL
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Type
Provider
Faculty
First Name
Noah
Last Name
Kornblum
NPI
1053461517
Faculty ID
13153
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-oncology
einstein-dept-medicine
Languages
Spanish
Gender
Male
Email
nkornblu@montefiore.org
Phone
718-405-8404
Titles
Type
Academic
Department
Department of Oncology
Rank
Associate Professor
Division
Medical Oncology
Type
Academic
Department
Department of Medicine
Department Link
Rank
Associate Professor
Division
Oncology & Hematology
Type
Administrative
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84475 40.84623)
Address Line 1
1695 Eastchester Road
City
Bronx
State
NY
Zip
10461
Location Title
Montefiore Medical Park at Eastchester
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.845166 40.8462736)
Address Line 1
Montefiore Medical Park
Address Line 3
1695 Eastchester Road
City
Bronx
State
NY
Zip
10461
Location Title
Montefiore Medical Park
Education and Trainings
Education Type Label
Medical Education
Education Institution
Sackler School of Medicine, New York
Education Type Label
Fellowship
Education Institution
Montefiore Medical Center
Education Type Label
Residency
Education Institution
University of California Los Angeles Medical
CHAM Provider
Off
Professional Title
M.D.
Clinical Focus

Non-Hodgkin Lymphoma&nbsp;<br /><br />

EMR ID
4258
Is Open Scheduling
Off

Rasim A. Gucalp

Submitted by Anonymous (not verified) on
Full Name
Rasim A. Gucalp
Profile Image URL
https://documentapi-fargate-documentbucket-15qi4tpdvnhlz.s3.amazonaws.com/218/e88015b0-09f1-11ed-be8f-e58d49e7c7df.jpg
Type
Provider
Faculty
First Name
Rasim
Last Name
Gucalp
NPI
1295815785
Faculty ID
4777
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-oncology
einstein-dept-medicine
Languages
Spanish
Gender
Male
Email
rgucalp@montefiore.org
Phone
718-405-8536
Titles
Type
Academic
Department
Department of Oncology
Rank
Professor
Division
Medical Oncology
Type
Academic
Department
Department of Medicine
Department Link
Rank
Professor
Division
Oncology & Hematology
Type
Administrative
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84475 40.84623)
Address Line 1
1695 Eastchester Road
City
Bronx
State
NY
Zip
10461
Location Title
Montefiore Medical Park at Eastchester
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84607 40.84531)
Address Line 1
1521 jarrett Place
City
Bronx
State
NY
Zip
10461-2606
Location Title
Montefiore M-E Center for Cancer Care
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.845166 40.8462736)
Address Line 1
Montefiore Medical Park
Address Line 3
1695 Eastchester Road
City
Bronx
State
NY
Zip
10461
Location Title
Montefiore Medical Park
Education and Trainings
Education Type Label
Medical Education
Education Institution
Hacettepe Universitesi Tip Fakultesi
Education Type Label
Fellowship
Education Institution
Montefiore Medical Center
Education Type Label
Fellowship
Education Institution
Hacettepe Universitesi Faculty of Medicine
Education Type Label
Residency
Education Institution
SUNY Downstate
Professional Interests

<p>Dr. Rasim Gucalp&rsquo;s research interests include novel therapies in lung cancer as well as supportive care in cancer patients. He is actively involved in the multidisciplinary care of patients with lung cancer and central nervous system tumors. He is a member of several Montefiore Medical Center/Albert Einstein College of Medicine committees including the institutional tumor board, faculty senate, Pharmacy and Therapeutic Committee, and COGME.</p>
<p>A native of Turkey, Dr. Gucalp received his medical degree at Hacettepe University School of Medicine in Ankara, Turkey. After completing his medical residency at Downstate Medical Center in Brooklyn, he came to Montefiore Medical Center to complete his oncology fellowship. He is the director of the Hematology/Oncology Fellowship Program at Montefiore, and serves as a professor of Clinical Medicine at Albert Einstein College of Medicine.&nbsp;</p>

