Betsy Herold
<p><strong>Betsy Herold, M.D.</strong> directs a basic and translational research program, which focuses on virus host interactions. Projects in the lab include studies designed to identify the cellular signaling pathways that herpes simplex viruses (HSV) usurp to promote viral entry and infection. The lab uncovered a previously unappreciated paradigm associated with activation of phospholipid scramblases, which are known to catalyze the movement of phosphatidylserine lipids between the inner and outer leaflet of the plasma membrane. Surprisingly, they found that the exofacial movement of phospholipids is associated with concomitant translocation of intracellular proteins, including the master kinase Akt to the outside, where Akt becomes phosphorylated to activate an “outside-inside” signaling cascade that promotes viral entry. This pathway is also usurped by SARS-CoV-2 and is important for cellular processes including apoptosis. In collaboration with the Almo lab, they have engineered cell impermeable kinase inhibitors. These compounds block viral entry and prevent induction of apoptosis by select TNF ligands.</p>
<p> Serendipitously, in studying this signaling pathway, the lab identified a novel candidate vaccine for the prevention and treatment of HSV infections. Most efforts to develop a vaccine have focused on neutralizing antibodies that target HSV glycoprotein D (gD), but all of these have failed in clinical trials. Instead, the lab (in collaboration with the Jacobs lab), engineered a virus completely deleted in gD. Glycoprotein D is required for viral entry and cell-to-cell spread, thus the deletion virus (DgD-2) is restricted a single cycle and will not spread. This candidate vaccine elicits T cell responses and high titer, polyfunctional antibodies that protect through antibody-dependent cell mediated cytotoxicity (ADCC). The vaccine prevents the establishment of latency in mice and is significantly more protective in multiple small animal models than prior vaccines that have failed in clinical trials. The lab has subsequently isolated monoclonal antibodies (mAbs) that have this protective ADCC activity and both the vaccine and the mAbs are being advanced for preclinical development. Studies to understand why this vaccine elicits ADCC-mediating antibodies whereas gD vaccines and primary HSV infection only elicit neutralizing antibodies led to the identification of a key role for TNFRSF14 (aka HVEM) in generating and mediating ADCC responses. HVEM is an immune cell surface protein that functions in signal transduction pathways that regulate inflammatory or inhibitory immune responses but its role in shaping the B cell repertoire and in providing a second signal for ADCC had not been previously described and has implications for vaccine development and oncolytic therapies. </p>
<p> The third major area of basic research involves defining the molecular mechanisms underlying the HIV-HSV syndemic. Epidemiological studies have consistently demonstrated that being HSV seropositive is associated with an increased risk for HIV acquisition, replication, higher plasma viral loads and more frequent episodes of HIV reactivation. Using primary cells from patients and HIV latently infected cell lines, the lab has identified several mechanisms by which HSV promotes HIV latency reversal and replication including upregulation of the noncoding RNA, <em>Malat1</em>, and downregulation of IL-32. Defining these pathways may lead to identification of new strategies to “shock and kill” or “block and lock” HIV.</p>
<p> Clinical studies include prevention of infectious disease complications in transplantation. Members of the research group are involved in studies to optimize pre-emptive prophylaxis for CMV and EBV, vaccine responses in transplantation recipients, and others</p><p>Studies with vaginal microbicides have resulted in the expnasion of studies to focus on soluble mucosal immunity in the genital tract. We found that .female genital tract secretions collected from healthy women provide variable, but significant protection against both HSV and HIV. Mechanistic studies suggest that this endogenous activity is mediated by defensins and other antimicrobial peptides. This endogenous activity may serve as a biomarker of a "healthy mucosal immune environment" and thus provide a surrogate marker to evaluate the safety of vaginal microbicides. In addition, identification of the mediators that