Alyson K. Myers

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Alyson

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Myers

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1538326509

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17187

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168959

Biography

<p>Alyson K. Myers, MD, is Associate Professor, Endocrinology at our Albert Einstein College of Medicine. Dr. Myers is a clinical endocrinologist who cares for persons with diabetes, as well as disorders of the thyroid, bone, adrenals, pituitary and gonads.</p><p>After earning her Doctor of Medicine at the State University of New York Downstate Medical Center in 2005, Dr. Myers completed a combined internal medicine and psychiatry residency at Rush University Medical Center in 2010. In 2012, she completed a clinical endocrinology fellowship and a T32 diabetes and depression research fellowship at the University of Texas Southwestern Medical Center.</p><p>Building on her clinical focus, Dr. Myers&rsquo; research interests include diabetes disparities, diabetes technology and diabetic foot ulcers. She has been co-investigator and consultant on a number of funded research projects and has given numerous national and international presentations. Dr. Myers has shared her work through many peer-reviewed journals, books, chapters, review articles and abstracts.</p><p>Dr. Myers is board certified in Endocrinology, Diabetes, & Metabolism and Internal Medicine by the American Board of Internal Medicine. She is a member of many professional organizations, including the Association of Medicine and Psychiatry, the Endocrine Society and the American Association of Clinical Endocrinologists, among others.</p>

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Sofiya Milman

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Sofiya

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Milman

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1265726962

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12865

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<p>Dr. Sofiya Milman is Professor of Medicine and of Genetics, Interim Vice-Chair for Research in the Department of Medicine, and Director of Human Longevity Studies at Einstein’s Institute for Aging Research. Dr. Milman&rsquo;s research focuses on a unique population of centenarians and their families who are generally free of age-related diseases. Healthy longevity runs in most of these families, suggesting a heritable basis for this phenomenon.&nbsp;Dr. Milman's team conducts translational research focused on the discovery of genomic mechanisms that regulate endocrine and metabolic pathways that protect against common age-related diseases, like diabetes, cardiovascular disease and Alzheimer's.&nbsp;</p>
<p>Many of the discovered longevity genes and phenotypes are related to hormonal pathways. Changes in most hormones are observed throughout the human lifespan, but it remains unknown whether the observed changes cause aging, are associated with age but are not the cause of aging, or are protective for the aging body. Identification of protective endocrine parameters will inform our understanding of the mechanisms of healthy aging and lead to the discovery of interventions that protect from age-related diseases.</p>
<p>A biological pathway that has been repeatedly implicated in aging is the somatotropic axis that involves signaling via growth hormone and insulin-like growth factor-I (IGF-I). &nbsp;Substantial evidence exists that diminished signaling via this pathway delays aging, resulting in longer lifespan and health-span, not only in animal models, but also in humans. In fact, Dr. Milman's research demonstrated that&nbsp;lower IGF-I levels were associated with longer survival and better cognition in humans with exceptional longevity and provided evidence against supplementing older adults with growth hormone in an attempt to delay aging. Dr. Milman's team uses computational approaches to integrade genetic information, such as whole-exome sequencing, with rich phenotype data in families with inherited longevity to understand the genetic and molecular mechanisms that lead to protective effects of low IGF-I.&nbsp;</p>