CHAM Provider
Off
Professional Title
M.D.
EMR ID
3765
Is Open Scheduling
Off

Kira Gritsman

Submitted by Anonymous (not verified) on
Full Name
Kira Gritsman
Profile Image URL
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Type
Provider
Faculty
First Name
Kira
Last Name
Gritsman
NPI
1174598148
Faculty ID
14128
Clinical Terms
Employment Status
part-time
Patient Type
Adult
Department
einstein-dept-oncology
einstein-dept-medicine
einstein-dept-cell-biology
Gender
Female
Email
kira.gritsman@einsteinmed.edu
Phone
929-246-6707
Titles
Type
Academic
Department
Department of Oncology
Rank
Associate Professor
Division
Medical Oncology
Type
Academic
Department
Department of Medicine
Department Link
Rank
Associate Professor
Division
Oncology & Hematology
Type
Academic
Department
Department of Cell Biology
Department Link
Rank
Associate Professor
Type
Clinical
Title
Assistant Director of Correlative Clinical Research
Type
Administrative
Title
Co-Leader, Montefiore Einstein Comprehensive Cancer Center, Stem Cell & Cancer Biology Program
Tags
me-patientcare-cancer-clinical-aids-malignancies
me-patientcare-cancer-research-stem-cell-cancer-biology
Type
Administrative
Title
Betty and Sheldon Feinberg Senior Faculty Scholar in Cancer Research
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.88072 40.88002)
Address Line 1
111 East 210th Street
City
Bronx
State
NY
Zip
10461-2401
Location Title
Montefiore Medical Center
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8459022 40.8504961)
Building
Chanin Building
Room
410A
Address Line 1
Albert Einstein College of Medicine
Address Line 2
Jack and Pearl Resnick Campus
Address Line 3
1300 Morris Park Avenue
City
Bronx
State
NY
Zip
10461
Location Title
Albert Einstein College of Medicine
Education and Trainings
Education Type Label
Medical Education
Education Institution
New York University School of Medicine
Education Type Label
Medical Education
Education Institution
New York University School of Medicine
Education Type Label
Medical Education
Education Institution
New York University School of Medicine
Education Type Label
Fellowship
Education Institution
Dana Farber Cancer Institute
Education Type Label
Fellowship
Education Institution
Dana-Farber Cancer Institute
Education Type Label
Residency
Education Institution
Columbia University Medical Center
Professional Interests