contribute to this endogenous activity could lead to development of new strategies to boost this host defense and help protect against infection. These studies are being conducted in collaboration with the proteomics core facility at AECOM. Additionally, we are testing the hypothesis that HSV triggers changes in the mucosal environment, which allow it to escape cervical secretion defenses, enhance its own infectivity and facilitate HIV co-infection. Our preliminary observations support the paradigm that HSV disrupts the epithelial barrier by targeting tight junction and adherens junction proteins, and interferes with host defenses by triggering an inflammatory response and a loss in protective proteins such as SLPI. These changes could facilitate both its own infectivity and enhance HIV co-infection.<br /><br /></p>
<p>Results obtained from this bench research are critical to the laboratory's translational studies. The focus of the Translational Microbicide Research Program is to identify optimal combinations of topical microbicides that are safe and target different steps in HIV life cycle, thus reducing the risks of drug resistance and providing greater protection than could be achieved with a single agent, and also target HSV infection. Candidate combinations are evaluated using a multi-tiered approach for anti-viral activity and safety using human cervical cultures, as well as primary T cells and macrophages, in the presence of cervicovaginal secretions and seminal plasma. Leading combinations are then evaluated in human explant cultures (cervical, vaginal) and in murine genital models and a new cotton rat model for anti-viral activity and for the impact on mucosal immunity. If results of these pre-clinical studies suggest that candidate microbicides are safe and effective, the drugs are advanced for regulatory testing, and undergo evaluation in Phase I clinical studies.<br /><br /></p>
<p>Clinical research interests also include prevention of infectious disease complications in transplantation. Members of the research group are involved in studies to optimize pre-emptive prophylaxis for CMV and EBV, vaccine responses in transplantation recipients, and other related infectious complications.<br /><br /></p>
<div>Dr. Herold directs a translational research program focused on the interactions between viruses and their host and using that knowledge to develop novel treatment and prevention strategies. Through her basic science studies, Dr. Herold has developed a unique candidate vaccine to prevent herpes simplex virus (HSV) infections, which is being advanced for phase I clinical trials. Studies of this vaccine uncovered a previously unappreciated immune evasion strategy; this knowledge may accelerate the development of drugs to bolster vaccine and monoclonal antibody efficacy against a range of pathogens. </div>
<div><span style="white-space: pre;"> </span> </div>
<div>Her studies on HIV focus on the development of safe and effective pre-exposure prophylactic strategies and on investigating how HSV interacts with HIV to reactivate HIV. Dr. Herold's team also has discovered a previously unrecognized phenomenon in cell biology in which HSV and other viruses activate a mechanism that helps them gain entry and infect healthy cells. This provides a novel target for the development of new antiviral drugs. <br /><br /></div>
<div>Most recently, her lab has studied why children respond differently and are relatively protected from severe COVID-19. Defining the differences in the immune response in children compared to adults will provide insights into protective immunity against this virus and future pandemic viruses. <br /><br /></div>
<div>Her clinical research focuses on infections in pediatric transplant recipients. Dr. Herold helped established and is co-chair of the Pediatric Infectious Diseases Society Transplant Research Network (PIDTRAN), which supports and promotes projects to prevent and treat infectious diseases among child transplant recipients. Dr. Herold has served on the Office of AIDS Research Advisory Council and on the Pediatric Infectious Diseases Society Council. She has been continuously funded by the NIH since 1989. Dr. Herold has over 180 publications in peer-reviewed journals and has presented her work internationally.</div>
Pediatric Infectious Diseases.
Prevention and treatment of infections in solid and stem cell transplant patients and other immunocompromised patients.