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<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><!-- [if !supportLists]--><span style="font-size: 10.5pt; font-family: Verdana, sans-serif;">&nbsp; &nbsp; &nbsp;1. Zhang WB, Ye K, Barzilai N,&nbsp;<strong>Milman S</strong>. The antagonistic pleiotropy of insulin-like growth factor 1.&nbsp;<em>Aging Cell&nbsp;</em>2021;&nbsp;</span><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: #231f20; letter-spacing: -0.05pt; background-color: white;">20(9), e13443</span><span style="font-size: 10.5pt; font-family: Verdana, sans-serif;">;&nbsp;</span><span class="id-label"><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">PMCID: PMC8441393</span></span><span class="apple-converted-space"><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">&nbsp;</span></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><!-- [if !supportLists]--><span class="docsum-authors"><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: #212121;">&nbsp; &nbsp; &nbsp;</span></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><span class="docsum-authors"><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: #212121;">&nbsp; &nbsp; &nbsp;2. DeVito LM, Barzilai N, Cuervo AM, Niedernhofer LJ,&nbsp;<strong>Milman S</strong>, Levine M, Promislow D, Ferrucci L, Kuchel GA, Mannick J, Justice J, Gonzales MM, Kirkland JL, Cohen P, Campisi J. Extending human healthspan and longevity: a symposium report.&nbsp;<em>Ann NY Acad Sci&nbsp;</em>2021</span></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;">&nbsp;</p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">&nbsp; &nbsp; &nbsp;3. Zhang WB, Aleksic S, Gao T, Weiss EF, Demetriou E, Verghese J, Holtzer R, Barzilai N,<strong>&nbsp;Milman S.&nbsp;</strong><a href="https://pubmed.ncbi.nlm.nih.gov/32492897/?from_term=sofiya+milman&amp;f… style="color: black; text-decoration: none;">Insulin-like Growth Factor-1 and IGF Binding Proteins Predict All-Cause Mortality and Morbidity in Older Adults.</span></a>&nbsp;<em>Cells</em>&nbsp;2020; 9(6):E1368,&nbsp;PMCID:<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7349399/&quot; target="_blank" rel="noopener"><span style="color: black; text-decoration: none;">PMC7349399</span></a></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;">&nbsp;</p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><!-- [if !supportLists]--><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">&nbsp; &nbsp; &nbsp;4. Zhang ZD,&nbsp;<strong>Milman S</strong>, Lin J, Barzilai N, Gorbunova V, Ladiges WC, Niedernhofer LF, Suh Y, Robbins PD, Vijg J. Genetics of extreme human longevity to guide drug discovery for healthy ageing.&nbsp;<em>Nat Metab&nbsp;</em>2020; 2(8)663-672.</span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;">&nbsp;</p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><!-- [if !supportLists]--><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">&nbsp; &nbsp; &nbsp;5. Lehallier B, Gate D, Schaum N, Nanasi T, Lee SE, Yousef H, Moran Losada P, Berdnik D, Keller A, Verghese J, Sathyan S, Franceschi C,&nbsp;<strong>Milman S</strong>, Barzilai N, Wyss-Coray T. Undulating changes in human plasma proteome profiles across the lifespan.&nbsp;<em>Nat Med</em>&nbsp;2019; 25(12):1843-1850;&nbsp;PMCID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/pmc7062043/&quot; target="_blank" rel="noopener"><span style="color: black;">PMC7062043</span></a></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;">&nbsp;</p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><!-- [if !supportLists]--><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">&nbsp; &nbsp; &nbsp;6. Gubbi S, Quipildor GF, Barzilai N, Huffman DM,&nbsp;<strong>Milman S</strong>. 40 Years of IGF-1: IGF-1: the Jekyll and Hyde of the aging brain.&nbsp;<em>J Mol Endocrinol&nbsp;</em>2018; 61(1):T171-T185. PMCID: PMC5988994</span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;">&nbsp;</p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><!-- [if !supportLists]--><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">&nbsp; &nbsp; &nbsp;7. Gubbi S, Schwartz E, Crandall JP, Verghese J, Holtzer R, Atzmon G, Braunstein R, Barzilai N,&nbsp;<strong>Milman&nbsp;S</strong>. Effect of Exceptional Parental Longevity and Lifestyle Factors on Prevalence of Cardiovascular Disease in Offspring.