<p><strong>The Roles of Signaling Pathways in Adult Blood Development and Leukemia</strong></p>
<p><span style="font-size: 10.5pt; font-family: Verdana, sans-serif;">The Gritsman lab studies the signal transduction pathways that affect the early fate decisions of adult hematopoietic stem cells (HSCs) as they progress from an undifferentiated multipotent state to the generation of differentiated blood cells.&nbsp; When these early fate decisions go awry, this can lead to the formation of leukemia-initiating cells. We are interested in</span><span style="font-size: 10.5pt; font-family: Verdana, sans-serif;">&nbsp;how signaling pathways affect the self-renewal and differentiation of HSCs and malignant or pre-malignant stem cells in myeloid malignancies, such as acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and myeloproliferative neoplasms (MPN).</span></p>
<p><strong>Roles of the PI3 kinase isoforms in adult blood development</strong></p>
<p>PI3 kinase (PI3K) is a lipid kinase that is important for the regulation of metabolism, the cell cycle, apoptosis, and protein synthesis. &nbsp;In hematopoietic cells, there are four isoforms of the catalytic subunit of PI3K, each encoded by a separate gene. &nbsp;Emerging evidence suggests that these isoforms have unique functions in normal and cancer cells, but may substitute for each other in some contexts.&nbsp; We have generated a series of mouse knockout models that allow us to study the roles of each of these isoforms individually in adult hematopoiesis.&nbsp; For example, we have found that the p110alpha isoform is most important for red cell development, but is not required in normal blood stem cells. We have now also generated compound knockout mice to determine the redundant roles of the PI3K isoforms in blood development. &nbsp;We recently reported that PI3K isoforms play important redundant roles during the hematopoietic stress response, such as after chemotherapy. However, deletion of all 3 Class IA PI3K isoforms leads to a phenotype with impaired HSC differentiation, resembling myelodysplastic syndrome (MDS). We are studying how deletion of PI3K will impact normal HSC function, including self-renewal, proliferation, and differentiation along different blood lineages by affecting processes such as autophagy and epigenetic regulation in HSCs.</p>
<p><strong>Roles of the PI3 kinase isoforms in leukemia</strong></p>
<p>Acute myeloid leukemia (AML) is a genetically diverse disease, but activation of the PI3K pathway has been reported in up to 80% of cases.&nbsp; A subset of AML cell lines and AML patient samples respond to PI3K pathway inhibitors, but it is unclear how patients should be selected for potential response to these inhibitors. &nbsp;We found that RAS-mutated myeloid leukemias are particularly dependent on the p110alpha isoform of PI3K, and that pharmacologic inhibition of p110alpha can be used to treat both RAS-mutated cell lines and RAS-mutated leukemia in mice. Furthermore, we use cell lines, patient samples, and mouse models of leukemia to investigate the mechanisms of resistance to PI3K inhibition, with the goal of identifying new drug targets and designing new combination treatments for leukemia that incorporate PI3K inhibitors.</p>
<p><strong>RON Kinase in Myeloproliferative Neoplasms</strong></p>
<p>The myeloproliferative neoplasms (MPNs) are a group of diseases that are caused by kinase mutations in HSCs, which lead to uncontrolled proliferation of myeloid cells. The Philadelphia chromosome-negative MPNs are characterized by mutations in the JAK/STAT signaling pathway, and respond to JAK inhibitors, but resistance often develops. We recently discovered that the receptor Tyrosine kinase RON can physically interact with JAK2 in MPN cells, leading to potentiation of JAK/STAT signaling in resistant cells. Furthermore, we found that pharmacologic or genetic inactivation of RON can inhibit proliferation of MPN cells and re-sensitize resistant cells to JAK inhibitors.</p>
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt; font-size: medium; font-family: 'Times New Roman', serif;"><strong><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: #201f1e;">Member of the Cancer Dormancy and Tumor Microenvironment Institute&nbsp;</span></strong></p>
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt; font-size: medium; font-family: 'Times New Roman', serif;">&nbsp;</p>
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt; font-size: medium; font-family: 'Times New Roman', serif;"><span style="font-size: 10.5pt; font-family: Verdana, sans-serif;">&nbsp;</span><span style="font-size: 10.5pt; font-family: Verdana, sans-serif;">The Gritsman lab&rsquo;s research interests include the contributions of signaling pathways to leukemic and pre-leukemic stem cell dormancy in minimal residual disease, which includes mechanisms of immune evasion. Furthermore, the Gritsman lab is interested in the roles of inflammatory signaling pathways and of the local microenvironment in bone marrow fibrosis, and in the evolution of myeloid neoplasms from the pre-malignant to malignant state. Our major goals are to identify opportunities for therapeutic targeting to prevent the transition from the pre-leukemic state to leukemia, or to eliminate minimal residual disease to prevent relapse.</span></p>

Research Areas
roles of signaling pathways in hematopoietic stem cell self-renewal and differentiation, leukemic stem cells, targeting signaling pathways in hematologic malignancies
CHAM Provider
Off
Professional Title
M.D.
Ph.D.
Selected Publications

