Ehren I. Ekhause
David M. Loeb
<p>Dr. Loeb has an active translational research laboratory focused on understanding bone tumor metastasis. His laboratory developed a clinically relevant mouse model of sarcoma metastasis, and has used this model to perform preclinical testing of novel agents that can interfere with this process. More basic scientific studies in the lab involve exploring the role of the Wnt signaling pathway in Ewing sarcoma migration, invasion, and metastasis. Dr. Loeb is also studying the role of an enzyme called RNA helicase DDX3 in Ewing sarcoma biology, especially how this enzyme affects the repair of damaged DNA. More recently, the laboratory has developed an interest in targeting the metabolic reprogramming associated with metastasis as a way to prevent the outgrowth of distant metastases from disseminated tumor cells.</p>
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<p>Dr. Loeb is also actively involved in clinical research, including the development of radiopharmaceutical agents for the treatment of bone metastases and the development of a small molecule inhibitor of DDX3. He serves as the local PI for a clinical trial of reduced intensity haploidentical bone marrow transplantation for children with high risk solid tumors. Finally, as an offshoot of his laboratory work, Dr. Loeb is involved in the development of biomarkers of metastatic risk and of minimal residual disease in children, adolescents, and young adults with sarcomas.</p>
<p>Dr. Loeb is a leading pediatric oncologist and NIH-funded researcher. He has extensive expertise in sarcoma research and clinical care and is a bone marrow transplantation specialist. Dr. Loeb’s research spans the spectrum from basic and translational studies to clinical trials using novel therapies.</p>
<p>Dr. Loeb's PubMed bibliography can be found here: </p>
<p><a href="https://www.ncbi.nlm.nih.gov/sites/myncbi/1fiIspwqfwUE46/bibliography/5…;
<p>David Loeb, MD, PhD, is Chief, Pediatric Hematology, Oncology and Cellular Therapy at Children’s Hospital at Montefiore and Professor, Pediatrics and Professor, Developmental and Molecular Biology at Montefiore Einstein. His clinical work focuses on tumors of connective tissue, such as bone and muscle. He also has expertise in the care of children with other solid tumors. As a member of the bone marrow transplantation team, Dr. Loeb also cares for patients with acute leukemias and has expertise in the application of immunotherapy to childhood cancer.</p><p>Dr. Loeb earned his Bachelor of Arts in biology in 1987 at Johns Hopkins University. In 1993, he received his Doctor of Philosophy in Pathology and, in 1994, his Doctor of Medicine at Columbia University. In 1994, he also began an internship in Pediatrics at the Johns Hopkins University School of Medicine, followed by a residency in 1995 and a fellowship in Pediatric Hematology Oncology at the same institution.</p><p>Dr. Loeb has an active translational research laboratory focused on understanding bone tumor metastasis. His laboratory developed a clinically relevant mouse model of sarcoma metastasis and has used this model to perform preclinical testing of novel agents that can interfere with this process. One area of focus is the metabolic differences between cancer cells and normal cells, and between metastases and the primary tumor, with the intention of targeting these differences therapeutically. More basic scientific studies in the lab involve exploring the role of the Wnt signaling pathway in Ewing sarcoma and osteosarcoma migration, invasion and metastasis. Dr. Loeb also studies the role of an enzyme called RNA helicase DDX3 in Ewing sarcoma biology, especially how this enzyme affects the repair of damaged DNA.</p><p>Dr. Loeb is also actively involved in clinical research, including the development of radiopharmaceutical agents for the treatment of bone metastases and the development of a small molecule inhibitor of DDX3. He has also directed a clinical trial of reduced intensity haploidentical bone marrow transplantation for children with high risk solid tumors. Stemming from his laboratory work, Dr. Loeb is involved in the development of biomarkers of metastatic risk and of minimal residual disease in children, adolescents and young adults with sarcomas. Dr. Loeb’s original research, based on his clinical and laboratory studies, has been published in multiple journals and books.</p><p>Dr. Loeb has been a recipient of many awards, including the Director’s Teaching Award in Clinical Science from Sidney Kimmel Comprehensive Cancer Center in 2006, 2010 and 2015, and The Justin Straus Chordoma Research Award in 2009.</p>
Beth R. Zell
Amanda N. Zayde
<p>Dr. Amanda Zayde is a licensed clinical psychologist at the Child Outpatient Psychiatry Department at Montefiore Medical Center Wakefield Division where she specializes in the treatment of children, adolescents, and emerging adults. She is also the Director and PI of the Connecting and Reflecting Experience (CARE): a transdiagnostic, bi-generational, mentalizing-focused group parenting program. She is the principal investigator of the program’s ongoing community-based clinical trial supported by the FAR Fund, and co-investigator for a series of research grants funded by the Tufts Clinical and Translational Science Institute and the National Institute of Mental Health. Dr Zayde is also Associate Director of the Psychology Internship Training Program, and co-Director of the Becoming an Emerging Adult at Montefiore (BEAM) program. Dr. Zayde received her Psy.D. from the George Washington University and completed her internship and postdoctoral training at the Yale School of Medicine. </p>
Dr. Zayde's clinical interests are in mentalizing-focused parenting interventions, assessment and treatment of adolescents and emerging adults, and developmental psychopathology and attachment science.