<p>Betsy Herold, MD, is Chief of the Division of Pediatric Infectious Diseases and Vice Chair for Research at Children's Hospital at Montefiore. Dr. Herold is also a Professor of Pediatrics, Microbiology & Immunology, and Obstetrics & Gynecology and Women's Health at our Albert Einstein College of Medicine. She specializes in pediatric infectious diseases. </p><p>Dr. Herold received her Bachelor of Arts in Biology in 1978 from Brown University and went on to receive her Doctor of Medicine from the University of Pennsylvania Medical School in 1982. Dr. Herold completed an internship and residency in pediatrics at Children's Memorial Hospital, where she became a Chief Resident in 1985. She then began a fellowship in research at Hagedorn Research Laboratory in Gentofte, Denmark. In 1987, Dr. Herold began a fellowship in pediatric infectious diseases at Children's Memorial Hospital, followed by a Research Associate/Postdoctoral Virology Fellowship in the Department of Microbiology and Immunology at Northwestern University in Chicago. </p><p>Dr. Herold's clinical research focuses on the prevention and treatment of infections in solid and stem cell transplant patients and other immunocompromised patients. Dr. Herold has also been involved in research in Kawasaki disease and the emergence of methicillin-resistant staphylococcus aureus (MRSA) in the community. Dr. Herold directs a basic and translational research program on the prevention of herpes simplex virus (HSV) and HIV infections through the development of vaccines and novel antivirals. The current major focus of her lab is on a novel, paradigm-shifting, single-cycle vaccine to prevent HSV-1 and HSV-2. She has been continuously funded by the NIH since 1989. Dr. Herold has over 150 peer reviewed publications in peer-reviewed journals and has presented her work internationally. </p><p>In 2012, Dr. Herold received the Clinical Science Faculty Mentor Award from the Albert Einstein College of Medicine. She has also been awarded the Henry and Jacob Lowenberg Prize in Pediatrics and the Pediatric Infectious Disease Young Investigator Award. Dr. Herold is board certified by the American Board of Pediatrics in Pediatrics and in Pediatric Infectious Diseases. </p>
Patricia A. Hametz
Dr. Hametz's clinical focus is on providing family-centered care for all hospitalized children and on developing and implementing systems of care for children with medical complexities.
Dr. Hametz’s research focuses on improving care and the systems in which care is provided to hospitalized children and adolescents, and their families.
<p>Patricia A. Hametz, MD, MPH, is Chief of the Division of Pediatric Hospital Medicine at Children’s Hospital at Montefiore Einstein (CHAM). As Chief, she oversees the care of children admitted to the general pediatrics service, consultation service and co-management of patients on the pediatric surgery and surgical subspecialty services. She is also an Attending Physician at CHAM and an Associate Professor of Pediatrics at Albert Einstein College of Medicine. Her clinical focus is on providing family-centered care for all hospitalized children and on developing and implementing systems of care for children with medical complexities.</p><p>Dr. Hametz received her Doctor of Medicine in 1995 from Columbia University College of Physicians and Surgeons in New York. In 2008, she received her Master of Public Health from Columbia University Mailman School of Public Health. Dr. Hametz completed an internship and residency in Pediatrics at Morgan Stanley Children's Hospital of New York from 1995 to 1999 and became Chief Resident in 1998.</p><p>Dr. Hametz’s research focuses on improving care and the systems in which care is provided to hospitalized children and adolescents, and their families. Her original communications have been published in numerous peer-reviewed journals, as well as invited publications. She has been an invited speaker to regional and local presentations.</p><p>Dr. Hametz has been recognized as an outstanding teacher, was nominated for the Attending Teacher of the Year Award several times and also won the Pediatric Residency Appreciation Award in 2015. Dr. Hametz is board certified by the American Board of Pediatrics and is a Resident Member of the American Academy of Pediatrics.</p>