<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><a name="_GoBack"></a><span style="font-size: 11pt; font-family: Arial, sans-serif;">Ames, K.,&nbsp;<sup>&nbsp;</sup>Kaur,<sup>&nbsp;</sup>I., Shi, Y., Tong, M., Sinclair, T., Hemmati, S., Glushakow-Smith, S.G., Tein,&nbsp;&nbsp;E., Gurska, L., Steidl, U., Dubin, R., Shan, J., Montagna, C., Pradhan, K., Verma, A., and&nbsp;<strong><u>Gritsman, K.</u></strong>, Deletion of PI3-Kinase Promotes Myelodysplasia Through Dysregulation of Autophagy in Hematopoietic Stem Cells,&nbsp;<strong><em>Science Advances</em></strong><em>&nbsp;2023.&nbsp;</em>doi:&nbsp;<a href="https://nam04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fdoi.o…; target="_blank" rel="noopener"><span style="color: black; text-decoration: none;">10.1126/sciadv.ade8222</span></a><u>,&nbsp;</u>PMID:&nbsp;36812307</span></p>
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><span style="font-size: 11pt; font-family: Arial, sans-serif;">Folgado Marco, V., Ames, K., Chuen, J.,&nbsp;<strong><u>Gritsman, K.</u></strong>&nbsp;&amp; Baker, N.,&nbsp;Haploinsufficiency of the essential gene&nbsp;<em>RpS12</em>&nbsp;causes defects in erythropoiesis and hematopoietic stem cell maintenance,&nbsp;<em>&nbsp;<strong>eLife</strong>&nbsp;</em>2023&nbsp;Jun 5;12:e69322. doi: 10.7554/eLife.69322.&nbsp;PMID:&nbsp;37272618</span></p>
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><span style="font-size: 11pt; font-family: Arial, sans-serif;">Gurska, L.M., Okabe, R., Schurer, A., Tong, M.M., Soto, M., Choi, D., Ames, K., Glushakow-Smith, S., Montoya, A., Tein, E., Miles, L.A., Cheng, H., Hankey-Giblin, P., Levine, R.L., Goel, S., Halmos, B., and&nbsp;<strong><u>Gritsman, K.</u></strong>&nbsp;Crizotinib has Preclinical Efficacy in Philadelphia-negative Myeloproliferative Neoplasms,&nbsp;<strong><em>Clinical Cancer Research</em></strong>&nbsp;2022&nbsp;Dec 20:CCR-22-1763. doi: 10.1158/1078-0432.CCR-22-1763. PMID:&nbsp;36537918</span></p>
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><span style="font-size: 11pt; font-family: Arial, sans-serif;">Gurska, L., Ames, K., and&nbsp;<strong><u>Gritsman, K</u></strong>, Signaling Pathways in Leukemic Stem Cells,&nbsp;</span><span style="font-size: 11pt; font-family: Arial, sans-serif; color: #333333; letter-spacing: 0.2pt; background-color: #fcfcfc;">In: Zhang H., Li S. (eds) Leukemia Stem Cells in Hematologic Malignancies.&nbsp;<strong>Advances in Experimental Medicine and Biology</strong>, vol 1143. Springer, Singapore</span><span style="font-size: 11pt; font-family: Arial, sans-serif;">, July 24, 2019, doi:&nbsp;<a href="https://doi.org/10.1007/978-981-13-7342-8_1"><span style="color: black; letter-spacing: 0.2pt; background-color: #fcfcfc; text-decoration: none;">https://doi.org/10.1007/978-981-13-7342-8_1</span></a><span style="letter-spacing: 0.2pt; background-color: #fcfcfc;">;&nbsp;</span>PMID:&nbsp;31338813, PMCID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7249489/&quot; target="_blank" rel="noopener"><span style="color: black; text-decoration: none;">PMC7249489</span></a></span></p>
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><span style="font-size: 11pt; font-family: Arial, sans-serif;">Hemmati, S., Sinclair, T., Tong, M., Bartholdy, B., Okabe, R.O., Ames, K., Ostrodka, L., Haque, T., Kaur, I., Mills, T. S., Agarwal, A., Pietras, E.M., Zhao, J.J., Roberts, T.M., and&nbsp;<strong><u>Gritsman, K.</u></strong>, PI3 kinase alpha and delta promote hematopoietic stem cell activation,&nbsp;<strong><em>JCI Insight&nbsp;</em></strong>2019&nbsp;doi.org/10.1172/jci.insight.125832</span></p>
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><span style="font-size: 11pt; font-family: Arial, sans-serif;">Mitchell, K., Barreyro, L., Todorova, T., Taylor, S., Antony-Debre, I., Narayanagari, S., Carvajal, L., Leite, J., Piperdi, Z., Pendurti, G., Mantzaris, I., Paietta, E., Verma, A.,&nbsp;<strong><u>Gritsman, K.,&nbsp;</u></strong>and Steidl, U. IL1RAP potentiates multiple oncogenic signaling pathways in AML,&nbsp;<strong><em>Journal of&nbsp;Experimental Medicine</em></strong><em>.&nbsp;</em>2018 May 17. doi: 10.1084/jem.20180147,&nbsp;PMID: 29773641</span></p>
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><span style="font-size: 11pt; font-family: Arial, sans-serif;">Hemmati, S., Haque, T., and&nbsp;<strong><u>Gritsman, K</u>,&nbsp;</strong>Inflammatory Signaling Pathways in Pre-leukemic and Leukemic Stem Cells,&nbsp;<strong><em>Frontiers in Oncology</em></strong><em>&nbsp;</em>2017 Nov 13;7:265. doi: 10.3389/fonc.2017.00265</span></p>
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><span style="font-size: 11pt; font-family: Arial, sans-serif;">Bhagat, T.D., Chen, S., Bartenstein, M., Barlowe, A.T., Von Ahrens, D., Choudhary, G.S., Tivnan, P., Amin, E., Marcondes, M., Sanders, M.A., Hoogenboezem, R.M., Kambhampati, S., Ramanchandra, N., Mantzaris, I., Sukrithan, V., Laurence, R., Lopez, R. Bhagat, P., Giricz, O., Sohal, D., Wickrema, A., Yeung, C.,&nbsp;<strong><u>Gritsman, K.,</u></strong>&nbsp;Aplan, P., Hochedlinger, K., Yu, Y., Pradhan, K., Zhang, J., Greally, J.M., Mukherjee, S., Pellagatti, A., Boultwood, J., Will, B., Steidl, U., Raaijmakers, M.H.G.P., Deeg, H.J., Kharas, M.G. and Verma, A. Epigenetically Aberrant Stroma in MDS Propagates Disease Via Wnt/b-Catenin Activation, 2017&nbsp;<strong><em>Cancer Research</em></strong>&nbsp;2017 Jul 6. pii: canres.0282.2017. doi: 10.1158/0008-5472</span></p>
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><span style="font-size: 11pt; font-family: Arial, sans-serif;">Yuzugullu, H., Baitsch, L., Von, T., Steiner, A., Tong, H., Ni, J., Clayton, L., Bronson, R., Roberts, T.,&nbsp;<strong><u>Gritsman, K</u></strong><u>.</u>, and Zhao, J.J. A p110b-Rac signaling loop mediates Pten-loss-induced perturbation of hematopoiesis and leukemogenesis.&nbsp;<strong><em>Nature Communication</em></strong><em>s&nbsp;</em>October 7,2015, doi:10.1038/NCOMMS9501</span></p>
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><span style="font-size: 11pt; font-family: Arial, sans-serif;">Yoda, A., Adelmant, G., Tamburini, J., Chapuy, B., Shindoh, N., Yoda, Y., Weigert, O., Kopp, N., Wu, S-C., Kim, S., Liu, H., Tivey, T., Christie, A.L.,&nbsp;<strong><u>Gritsman, K.</u></strong>,&nbsp; Gotlib, J., Deininger, M., Turley, S., Tyner, J., Marto, J., Weinstock, D.M., and Lane, A.A. Mutations in G-protein beta subunits promote transformation and kinase inhibitor resistance&nbsp;<strong><em>Nature Medicine</em></strong><em>&nbsp;</em>2015 (1):71-5.</span></p>
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><strong><u><span style="font-size: 11pt; font-family: Arial, sans-serif;">Gritsman, K</span></u></strong><strong><span style="font-size: 11pt; font-family: Arial, sans-serif;">.</span></strong><span style="font-size: 11pt; font-family: Arial, sans-serif;">, Yuzugullu, H., Von, T., Yan, H., Clayton, L., Fritsch, C., Maira, S.-M., Hollingworth, G., Choi, C., Khandan, T., Paktinat, M., Okabe, R.O., Roberts, T.M., and Zhao, J.J. &nbsp;Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110alpha<strong>.&nbsp;<em>Journal of Clinical Investigation&nbsp;</em></strong>2014;124(4):1794&ndash;1809.&nbsp;http://www.jci.org/articles/view/69927</span></p&gt;
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><span style="font-size: 11pt; font-family: Arial, sans-serif;">Kharas, M.G. and&nbsp;<strong><u>Gritsman, K</u></strong>. Akt: A Double-Edged Sword for Hematopoietic Stem Cells.&nbsp;<strong><em>Cell Cycle</em>&nbsp;</strong>2010; Vol 9; Issue 7</span></p>
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<p class="MsoNormal" style="margin: 0in; font-size: medium; font-family: Calibri, sans-serif;"><span style="font-size: 11pt; font-family: Arial, sans-serif;">Kharas, M.G., Okabe, R., Ganis, J.J., Gozo,M., Khandan,T., Paktinat, M., Gilliland, D.G., and&nbsp;<strong><u>Gritsman, K</u>.</strong>&nbsp;Constitutively Active AKT Depletes Hematopoietic Stem Cells and Induces Leukemia in Mice.&nbsp;<strong><em>Blood&nbsp;</em></strong>2010; 115(7): 140615&nbsp;http://www.bloodjournal.org/content/115/7/1406</span></p&gt;
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EMR ID
73180
Is Open Scheduling
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Mendel Goldfinger