&nbsp;<em>Am J Cardiol</em>&nbsp;2017</span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;">&nbsp;</p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><!-- [if !supportLists]--><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">&nbsp; &nbsp; &nbsp;8. Ismail K, Nussbaum L, Sebastiani P, Andersen S, Perls T, Barzilai N,&nbsp;<strong>Milman S</strong>. Compression of Morbidity is Observed Across Cohorts with Exceptional Longevity.&nbsp;<em>J Am Geriatr Soc</em>&nbsp;2016; 64(8):1583-91. PMCID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988893/"><span style="color: black;">PMC4988893</span></a></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;">&nbsp;</p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><!-- [if !supportLists]--><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">&nbsp; &nbsp; 9.</span><strong><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;"> Milman S</span></strong><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">, Huffman DM, Barzilai N. The Somatotropic Axis in Human Aging: Framework for the Current State of Knowledge and Future Research.&nbsp;<em>Cell Metab</em>&nbsp;2016; 23(6):980-9. PMCID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919980/"><span style="color: black;">PMC4919980</span></a></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;">&nbsp;</p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><!-- [if !supportLists]--><span style="font-size: 10.5pt; font-family: 'Verdana',sans-serif; mso-fareast-font-family: Verdana; mso-bidi-font-family: Verdana; color: black; mso-themecolor: text1;"><span style="mso-list: Ignore;">&nbsp; &nbsp; 10.<span style="font: 7.0pt 'Times New Roman';">&nbsp;</span></span></span><!--[endif]--><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">Perice L, Barzilai N, Verghese J, Weiss EF, Holtzer R, Cohen P,&nbsp;<strong>Milman S</strong>. Lower Circulating Insulin-like Growth Factor-I is Associated with Better Cognition in Females with Exceptional Longevity Without Compromise to Muscle Mass and Function.&nbsp;<em>Aging&nbsp;</em>Albany NY) 2016; 8(10): 2414-2424. PMCID:&nbsp;<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115897/"><span style="color: black;">PMC5115897</span></a></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;">&nbsp;</p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><span style="font-size: 10.5pt; font-family: 'Verdana',sans-serif; mso-fareast-font-family: Verdana; mso-bidi-font-family: Verdana; color: black; mso-themecolor: text1;"><span style="mso-list: Ignore;">&nbsp; &nbsp; 11.<span style="font: 7.0pt 'Times New Roman';">&nbsp;</span></span></span><!--[endif]--><strong><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">Milman S</span></strong><span style="font-size: 10.5pt; font-family: Verdana, sans-serif; color: black;">, Barzilai N. Dissecting the Mechanisms Underlying Unusually Successful Human Health Span and Life Span.&nbsp;<em>Cold Spring Harb Perspect Med</em>&nbsp;2015 Dec 4. PMCID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691799/"><span style="color: black;">PMC4691799</span></a>&nbsp;</span></p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;">&nbsp;</p>
<p class="MsoNormal" style="margin: 0in 0in 0in 0.5in; font-size: medium; font-family: Calibri, sans-serif; caret-color: #000000; color: #000000; font-style: normal; font-variant-caps: normal; font-weight: normal; letter-spacing: normal; orphans: auto; text-align: start; text-transform: none; white-space: normal; widows: auto; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; text-decoration: none; text-indent: -0.25in; background-color: white;"><span style="font-size: 10.5pt; font-family: Verdana, sans-serif;">&nbsp; &nbsp; &nbsp;12.<span style="font-stretch: normal; font-size: 7pt; line-height: normal; font-family: 'Times New Roman';">&nbsp;</span></span><!--[endif]--><strong><span style="font-size: 10.5pt; font-family: Verdana, sans-serif;">Milman S</span></strong><span style="font-size: 10.5pt; font-family: Verdana, sans-serif;">, Atzmon G, Huffman DM, Wan J, Crandall JP, Cohen P, Barzilai N. Low Insulin-like Growth Factor-1 Level Predicts Survival in Humans with Exceptional Longevity.&nbsp;<em>Aging Cell</em>&nbsp;2014; 13(4):769-71</span></p>