Barry J. Fomberstein
<p>Dr. Barry J. Fomberstein is Associate Professor of Clinical Medicine (Rheumatology) at Albert Einstein College of Medicine and a practicing rheumatologist at Montefiore Medical Center. He graduated from Albert Einstein College of Medicine in 1976, and did his residency and fellowship at Long Island Jewish Medical Center.</p>
<p>Prior to arriving at Our Lady of Mercy Medical Center in 1992, Dr. Fomberstein was a full-time attending for nine years in the Department of Medicine at St John’s Episcopal Hospital in Far Rockaway, where he first became actively involved in the process of residency training. He is a fellow of the American College of Physicians (FACP), as well as a fellow of the American College of Rheumatology (FACR).</p>
Celina Crisman
Neurosurgical oncology and focuses on the diagnosis and surgical treatment of cranial lesions in adult patients
<p>Celina Crisman , MD, MPH, is an attending physician and Assistant Professor, Neurological Surgery at Montefiore Einstein. Dr. Crisman specializes in neurosurgical oncology and focuses on the diagnosis and surgical treatment of cranial lesions in adult patients. Through a dedicated fellowship, she received specialized training in surgical approaches to benign and malignant cranial tumors and enjoys applying the most advanced techniques and surgical adjuncts to each case. Dr. Crisman performs awake tumor resection when indicated and works closely with a multidisciplinary team to maximize resection of tumors in eloquent regions. She also cares for patients with general neurosurgical needs ranging from hydrocephalus, chiari malformation and herniated discs, as well as traumatic bleeds.</p><p>Dr. Crisman obtained her Bachelor of Science in biology and biology and society from Cornell University, and earned her Doctor of Medicine from Columbia University Valegos College of Physicians and Surgeons. She completed her residency in neurological surgery at Rutgers University and was a neurosurgical oncology fellow at Memorial Sloan Kettering. Dr. Crisman also earned a Masters in Public Health from the Harvard Chan School of Public Health.</p>
Bibi Ayesha
<p style="line-height: 15.75pt; margin: 0in 0in 7.5pt 0in;"><span style="font-size: 14.0pt; font-family: 'Calibri Light',sans-serif; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin; mso-bidi-theme-font: major-latin; color: #202020;">Bibi Ayesha has r<span style="font-size: 14pt; color: black;">eceived her medical degree from M.R. Medical College, India. She</span></span> completed her Internal Medicine training at Bronx Care Medical System/Ichan School of Medicine Mount Sinai and did her advanced Rheumatology training at the University of Iowa Hospital & Clinics (UIHC), in Iowa City, a leading center for HLH & vasculitis training and research. She joined Montefiore in 2017 and currently serves as the associate Program Director of Rheumatology Fellowship </p>
<p style="margin: 0in 0in 7.5pt; line-height: 150%;"><span style="font-size: 14.0pt; font-family: 'Calibri Light',sans-serif; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin; mso-bidi-theme-font: major-latin; color: #373a3c; background: #FEFEFE;">She is Director of Vasculitis Clinic, </span><span style="white-space: pre-wrap;"><span style="font-size: 14.0pt; font-family: 'Calibri Light',sans-serif; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin; mso-bidi-theme-font: major-latin; color: #202020;">which is a multidisciplinary collaborative effort taking care of complicated patients with vasculitic diseases, ophthalmic manifestations of rheumatic diseases and cancer immunotherapy related adverse autoimmune events. </span></span></p>