Submitted by Anonymous (not verified) on
Full Name
Mendel Goldfinger
Profile Image URL
https://documentapi-fargate-documentbucket-15qi4tpdvnhlz.s3.amazonaws.com/218/8c254020-35ce-11ed-8123-8ffce84a9f6a.jpg
Type
Provider
Faculty
First Name
Mendel
Last Name
Goldfinger
NPI
1801174792
Faculty ID
16256
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-oncology
einstein-dept-medicine
Gender
Male
Email
mgoldfin@montefiore.org
Phone
718-920-4826
Titles
Type
Academic
Department
Department of Oncology
Rank
Associate Professor
Tags
me-patientcare-cancer-research-immunotherapy
Division
Medical Oncology
Type
Academic
Department
Department of Medicine
Department Link
Rank
Associate Professor
Division
Oncology & Hematology
Type
Administrative
Locations
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84475 40.84623)
Address Line 1
1695 Eastchester Road
City
Bronx
State
NY
Zip
10461
Location Title
Montefiore Medical Park at Eastchester
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.88072 40.88002)
Address Line 1
111 East 210th Street
City
Bronx
State
NY
Zip
10461-2401
Location Title
Montefiore Medical Center
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8798833 40.8799447)
Building
Hofheimer Main
Room
100
Address Line 1
Montefiore Medical Center
Address Line 3
111 East 210th Street
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore Medical Center
Education and Trainings
Education Type Label
Medical Education
Education Institution
State University of NY at Buffalo School of Medicine
Education Type Label
Fellowship
Education Institution
Robert Wood Johnson University Hospital
Education Type Label
Residency
Education Institution
Montefiore Medical Center
Professional Interests