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Justin D. Mathew

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Justin

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Mathew

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Pedro P. Maria

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<span style="font-size:16px;-webkit-text-size-adjust:auto;caret-color:#525458;color:#525458;font-family:Arial, Helvetica, sans-serif;background-color:#ffffff;">Dr. Maria's clinical focus includes the treatment of patients with all forms of urologic disease.</span>

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<p><span style="color:#525458;font-family:Arial, Helvetica, sans-serif;background-color:#ffffff;">Pedro Maria, DO, obtained his medical degree from the Philadelphia College of Osteopathic Medicine. He completed his residency training in urology at the Albert Einstein Medical Center in Philadelphia, and he obtained fellowship training in minimally invasive and robotic surgery at Montefiore and Einstein. Dr. Maria's practice includes the treatment of patients with all forms of urologic disease. Dr. Maria has a particular interest in the treatment of male sexual dysfunction.</span></p>

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Anjali Manavalan

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Anjali

Last Name

Manavalan

NPI

1740502897

Faculty ID

15682

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Full Time

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Adult

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Female

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Primary Care

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Elsevier Profile

EMR ID

5581

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2499

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Franklin C. Lowe

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First Name

Franklin

Last Name

Lowe

NPI

1801971270

Faculty ID

14708

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Full Time

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Male

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Clinical Focus

Treatment of benign and malignant disorders of the prostate.<quillbot-extension-portal></quillbot-extension-portal>

Research Focus

Urological topics<quillbot-extension-portal></quillbot-extension-portal>

Elsevier Profile

EMR ID

73230

Biography

<p>Franklin C. Lowe, MD, Professor of Urology and Vice-Chair of the Department, is also Director of Urologic Services, Jack D. Weiler Hospital. An expert in the treatment of benign and malignant disorders of the prostate, Dr. Lowe has published over 150 articles on multiple urological topics and has lectured extensively throughout the world. Prior to joining The Department of Urology at Montefiore, Dr. Lowe held faculty and leadership positions at Columbia University, Mount Sinai School of Medicine and at St. Luke&rsquo;s/ Roosevelt Hospital in Manhattan. A Graduate of Princeton University, Dr. Lowe obtained both his Medical and Masters of Public Health degrees from Columbia University College of Physicians and Surgeons. He completed his internship and residency in Surgery and Urology at The James Buchanan Brady Urological Institute of Johns Hopkins University. Dr. Lowe previously served as the Chairman of The American Urological Association&rsquo;s Alternative Medicine Committee and as a member of the BPH Guidelines Committee.</p>

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Hanna Lee

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First Name

Hanna

Last Name

Lee

NPI

1609156512

Faculty ID

16456

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Full Time

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Adult

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Female

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EMR ID

114657

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2499

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Preeti Kishore

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First Name

Preeti

Last Name

Kishore

NPI

1477634806

Faculty ID

9299

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Adult

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Female

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<p style="font-family: 'Times New Roman'; font-size: 12.0pt; margin: 0pt 0pt .0001pt 0pt;"><span style="font-size: 10.0pt; font-family: Arial;">Dr. Preeti Kishore is a Professor in the Division of Endocrinology.&nbsp;</span><span style="font-family: Arial; font-size: 13.3333px;"> She is the site director for the Einstein/Montefiore Endocrinology Fellowship Program at Jacobi Medical Center. As Chief of the Endocrinology Division at Jacobi she is responsible for the clinical endocrine inpatient and outpatient operations at Jacobi and North Central Bronx Hospitals.</span><span style="font-family: Arial; font-size: 13.3333px;"> She actively participates in the teaching of endocrinology fellows, internal medicine residents and Einstein medical students. Her education philosophy is to empower learners to drive their own educational goals/learning. She is interested in the use of diabetes technology to manage low health literacy patients with diabetes. She is also the Director of the Weight Management Program at Jacobi.</span></p>
<p style="font-family: 'Times New Roman'; font-size: 12.0pt; margin: 0pt 0pt .0001pt 0pt;"><span style="font-family: Arial; font-size: 10pt;">Her research interests have been in Type 2 Diabetes Mellitus and the Insulin resistance syndrome. She has investigated the pathogenic role of free fatty acids in various aspects of </span><span style="font-family: Arial; font-size: 13.3333px;">Type 2 Diabetes Mellitus</span><span style="font-family: Arial; font-size: 10pt;">, particularly the role they play in regulating &ldquo;glucose effectiveness&rdquo;. She is also interested in the role of adipose tissue inflammation in the pathogenesis of the metabolic syndrome and insulin resistance. As an extension to her interest in adipose inflammation, she has investigated the role of vitamin D deficiency in Type 2 diabetes and whether it may regulate adipose inflammation/fibrosis. </span></p>
<p style="font-family: 'Times New Roman'; font-size: 12.0pt; margin: 0pt 0pt .0001pt 0pt;"><span style="font-family: Arial; font-size: 10pt;">Dr. Kishore is </span><span style="font-family: Arial; font-size: 13.3333px;">a member of the Leo M Davidoff Society and a</span><span style="font-family: Arial; font-size: 10pt;"> recipient of the prestigious Henry Christian Award of the American Federation of Medical Research. She is also the recipient of several teaching/advising awards.&nbsp;</span></p>