<p style="margin: 0in 0in 7.5pt; line-height: 150%;"><span style="font-size: 14.0pt; font-family: 'Calibri Light',sans-serif; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin; mso-bidi-theme-font: major-latin; color: #373a3c; background: #FEFEFE;">She is a member of the American College of Rheumatology and the Society of Immunotherapy for Cancer, a national organization dedicated to research, awareness, and treatment of Cancer and Immunotherapy related adverse events.</span></p>
<p><span style="font-size: 14.0pt; font-family: 'Calibri Light',sans-serif; mso-ascii-theme-font: major-latin; mso-hansi-theme-font: major-latin; mso-bidi-theme-font: major-latin; color: #373a3c;">She has been managing patients with HLH and currently leads the COVID-19 cytokine Task force at Montefiore Medical Center, a multidisciplinary team providing consensus recommendations for COVID-19 cytokine storm syndrome.</span></p>
<p> </p>
Cancer immunotherapy related adverse events
Ophthalmologic manifestation of autoimmune diseases
HLH/ Cytokine storm syndrome
Autoimmune occular disorders
Elizabeth M. Alderman
<p>Elizabeth M. Alderman, MD, a nationally recognized specialist in adolescent medicine, is Professor of Pediatrics and Obstetrics & Gynecology and Women’s Health at the Children’s Hospital at Montefiore, Albert Einstein College of Medicine. Dr. Alderman is the Chief, Division of Adolescent Medicine at the Children’s Hospital at Montefiore. She is currently the Program Director of the Post-doctoral fellowship in Adolescent Medicine and is past Program Director of the Pediatric Residency Program. Dr. Alderman is founder of the Montefiore Adolescent Primary Care Initiative.</p>
<p>Dr. Alderman received her BS, with honors, from Cornell University and MD with Distinction in Research from the State University of New York at Stony Brook Medical School where she was selected for membership to Alpha Phi Omega medical honors society. Dr. Alderman completed her pediatrics residency and adolescent medicine fellowship at the Albert Einstein College of Medicine/ Montefiore Medical Center.</p>
<p>She joined the pediatric faculty at Einstein/Montefiore upon completion of her fellowship in 1992 and has remained throughout her career, achieving promotion to professor in 2003. </p>
<p>Dr. Alderman is the Co-chairperson of the AAP Council of Adolescent and Young Adult Health. She was Chair of the AAP Committee on Adolescence for 4 years and was previously a member of for the 6 years. She served as Chairperson of the AAP Section of Adolescent Health Executive Committee from 2008-2012. As a member of AAP NY Chapter 3 Executive Council for over 25 years, she has served as chair of the Committee on Adolescence and on its Executive Committee. She is a past-president of the North American Society of Pediatric and Adolescent Gynecology and former Member at Large of the Board of Directors for the Society for Adolescent Health and Medicine. Dr. Alderman has been a leader or panelist on many national initiatives related to adolescent health. </p>
<p>Dr. Alderman’s clinical interests include care for adolescents with heavy menstrual bleeding, contraception for adolescents with chronic illness, menstrual disorders, eating disorders and overall adolescent sexual health. She is co-editor of the AAP Textbook of Adolescent Health Care. Dr. Alderman has authored 65 research papers, review articles and chapters. She has presented over 40 abstracts at national meetings and delivered over 50 lectures and workshops in the past 5 years at regional and national meetings.</p>
<p>Dr. Alderman is known nationally and throughout the region as an outstanding clinician and she is regularly named to the “Best Doctors in New York” and “New York Super Doctors” lists. In 2003, the American Academy of Pediatrics recognized her with a Special Achievement Award from the New York Chapter for promoting adolescent health. </p>
Adolescent gynecology, menstrual disorders, reproductive health services for adolescents with chronic illness, eating disorders
Adolescent gynecology, menstrual disorders, reproductive health services for adolescents with chronic illness, eating disorders; Research Emphasis: Health care delivery for adolescents