<p>Dr. William Osler famously said, &ldquo;The good physician treats the disease; the great physician treats the patient who has the disease.&rdquo; I am a strong believer in individualizing treatment plans unique to each patient based on understanding the patient as a whole and the specifics of their disease. I am committed to each patient&rsquo;s care and work hard to ensure that every single patient has the most positive clinical outcome.</p>
<p>I primarily treat people with hematologic malignancies such as Lymphoma, Multiple Myeloma, Leukemia and Bone Marrow diseases. I have a special interest in Chimeric Antigen Receptor T-cell Therapy (CAR T-cell), stem cell transplantation and the use of antibodies to fight cancer. My research focus is in developing novel cellular immunotherapies to target cancer cell antigens. I work with colleagues in our basic science laboratories to discover innovative ways to stimulate an individual patient&rsquo;s immune system to fight cancer and research how to enhance their tumor&rsquo;s immune microenvironment to make their cancer cells more susceptible to immunotherapy. I also have an interest in chemotherapeutic pharmacology and understanding how to precisely target each patient&rsquo;s tumor. Every patient&rsquo;s regimen is tailored by identifying and targeting the tumor&rsquo;s mutation and delivering a therapy based on a precision medicine approach.</p>
<p>I am passionate about giving every patient access to world-class heme malignancies care. The challenge is that some of our best therapies are only available at tertiary level cancer centers like Montefiore which is a long-distance travel for many patients. At the same time, patients benefit from getting their cancer care close to home, in their own community. As director of the Montefiore Hematologic-Malignancy Network, I have worked with our heme malignancy team to develop a Co&mdash;Management Model, where we collaborate with community medical oncologists to enable patients who live far from the Bronx access to novel therapies only available at an NCI designated Cancer Center.</p>

CHAM Provider
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Professional Title
M.D.
EMR ID
54204
Is Open Scheduling
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Swati Goel