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Selected Publications

<p>Esterson YB, Carey M, Boucai L, Goyal A, Raghavan P, Zhang K, Mehta D, Feng D, Wu L, Kehlenbrink S, Koppaka S, Kishore P, Hawkins M.Central Regulation of Glucose Production May Be Impaired in Type 2 Diabetes. Diabetes. 2016 Sep;65(9):2569-79</p>
<p>Kishore P, Boucai L, Zhang K, Li W, Koppaka S, Kehlenbrink S, Schiwek A, Esterson YB, Mehta D, Bursheh S, Su Y, Gutierrez-Juarez R, Muzumdar R, Schwartz GJ, Hawkins M. Activation of K(ATP) channels suppresses glucose production in humans. J Clin Invest. 2011 Dec;121(12):4916-20</p>
<p>Kishore P, Li W, Tonelli J, Lee DE, Koppaka S, Zhang K, Lin Y, Kehlenbrink S, Scherer PE, Hawkins M. Adipocyte-derived factors potentiate nutrient-induced production of plasminogen activator inhibitor-1 by macrophages. Sci Transl Med. 2010 Feb 24;2(20):20ra15.</p>

EMR ID

4182

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Meredith A. Hawkins

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First Name

Meredith

Last Name

Hawkins

NPI

1922189356

Faculty ID

1982

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Female

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<p>Dr. Meredith Hawkins is Professor of Medicine and Associate Director of the Einstein-Mt. Sinai Regional Diabetes Research Center. She holds the Harold and Muriel Block Chair in Medicine. Dr. Hawkins earned her M.D. degree <em>cum laude</em> from the University of Toronto and a Master of Science in Clinical Research Methods <em>cum laude</em> from the Albert Einstein College of Medicine. She has served as Associate Editor of the <em>American Journal of Physiology</em>, and as Secretary Treasurer of the American Federation of Medical Research. Dr. Hawkins' current research interests include the effects of nutrient deficiency and excess on the pathogenesis of diabetes mellitus, central regulation of glucose metabolism, nutritional regulation of adipose tissue inflammation, and hypoglycemia-associated autonomic failure.</p>
<p>Dr. Hawkins is a Beeson Scholar of the American Federation of Aging Research, and has received research grants from the National Institutes of Health (continually since 1999), the American Diabetes Association, the Juvenile Diabetes Foundation International and the Diabetes Action Foundation International. She is the recipient of numerous honors and awards, including the Junior Physician Scientist Award (2001) and the Outstanding Investigator Award (2012) from the American Federation of Medical Research, the Novartis Young Investigator award in Diabetes Research (2007), and election to the American Society for Clinical Investigation (2012). She recently served on the Congressionally-appointed National Clinical Care Commission.&nbsp;</p>
<p>Dr. Hawkins founded and directs Einstein's Global Diabetes Institute (<a href="/centers/global-health/global-diabetes-institute/">http://www.einstein.yu.edu/centers/global-health/global-diabetes-instit…;, with the goal of building strategic partnerships in medical research and education to combat the burgeoning global diabetes epidemic.</p>

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<p class="MsoNormal" style="line-height: 15.6pt;"><span style="font-size: 9.0pt;">Dr. Hawkins specializes in diabetes, with a particular emphasis on the dramatic rise of the disease worldwide. She has traveled the globe investigating diabetes since 1996 and is the founding director of the Global Diabetes Institute (GDI) at Einstein, which conducts diabetes education and training for healthcare workers in South and Central America, Eastern Europe, Africa and Asia.</span></p>
<p class="MsoNormal" style="line-height: 15.6pt;"><span style="font-size: 9.0pt;">Dr. Hawkins also studies the role of nutrients and inflammation in the development of prediabetes and diabetes and is currently investigating the impact of vitamin D on the development and management of the disease.</span></p>
<p class="MsoNormal" style="line-height: 15.6pt;"><span style="font-size: 9.0pt;">In collaboration with researchers in India, Dr. Hawkins is investigating malnutrition diabetes, a little understood form of the disease that particularly affects the developing world.&nbsp;Dr. Hawkins is one of the organizers of an annual international conference for continuing medical education that alternates between Asia and Africa.&nbsp;Under Dr. Hawkins&rsquo; leadership, the GDI has partnered with faculty at Uganda&rsquo;s leading medical school to improve diabetes care in hospitals and clinics throughout the country. An NIH-funded researcher, Dr. Hawkins has received the Novartis Young Investigator in Diabetes and the Junior Physician Scientist Award of the American Federation of Medical Research.</span></p>