Dr. Zayde is Principal Investigator of the CARE program’s ongoing community-based clinical trial supported by the FAR Fund, and co-investigator for a series of research grants funded by the Tufts Clinical and Translational Science Institute and the National Institute of Mental Health.
<p><a href="https://pubmed.ncbi.nlm.nih.gov/32072881/">The Connecting and Reflecting Experience (CARE): theoretical foundation and development of mentalizing-focused parenting groups - PubMed (nih.gov)</a></p>
<p><a href="https://www.tandfonline.com/doi/abs/10.1080/23794925.2018.1551092">http…;
<p><a href="https://pubmed.ncbi.nlm.nih.gov/34525847/">Connection During COVID-19: Pilot Study of a Telehealth Group Parenting Intervention - PubMed (nih.gov)</a></p>
<p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8280593/">Mothering from the Inside Out: Addressing the Intersection of Addiction, Adversity, and Attachment with Evidence-Based Parenting Intervention (nih.gov)</a></p>
<p><a href="https://pubmed.ncbi.nlm.nih.gov/36862314/">https://pubmed.ncbi.nlm.nih…;
<p><a href="https://www.frontiersin.org/articles/10.3389/fpsyg.2022.911069/full">ht…;
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<p>Amanda Zayde, PsyD, is Director of the Connecting and Reflecting Experience (CARE) Program and Associate Director of Psychology Internship Training – Combined Track at Montefiore. She is also Co-Developer, Becoming an Emerging Adult at Montefiore (BEAM) and Assistant Professor at our Albert Einstein College of Medicine. Her clinical interests are in mentalizing-focused parenting interventions, assessment and treatment of adolescents and emerging adults, and developmental psychopathology and attachment science.
</p><p>After receiving her Bachelor of Arts at the State University of New York at Albany in 2001, Dr. Zayde earned her Doctor of Psychology at the George Washington University in 2011. Her pre- and postdoctoral training took place at Yale University School of Medicine, first as a predoctoral psychology fellow from 2010 to 2011, then as a postdoctoral psychology associate from 2011 to 2012.
</p><p>Dr. Zayde is active in training and mentorship and has been recognized for her research. She is Principal Investigator of the CARE program’s ongoing community-based clinical trial supported by the FAR Fund, and co-investigator for a series of research grants funded by the Tufts Clinical and Translational Science Institute and the National Institute of Mental Health. She is a member of the American Psychological Association.
</p><p>Dr. Zayde’s work has been published in peer-reviewed journals and shown at national and international conferences. She also provides the news media with expert insights on relationships, stress management, parenting, emerging adulthood, and child psychology.
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Rebecca L. Winkel
<p>Unhoused populations, infant mental health, toddler mental health, developmental disabilities, foster care and child welfare, attachment, adoption, perinatal mood disorders, trauma, Child Parent Psychotherapy (CPP), Trauma-Focused Cognitive Behavioral Therapy (TF-CBT)</p>
Dawn M. Wahezi
<p>Dr. Wahezi attended medical school at the University of Buffalo, School of Medicine and Biomedical Sciences. She completed her residency training in Pediatrics at The Children’s Hospital at Montefiore, where she stayed on as the inaugural fellow in Pediatric Rheumatology. She subsequently joined the faculty in the Department of Pediatrics at Montefiore and completed a Master’s Degree in clinical research through the Einstein-Montefiore Institute for Clinical and Translational Research Program. Dr. Wahezi is currently an Assistant Professor of Pediatrics at the Albert Einstein College of Medicine and serves as the Program Director of the Pediatric Rheumatology Fellowship Program. </p>
<p>Dr. Wahezi has a special interest in juvenile dermatomyositis (JDM) and was awarded the Cure JM Foundation Early Investigator Award for her research in premature atherosclerosis. She has additionally established a pediatric Systemic Lupus Erythematosus (SLE) Cohort and participates in a dedicated, multi-disciplinary pediatric Lupus Nephritis Clinic. Dr. Wahezi is currently engaged in several research projects within the domains of JDM and SLE, contributing to over 40 peer reviewed manuscripts, reviews and scientific abstracts.</p>
<p>Dr. Wahezi is an active member of both the JDM subcommittee and SLE subcommittee within the Childhood Arthritis and Rheumatology Research Alliance (CARRA) and has participated in numerous observational and comparative effectiveness research protocols through this research consortium. </p>
<span style="color:#4d4d4d;font-family:Arial, Helvetica, source-code-pro, Menlo, Monaco, Consolas, 'Courier New', monospace;font-size:16px;background-color:#ffffff;">Pediatric Rheumatology</span>
Dr. Wahezi has a particular research interest in juvenile dermatomyositis (JDM) and was awarded the Cure JM Foundation Early Investigator Award for her research in premature atherosclerosis.
