Mary K. Parras

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Mary

Last Name

Parras

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1588744064

Faculty ID

4937

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Adult

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Female

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EMR ID

3424

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Maja H. Oktay

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First Name

Maja

Last Name

Oktay

NPI

1912087404

Faculty ID

9053

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Full Time

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Adult

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Female

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<p>Maja Oktay, MD/Ph.D., is a physician-scientist. She is a board-certified anatomical pathologist and cytopathologist with a Ph.D. and post-doctoral training in cancer cell biology and cell signaling pathways. Her major interests are in cancer cell biology, the biology of breast cancer progression and metastasis, the effect of chemotherapy and endocrine therapy on the tumor microenvironment, racial disparity in cancer, as well as development of prognostic and predictive molecular biomarkers. Her work is based on the analysis of the cancer microenvironment using mouse models of cancer, intravital multiphoton imaging, and digital pathology as well as minimally invasive procedures for diagnosis and prognosis of human malignancies, such as fine-needle aspiration (FNA) biopsy.</p>
<p>Dr. Oktay is a translational (bench to bedside) researcher in Einstein&rsquo;s <a href="/research/integrated-imaging-program/">Integrated Imaging Program</a> where basic science findings are applied to clinical care through the integration and validation of high-resolution optical imaging with currently used clinical imaging methods.</p>
<p>Dr. Oktay established New York Pathology Oncology Group (NYPOG) and is the current director of NYPOG (https://einsteinmed.org/research/groups/ny-pathology-oncology/).</p>
<h3>Contribution to Science:</h3>
<p>Maja Oktay studies breast cancer microenvironments responsible for metastasis. In particular, the function of breast cancer intravasation sites called TMEM (Tumor MicroEnvironment of Metastasis) and its interactions with pro-metastatic Mena-expressing tumor cells and cancer stem cells. Using fine needle aspiration (FNA) biopsy obtained breast cancer cells from patients she determined that invasive cancer cells (MenaINV expressing) and cancer cells expressing stem cell markers correlate with TMEM score breast cancers from patients indicating mechanistic involvement of MenaINV, and stemness in TMEM function in human breast cancer. In addition, using FNA obtained cancer cells from patients for functional in vitro trans-endothelial migration studies she demonstrated that TMEM sites and MenaINV expression in cancer cells are essential for cancer cell trans-endothelial migration in all clinical subtypes of breast cancer. She also participated in the prospective validation study which demonstrated that TMEM score is a predictive marker of metastasis in breast cancer patients, as well as in the study which demonstrated that TMEM sites are functional sites of transient blood vessel permeability and as such the only sites of breast cancer cell intravasation. In addition, she led a study that established that commonly used chemotherapy for breast cancer can induce TMEM and MenaINV mediated pro-metastatic changes in breast cancer in the neoadjuvant setting and demonstrated that these changes can be reversed by Tie2 inhibition. More recently, Dr. Oktay co-led a study that elucidated the mechanism of induction of stem and invasive breast cancer cells. Using high-resolution intravital microscopy and a biosensor for cancer stem cells (CSC) the team also observed that CSCs display disseminating phenotype and using mouse and patient-derived breast cancers determined that tumor microenvironments, in particular around TMEM doorways, are sites of CSC induction.</p>
<p><strong>Mentoring:</strong></p>
<p><span style="font-size: 11.0pt; mso-bidi-font-size: 12.0pt; font-family: 'Arial',sans-serif; mso-fareast-font-family: 'Times New Roman'; mso-bidi-font-family: 'Times New Roman'; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">Throughout her career, Dr. Oktay served as a mentor to junior colleagues. She trained numerous individuals at various stages of their careers including high school students, MD/Ph.D. students, pathology residents, and cytopathology fellows, as well as post-doctoral fellows and junior faculty.&nbsp; During the past 10 years, she trained 5 pre- and 15 post-doctorates, all of whom have continued in research or research-related careers. Moreover, she has been mentoring T32 fellows since 2015, with 7 trainees in total. Most of the training interactions have resulted in publications or grant submissions and funded grants.&nbsp;</span></p>
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<p><a class="button expand-for-small-only" title="View Maja Oktay's bibliography" href="https://www.ncbi.nlm.nih.gov/myncbi/maja.oktay.1/bibliography/public/">… Bibliography</a></p>
<p style="font-variant-ligatures: normal; font-variant-caps: normal; orphans: 2; text-align: start; widows: 2; -webkit-text-stroke-width: 0px; text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; word-spacing: 0px;"><a href="https://www.ncbi.nlm.nih.gov/myncbi/maja.oktay.1/bibliography/public/">…;
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EMR ID

4398

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Clelia E. Moline

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First Name

Clelia

Last Name

Moline

NPI

1740371392

Faculty ID

16018

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Full Time

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Adult

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Female

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Elsevier Profile

EMR ID

4453

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Rishabh Mishra

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First Name

Rishabh

Last Name

Mishra

NPI

1912312570

Faculty ID

17451

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Full Time

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Adult

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Male

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Elsevier Profile

EMR ID

13911

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Mark D. Levie

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First Name

Mark

Last Name

Levie

NPI

1891875365

Faculty ID

5805

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Full Time

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Adult

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Male

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Elsevier Profile

EMR ID

3785

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Rubina S. Khokhar

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First Name

Rubina

Last Name

Khokhar

NPI

1487751137

Faculty ID

12291

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Full Time

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Adult

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Female

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Dr. Khokhar's&nbsp;clinical focus centers on teaching obstetrics &amp; gynecology to medical students and residents.