<p><em><strong>FOR RECENT PEER REVIEWED PUBLICATIONS AND POLICY STATEMENTS AUTHORED, PLEASE SEARCH PUBMED</strong></em></p>
<p><strong><em>SELECTED BOOKS, CHAPTERS AND ABSTRACTS</em></strong></p>
<p><strong>Book Editor</strong></p>
<ol>
<li>S.B. Friedman,<strong> E.M. Alderman</strong>, R.H. Pantell, C.S. Saylor, M. Sugar, Monograph: Psychosocial Issues for Children and Families in Disasters. A Guide for the Primary Care Physician, U.S. Department of Health and Human Services, 1995. </li>
<li>S.B. Friedman, M. Fisher, S.K. Schonberg, <strong>E.M. Alderman</strong> ed. Book<em>: Comprehensive Adolescent Health Care</em>, 2nd edition, Mosby, Philadelphia, 1997</li>
<li>Medical Editor, emedicine, Pediatric Online Textbook</li>
<li><strong>E.M. Alderman, </strong>R.T. Brown, Book: Adolescents, Families and Society in the New Millennium<em> Adolescent Medicine State of the Art Reviews</em> 12:3, Hanley and Belfus, Inc. 2001</li>
<li>M. Fisher, E.M. Alderman, R. Kreipe, W. Rosenfeld eds. Book:Textbook of Adolescent Health Care, American Academy of Pediatrics, Elk Grove Village, IL, 2011. <strong>Exel Award Winner, Silver, Technical Book, Assoiciation Media and Publishing.</strong></li>
</ol>
<p><strong>Chapters in Text Books-Past 10 years</strong></p>
<ol>
<li>Maslyanskya, S, <strong>Alderman, EM. </strong>Yeast/Candida. In <em>Pediatric and Adolescent Gynecology</em>Ed. Paula Hillard, Wiley-Blackwell, Oxford, UK, 2013</li>
<li>Scott, NL, <strong>Alderman, EM.</strong> Case of a Girl with a Secret. In <em>Adolescent Gynecology: A Clinical Casebook,</em> ed. Talib, HJ, New York, NY, Springer Science+Business Media, 2017</li>
<li>Hollman, D, <strong>Alderman, EM</strong>, Ciorciari, AJ, Gynecologic Emergencies. In Gershel, JC, Crain, EF. <em>Clinical Manual of Emergency Pediatrics</em>. Cambridge, UK, Cambridge Univ. Press 2018; 312-348</li>
<li>Alderman, EM, Forward In: Adolescent Health: A Compendium of AAP Clinical Practice Guidelines and Policies, American Academy of Pediatrics, Elk Grove Village. April, 2020</li>
<li>Menezes, M., Alderman, E. Abnormal uterine bleeding in the adolescent. In Bonnie Halpern-Felsher (Ed), Encyclopedia of Child and Adolescent Health. New York, NY, Elsevier 2021. </li>
<li>Alderman, EM. Reproductive health care. Commentary. In American Academy of Pediatrics. Pediatrics Collections. Adolescent Health Care, American Academy of Pediatrics, Itasca, IL, 2023</li>
<li>Stager, M. Alderman, EM. Transition of care. Commentary. In American Academy of Pediatrics. Pediatrics Collections. Adolescent Health Care, American Academy of Pediatrics, Itasca, IL, 2023</li>
</ol>
<p><strong>Abstracts Presented at National and International Meetings in Past 10 Years</strong></p>
<ol>
<li> <strong>Alderman, </strong>EM<strong>, </strong>Goodfriend, G, Silverman, M, Freeman, K, Izes, J, Lobach, KSThen and Now: Changes in Adolescent Quality Indicators at 3 Community Health Centers After 5 YearsPreented Pediatric Academic Societies Annual Meeting, May 2013, Washington, DC</li>
<li>McKee, MD, <strong>Alderman, EM</strong>, Briggs, RD, Mann, M, Kus, CA, Blank, AE, Meissner, P, York, DV, Patel, NR, Lechuga, C, Hoidal, KES, Racine, AD. Improving screening for sexual activity and STIs among adolescents in urban primary care: results of a learning collaborative approach to quality improvement, Presented at the Society for Adolescent Health and Medicine Meeting, March 2014, Austin, TX</li>
<li>Bentsiov, S, Talib, HJ, Silver, EJ, <strong>Alderman, EM</strong>. The role of adolescent medicine training in provision of confidential care in hospitalized adolescents. Presented at Pediatric Academic Societies Annual Meeting, May 2014, Vancouver, BC</li>
<li>Talib, HJ, Bentsiov, S, Silver, EJ, <strong>Alderman, EM</strong>. Challenges to adolescent confidentiality with family-centered rounds in a children’s hospital. Presented at Pediatric Academic Societies Annual Meeting, May 2014, Vancouver, BC</li>