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Selected Publications

<p>Past 3 years:</p>
<ol>
<li><p>Wadivkar P, Thomas N, Jebasingh F, Bacot-Davis VR, Maini R, and Hawkins M. Undernutrition-Associated Diabetes Mellitus: Pathophysiology of a Global Problem. Physiology. 19 June 2025. doi: 10.1152/physiol.00065.2024.</p>
</li>
<li><p>Wadivkar P , Hawkins M. Is gestational diabetes mellitus in lean women a distinct entity warranting a modified management approach? Front. Clin. Diabetes Healthc., 06 May 2024.Sec. Diabetes and Pregnancy. doi: 10.3389/fcdhc.2024.1338597.</p></li>
<li>
<p>Carey M, Lontchi-Yimagou E, Mitchell W, Reda S, Zhang K, Kehlenbrink S, Koppaka S, Maginley SR, Aleksic S, Bhansali S, Huffman DM, Hawkins M. Central KATP channels modulate glucose effectiveness in humans and rodents. Diabetes. 2020 Jun;69(6):1140-1148. doi: 10.2337/db19-1256. PMID: 32217610 (Selected as Editor&rsquo;s Choice by Science Translational Medicine, 29 Apr 2020: Vol. 12, Issue 541, eabb5677).</p>
</li>
<li>
<p>Lontchi-Yimagou E, Aleksic S, Hulkower R, Gospin R, Goyal A, Kuo B, Mitchell WG, You JY, Upadhyay L, Carey M, Sandu OA, Gabriely I, Shamoon H, Hawkins M. Plasma epinephrine contributes to the development of experimental hypoglycemic-associated autonomic failure. Journal of Clinical Endocrinology and Metabolism 2020 Nov 1;105(11):dgaa539. doi: 10.1210/clinem/dgaa539.PMID: 32915987</p>
</li>
<li>
<p>Lontchi-Yimagou E, Kang S, Goyal A, You J-Y, Carey M, Rosen E, Kishore P, Hawkins M. Insulin Sensitizing Effects of Vitamin D Mediated through Reduced Adipose Tissue Inflammation and Fibrosis in Humans and Mice. Molecular Metabolism 2020 Dec;42:101095. doi: 10.1016/j.molmet.2020.101095. Epub 2020 Oct 10. PMID: 33045433&nbsp;</p>
</li>
<li>
<p>Brightwell CR, Kulkarni AS, Paredes W, Zhang K, Perkins JB, Gatlin KJ, Custodio M, Farooq H, Zaidi B, Pai R, Buttar RS, Tang Y, Melamed ML, Hostetter TH, Pessin JE, Hawkins M, Fry CS, Abramowitz MK. Muscle fibrosis and maladaptation occur progressively in CKD and are rescued by dialysis. JCI Insight. 2021 Dec 22;6(24):e150112. doi: 10.1172/jci.insight.150112. PMID: 34784301</p>
</li>
<li>
<p>Cefalu WT, Andersen DK, Arreaza-Rub&iacute;n G, Pin CL, Sato S, Verchere CB, Woo M, Rosenblum ND; Symposium planning committee, moderators, and speakers. Heterogeneity of Diabetes: &beta;-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases. Diabetes Care. 2022 Jan 1;45(1):3-22. doi: 10.2337/dci21-0051. PMID: 34782355</p>
</li>
<li>
<p>Lontchi-Yimagou E, DasGupta R, Kehlenbrink S, Koppaka S, Carey M, Stein DT, Thomas N, Hawkins M. An Atypical form of diabetes in low BMI individuals. Diabetes Care 2022 45(6):1428-1437. doi: 10.2337/dc21-1957. PMID: 35522035 (In the top 5% of all research outputs scored by Altmetric: as of July 13, 2023, the paper has received 8,874 reads and has been picked up by 94 news outlets.)</p>
</li>
<li>
<p>Lontchi-Yimagou E, Anoop S, Kurian ME, Ye K, Kehlenbrink S, Thomas N, Hawkins M. Response to Comment on Lontchi-Yimagou et al. An Atypical Form of Diabetes Among Individuals With Low BMI. Diabetes Care 2022;45:1428-1437. Diabetes Care. 2022 Nov 1;45(11):e159-e160. doi: 10.2337/dci22-0031.PMID: 36318676</p>
</li>
<li>
<p>Herman WH, Schillinger D, Bolen S, Boltri JM, Bullock A, Chong W, Conlin PR, Cook JW, Dokun A, Fukagawa N, Gonzalvo J, Greenlee MC, Hawkins M, Idzik S, Leake E, Linder B, Lopata AM, Schumacher P, Shell D, Strogatz D, Towne J, Tracer H, Wu S. The National Clinical Care Commission Report to Congress: Recommendations to Better Leverage Federal Policies and Programs to Prevent and Control Diabetes. Diabetes Care. 2023 Feb 1;46(2):255-261. doi: 10.2337/dc22-1587. PMID: 36701592</p>
</li>
<li>
<p>Greenlee MC, Bolen S, Chong W, Dokun A, Gonzalvo J, Hawkins M, Herman WH, Leake E, Linder B, Conlin PR. The National Clinical Care Commission Report to Congress: Leveraging Federal Policies and Programs to Improve Diabetes Treatment and Reduce Complications. Diabetes Care. 2023 Feb 1;46(2):e51-e59. doi: 10.2337/dc22-0621. PMID: 36701593</p>
</li>
<li>
<p>Cook J, Hawkins M, Pajvani UB. Liver insulinization as a driver of triglyceride dysmetabolism. Nature Medicine. 2023 (e-publication 17 July 2023)</p>
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</ol>