<p></p>Dawn Wahezi, MD, MS, is Chief of the Division of Pediatric Rheumatology and Director of the Pediatric Rheumatology Fellowship Program at the Children’s Hospital at Montefiore. She is also Associate Professor of Pediatrics at our Albert Einstein College of Medicine.<br /><br />Dr. Wahezi received her Bachelor of Science from Loyola College and earned her Doctor of Medicine at the State University of New York at Buffalo, Jacobs School of Medicine and Biomedical Sciences. She obtained a Master of Science in Clinical Research at Albert Einstein College of Medicine, and did her residency and fellowship training at CHAM.<br /><br />Dr. Wahezi’s clinical and research interests include juvenile dermatomyositis (JDM) and juvenile systemic lupus erythematosus (SLE). At CHAM, she established an interdisciplinary clinic and comprehensive patient registry for children with JDM and SLE.. Dr. Wahezi is an active member of the American Academy of Pediatrics Rheumatology Advisory Board and the Childhood Arthritis and Rheumatology Research Alliance (CARRA).<p></p>
Rubiahna L. Vaughn
Jamie T. Twaite
Dr. Twaite’s clinical focus is on the neuropsychological evaluation and rehabilitation of individuals with cognitive and emotional concerns related to neurologic, medical, and psychiatric illness. She has a particular interest in the diagnosis and management of dementias and acquired brain injury(ABI), as well as in the rehabilitation of of spinal cord injury (both with and without concurrent ABI).<quillbot-extension-portal></quillbot-extension-portal>
Dr. Twaite’s research interests include cognitive and emotional functioning following stroke, TBI, and other acquired brain injury, as well as in individuals with Parkinson’s disease and in healthy populations, such as musicians.<quillbot-extension-portal></quillbot-extension-portal>
<p>Jamie Twaite, PhD, is a Neuropsychologist, Co-Director, Burke Rehabilitation Hospital’s Concussion Management Program, Director, Neuropsychology Externship and Assistant Professor, Physical Medicine and Rehabilitation at Montefiore Einstein. Her clinical focus is on the neuropsychological evaluation and rehabilitation of individuals with cognitive and emotional concerns related to neurologic, medical and psychiatric illnesses. She has a particular interest in the diagnosis and management of dementia and acquired brain injury (ABI), as well as in the rehabilitation of spinal cord injury (both with and without concurrent ABI).</p><p>After completing her Master of Psychology at Columbia University in 2008, Dr. Twaite pursued her Doctor of Philosophy in psychology at City University of New York (CUNY), earning the degree in 2016. That same year, she completed an APA-accredited predoctoral internship in clinical psychology-adult neuropsychology track with the Henry Ford Health System. She then went on to complete her postdoctoral fellowship in clinical neuropsychology with the Institute of Living, Hartford Hospital, with focused training in the assessment of memory disorders/dementias, acquired brain injuries, and severe and persistent mental illness.</p><p>Dr. Twaite’s research interests include cognitive and emotional functioning following stroke, traumatic brain injury (TBI) and other acquired brain injury in individuals with Parkinson’s disease as well as in healthy populations, such as in musicians. Her work has been published in numerous peer-reviewed journals and she has given paper and poster presentations at scientific meetings nationally and internationally. Dr. Twaite is a reviewer for the <em>Journal of Clinical and Experimental Neuropsychology</em> and the <em>Journal of Psycholinguistic Research</em>.</p><p>Dr. Twaite is a member of several professional associations, including the American Psychological Association (APA), the Society for Clinical Neuropsychology and the International Neuropsychological Society. In 2013, Dr. Twaite received the Graduate Center Doctoral Student Research Grant from CUNY.</p>