<li><strong>Alderman, EM</strong>, Freeman, KI, Burton, WB, Izes, JM, Lobach, KS. Seeking health care on their own: the experience of teen patients in three urban community health centers. Presented at Pediatric Academic Societies Annual Meeting, May 2014, Vancouver, BC</li>
<li>Proper, C, Wren, SB, Goldman, DL, <strong>Alderman, E</strong>, Khine, H Risk Factors for Sexually Transmitted Infection in Patients Seeking Emergency Psychiatric Evaluation in the Pediatric Emergency Department. Presented at Eastern Society for Pediatric Research, March 2016, Philadelphia, PA Pediatric Academic Societies Annual Meeting, May 2016, Baltimore, MD</li>
<li>Shah, Ami, Sung, D, Waltuch, T, <strong>Alderman, E,</strong> Dadlez, NM, Weingarten-Arams, J. Achieving high quality chest compressions with deliberate practice in a pediatric residency program. Presented at Society of Critical Care Medicine-48thCritical Care Congress, February, 2019, San Diego, CA and Pediatric Academic Societies Annual Meeting, May, 2019, Baltimore, MD.</li>
<li>Bochner, R, Duh-Leong, C, Durstenfeld, A, Rabin, M, Broder, M, <strong>Alderman, E</strong>, Acholonu, R, McCabe, M The PRICE is right: The impact of the pediatric residents improving cost effectiveness (PRICE) workshop. Presented at Pediatric Academic Societies Annual Meeting , May, 2019, Baltimore, MD and at the Architecture of High Value Healthcare National Conference, November 2019, Baltimore, MD</li>
<li>Schulte, EE, Alderman, E, Feldman, JM, Hametz, P, Havrenek, T, Kaskel, R, Levy, A, Manwani, D, Stein, R. Using the coach approach: a novel peer mentorship program for physicians. Accepted to AAMC 2020 GFA Professional Development Conference (Due to COVID-19 related conference cancellation, this peer reviewed abstract was accepted but not presented) </li>
<li>Schulte, EE, Alderman, E, Feldman, JM, Hametz, P, Havrenek, T, Kaskel, R, Levy, A, Manwani, D, Stein, R. Using the coach approach: a novel peer mentorship program for physicians. Presented at the Pediatrics Academic Societies Annual Meeting. May, 2021, Virtual Meeting</li>
</ol>
<p>Elizabeth M. Alderman, MD, FAAP, FSAHM, is Chief of the Division of Adolescent Medicine at Children’s Hospital at Montefiore (CHAM). She is also a Professor of Pediatrics and Obstetrics & Gynecology and Women’s Health at our Albert Einstein College of Medicine. Dr. Alderman’s clinical focuses are on office gynecology, including a special practice for girls with heavy menstrual bleeding or abnormal vaginal bleeding, as well as the medical management of eating disorders. Her clinical expertise also includes reproductive health for both adolescent boys and girls. She joined the Montefiore team as faculty in 1992.</p><p>Dr. Alderman received her Bachelor of Science with Honors, from Cornell University, College of Agriculture and Life Science in 1983. She then went on to receive her Doctor of Medicine degree with Distinction in Research, from State University of New York at Stony Book in 1987. Dr. Alderman began a residency in Pediatrics in 1987, followed by a postdoctoral fellowship in Adolescent Medicine at Montefiore and Einstein. </p><p>Dr. Alderman’s research interests focus on quality improvement in the delivery of adolescent health care and health screening. She has published research on sexually transmitted infections and adolescent gynecology.</p><p>Dr. Alderman has been a recipient of numerous awards for her clinical work and research. In 2013, she received the Adele Dellenbaugh Hoffman Award for excellence in adolescent medicine, given by the American Academy of Pediatrics.</p><p>Dr. Alderman is board certified by the American Board of Pediatrics and is a member of many professional societies, including the American Academy of Pediatrics, where she is currently the Chair of the Committee of Adolescence and past chairperson of the Section of Adolescent Health Executive Committee, the Society for Adolescent Medicine, as a former Executive Board member and the North American Society for Pediatric and Adolescent Gynecology of which she was past president.</p>