EMR ID

4098

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Eric J. Epstein

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First Name

Eric

Last Name

Epstein

NPI

1558427930

Faculty ID

10762

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<p>Dr. Epstein is an endocrinologist and professor of medicine in the division of endocrinology, who also currently serves as the vice chair of clinical affairs for the department of medicine (DOM).</p>
<p>Since joining the Montefiore Einstein faculty in 2007, Dr. Epstein has proven himself as an innovative, effective, and exceptional department leader. During his tenure as the medical director for the department of medicine faculty practice, from 2011- 2020, and then as vice chair for clinical affairs, he oversaw a year-over-year increase in wRVUs, improvement in the positive contribution margin, and continued growth in the department. Since his promotion to vice chair in 2020, Dr. Epstein has led all aspects of the department&rsquo;s clinical operations.</p>
<p>Dr. Epstein oversees the development of high-quality and cost-effective care while integrating new systems, processes, workflows, and procedures within the DOM faculty practice. While serving as the leader for the DOM clinical advisory council, he also acts as a liaison for DOM leadership and system partners, working with the faculty practice group, care management organization, and digital transformation office to foster program development and improve patient care and access to specialty medicine. Additionally, he has helped forge new programs within the DOM faculty practice, including the comprehensive weight management center and the new Einstein student health practice.</p>
<p>Dr. Epstein is also the course director for the endocrine systems course for Einstein medical students, for which he was inducted into the Leo M. Davidoff society and has garnered two teaching awards: the 2020 Harry Eagle Award and the Samuel M. Rosen outstanding Teacher Award in 2013. Dr. Epstein received his B.S degree from Cornell University and M.D. degree from the University of Chicago Pritzker School of Medicine. Following an internal medicine residency at New York Hospital/Cornell and Memorial Sloan Kettering, he completed fellowship training at the Montefiore Einstein endocrinology, diabetes, and metabolism fellowship training program.</p>

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4699

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