Submitted by Anonymous (not verified) on
Full Name
Swati Goel
Profile Image URL
https://documentapi-fargate-documentbucket-15qi4tpdvnhlz.s3.amazonaws.com/218/a087ea30-62e8-11ed-870b-2b0ad85cb4ee.jpg
Type
Provider
Faculty
First Name
Swati
Last Name
Goel
NPI
1053632869
Faculty ID
13662
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-oncology
einstein-dept-medicine
Gender
Female
Phone
718-920-4137
Titles
Type
Academic
Department
Department of Oncology
Rank
Associate Professor
Division
Hematology
Type
Academic
Department
Department of Medicine
Department Link
Rank
Associate Professor
Division
Oncology & Hematology
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.87811 40.87956)
Address Line 1
3411 Wayne Avenue
City
Bronx
State
NY
Zip
10467-2509
Location Title
Montefiore At 3411 Wayne Avenue
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84475 40.84623)
Address Line 1
1695 Eastchester Road
City
Bronx
State
NY
Zip
10461
Location Title
Montefiore Medical Park at Eastchester
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84563 40.84596)
Address Line 1
1575 Blondell Avenue
City
Bronx
State
NY
Zip
10461-2601
Location Title
Montefiore Medical Park at 1575 Blondell
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8782381 40.8799784)
Address Line 1
Montefiore Medical Center
Address Line 3
3411 Wayne Avenue
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore Medical Center
Education and Trainings
Education Type Label
Medical Education
Education Institution
All-India Institute of Medical Sciences
Education Type Label
Fellowship
Education Institution
New York University School of Medicine
Education Type Label
Residency
Education Institution
Jacobi Medical Center
Professional Interests

<p>Dr. Swati&nbsp;Goel is an Assistant Professor of Medicine (Hematology). &nbsp;She completed medical school education&nbsp;at the All India Institute of Medical Sciences and finished postgraduate hematology-oncology&nbsp;training at NYU Langone Medical Center.</p>
<p>Dr. Goel sees patients with blood disorders and blood-related cancers.&nbsp;She&nbsp;specializes in the field&nbsp;of myeloproliferative disorders like myelofibrosis, polycythemia vera, and essential thrombocytosis. She is the leader of Myeloproliferative Disorder Clinic at Montefiore Einstein.</p>

Research Areas
Myelofibrosis, Myelodysplastic Syndrome, Polycythemia, Thrombocytosis
CHAM Provider
Off
Professional Title
M.B.,B.S.
Clinical Focus

Myeloproliferative neoplasms, and the conditions she treats include myelofibrosis, polycythemia vera, essential thrombocythemia, mastocytosis, eosinophilia, anemia and pancytopenia.

Research Focus

Myeloproliferative neoplasms

EMR ID
4908
Biography

<p>Swati Goel, MBBS, is Leader of the Myeloproliferative Disorder Clinic, Assistant Director of the Hematology-Oncology Fellowship Program and Associate Professor in the Department of Oncology and Medicine at Montefiore Einstein. Her area of clinical focus is myeloproliferative neoplasms, and the conditions she treats include myelofibrosis, polycythemia vera, essential thrombocythemia, mastocytosis, eosinophilia, anemia and pancytopenia.</p><p>After earning her Bachelor of Medicine, Bachelor of Surgery from the All-India Institute of Medical Sciences in New Delhi, India in 2006, Dr. Goel completed her residency in internal medicine at Montefiore Einstein in 2010. Afterward, she underwent a hematology-oncology fellowship at New York University School of Medicine, completing it in 2013.</p><p>Dr. Goel&rsquo;s research focus is myeloproliferative neoplasms. She is the principal investigator in many clinical trials involving myelofibrosis, polycythemia vera and essential thrombocythemia, and her work has been published in numerous peer-reviewed journals, articles and abstracts.</p><p>Dr. Goel is board certified in Internal Medicine, Medical Oncology and Hematology. She is a member of the American Society of Hematology and the American Society of Clinical Oncology. She is also the Clinical Competency Committee Leader and Program Evaluation Committee Member for the Hematology-Oncology Fellowship at Montefiore Einstein. In 2012, Dr. Goel won the Abstract Achievement Award for oral presentation at the American Society of Hematology Annual Meeting.</p>

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