Elsevier Profile

EMR ID

5032

Biography

<p>Rubina Shakil Khokhar, MD, is an attending physician and Assistant Professor, Obstetrics &amp; Gynecology at Montefiore Einstein. She is also Clerkship Site Leader, Wakefield Campus for Medical Education-Ob/Gyn. Her clinical focus centers on teaching obstetrics &amp; gynecology to medical students and residents.</p><p>After obtaining her Bachelor of Medicine and Bachelor of Surgery in 1987 from Nishtar Medical College in Multan, Pakistan, Dr. Khokhar completed her residency in obstetrics &amp; gynecology at Nishtar Hospital in 1987. She then completed another residency in obstetrics &amp; gynecology at Azad Jammu and Kashmir Hospital in Muzaffarabad, Pakistan, in 1991. Following this, Dr. Khokhar participated in an obstetrics &amp; gynecology fellowship at Post-Graduate Institute in Lahore, Pakistan, completing it in 1992. Dr. Khokhar then came to New York Hospital Medical Center of Queens (Cornell University) to complete a residency in general surgery in 1999 before completing an additional residency in obstetrics &amp; gynecology at Our Lady of Mercy Medical Center, University Hospital of New York Medical College in 2006.</p><p>Dr. Khokhar is board certified by the American Board of Obstetrics and Gynecology and is a member of the American College of Obstetric &amp; Gynecology (ACOG). She speaks English, Hindi, Urdu, Punjabi and Medical Spanish. She has received accolades for excellence in teaching medical students, including recognition by the Leo M. Davidoff Society and receiving a certificate of appreciation for excellence in teaching from NY Medical College, 2003 &ndash; 2006.</p>

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Rouzan G. Karabakhtsian

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First Name

Rouzan

Last Name

Karabakhtsian

NPI

1881624963

Faculty ID

14851

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Full Time

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Adult

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Female

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Elsevier Profile

EMR ID

4629

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Ester Ilyayeva

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First Name

Ester

Last Name

Ilyayeva

NPI

1508210493

Faculty ID

19428

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Full Time

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Adult

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Female

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Primary Care

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EMR ID

113945

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Neal D. Hoffman

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First Name

Neal

Last Name

Hoffman

NPI

1336225606

Faculty ID

4641

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Full Time

Patient Type

Pediatric

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Male

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On

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Clinical Focus

<p>Adolescent reproductive health care, including long-acting reversible contraception, adolescent sexual health, adolescent gynecology, eating disorders, young men&rsquo;s health</p>

Research Focus

<p>Adolescent health risk screening and prevention, contraceptive choices, shared decision-making, adolescent perspectives on health care access.</p>

Elsevier Profile

EMR ID

3849

Biography

<p>Neal D. Hoffman, MD, is an Attending Physician in the Division of Academic General Pediatrics at Montefiore (CHAM), and an Associate Professor of Pediatrics at the Albert Einstein College of Medicine. His clinical focus is in general pediatrics and adolescent medicine, with interests in school-based health care, chronic illness management and reproductive and sexual health. Dr. Hoffman joined Montefiore's School Health Program in 2002, where he was Medical Director from 2005-2017. Dr. Hoffman was the Medical Director at Montefiore's Adolescent AIDS Program from 1994 to 2001. </p><p>Dr. Hoffman attended Boston University, where he received his Bachelor of Arts and Doctor of Medicine in 1987. He completed a Medical Internship at St. Luke's-Roosevelt Hospital Center in 1988. From 1988 to 1991, he was Pediatric Resident at Montefiore Medical Center/Albert Einstein College of Medicine, after which he was Pediatric Chief Resident for one year. From 1992-1994, Dr. Hoffman completed a fellowship in Adolescent Medicine at Montefiore Medical Center/Albert Einstein College of Medicine. </p><p>Dr. Hoffman is currently the Principal Investigator of a 5-year NIDA-funded R01 Implementation Science Project on universal HIV testing and targeted HIV prevention protocol in school-based health centers. He completed a fellowship in 2016-2017 in Practice-Based Research Methodology through an AHRQ-funded program at Case Western University Medical Center, when he started developing a research study to compare adolescent and parent responses for assessment of asthma severity and control. Dr. Hoffman participated in the Performance Improvement Course at the Children's Hospital at Montefiore in 2018. Dr. Hoffman's research has been published in numerous reviewed journals and articles, book chapters, and abstracts. </p><p>In 2013, Dr. Hoffman received the Bronx Community Health Network Community Health Leadership Award. He is board certified by the American Board of Pediatrics and Adolescent Medicine. He is also a member of the American Academy of Pediatrics and the Society for Adolescent Health and Medicine. </p>

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Angela E. Gonzalez

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First Name

Angela

Last Name

Gonzalez

NPI

1700817475

Faculty ID

16017

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Adult

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Female

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Elsevier Profile

EMR ID

4435

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