Jose M. Taveras
Nicole J. Sutton
Pulmonary Hypertension
Single Ventricle
Radiation Safety
Quality Improvement
<p>Nicole Jampol Sutton, MD, is Division Chief, Pediatric Cardiology, Director, Invasive Cardiology, Director, Pediatric Pulmonary Hypertension Program, and Interim Codirector, Pediatric Heart Center at Children’s Hospital at Montefiore. She is also an Associate Professor of Pediatrics at Montefiore-Einstein. Dr. Sutton’s clinical focus is on congenital heart disease, pediatric interventional cardiology, pediatric pulmonary hypertension and adult congenital heart disease.</p><p>After receiving her Bachelor of Arts from Harvard University in 1994, Dr. Sutton attended New York University Medical School, earning her Doctor of Medicine in 1998. She began her postdoctoral training with a three-year pediatric residency at NewYork-Presbyterian Morgan Stanley Children’s Hospital, which she completed in 2001. She followed this with a cardiology fellowship at Boston Children’s Hospital, acting as Chief Cardiology Fellow in 2004 and Senior Catheterization Fellow in 2005.</p><p>Dr. Sutton’s research focuses on improving interventional techniques and on quality improvement in the cardiac catheterization lab, including radiation safety. She is also involved in several clinical trials of medications for the treatment of pulmonary hypertension. Her work has been published in many peer-reviewed journals, books and abstracts. Dr. Sutton is a reviewer for several journals including the <em>American Journal of Cardiology</em>, <em>Pediatric Cardiology</em> and <em>Cardiology in the Young</em>.</p><p>Dr. Sutton is board certified in pediatrics, pediatric cardiology and adult congenital heart disease. She is a member of several professional societies including the American Academy of Pediatrics, the American College of Cardiology and the Society of Cardiac Angiography and Intervention. In 2005, she was winner of the poster competition in clinical science at the American Heart Association Scientific Sessions. </p>
Sarah Sungurlu
Asli S. Sucu
Michael B. Stemerman
<p>Most people in the USA die of cardiovascular disease. A major risk factor for heart attacks is elevated cholesterol, especially the cholesterol carried by low density lipoprotein (LDL). Our studies examine the hypothesis that LDL alters the function of the vascular endothelium and this alteration may be an important mechanism for the development of atherosclerosis. Of particular focus is our understanding of the molecular mechanisms involved in this process and the role mononuclear cells play in their interaction with the LDL treated vascular endothelium.</p>
<p><a target="_blank" href="http://biomed.ucr.edu/content/view/69/66/">Dr. Stemerman's Laboratory and Researchers</a></p>
<p>Liu, Y., Chen, B.P., Lu, M., Zhu, Y., Stemerman, M.B., Chien, S. and Shyy, J.Y. 2002. Shear stress activation of SREBP1 in endothelial cells is mediated by integrins. Arterioscler. Thromb. Vasc. Biol. 22: 76-81.<br />
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Yuan, Y., Verna, L.K., Wang, N.P., Liao, H.L., Ma, K.S., Wang, Y., Zhu, Y. and Stemerman M.B. 2001. Cholesterol enrichment upregulates intercellular adhesion molecule-1 in human vascular endothelial cells. Biochim. Biophys. Acta. 1534: 139-48.<br />
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Wang, N., Verna, L., Liao, H.L., Ballard, A., Zhu, Y. and Stemerman, M.B. 2001. Adenovirus-mediated overexpression of dominant-negative mutant of c-Jun prevents intercellular adhesion molecule-1 induction by LDL: a critical role for activator protein-1 in endothelial activation. Arterioscler. Thromb. Vasc. Biol. 21: 1414-20.<br />
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Wang, N. and Stemerman, M.B. 2001. Ref-1 and transcriptional control of endothelial apoptosis. Circulation Res. 88: 1223-1225.<br />
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Zhu, Y., Liao, H-L, Wang, N., Ma, K-S., Verna, L.K., Shyy, Y-J., Chien, S. and Stemerman, M.B. 2001. LDL-Activated p38 in Endothelial Cells is Mediated by Ras. Arteriosclerosis Thromb. Vasc. Biol. 21: 1159-1164.<br />
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Stemerman, M.B. 2000. Lipoprotein effects on the vessel wall. Circ. Res. 86: 715-716. Review<br />
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Liao, H.L., Zhu, Y., Wang, N., Verna, L. and Stemerman, M.B. 2000. Selective activation of endothelial cells by the antioxidant pyrrolidine dithiocarbamate: involvement of c-Jun and Jun N-terminal kinase activation. Endothelium 7: 121-33.<br />
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Wang, N., Verna, L., Hardy, S., Zhu, Y., Ma, K-S., Birrer, M.J. and Stemerman, M.B. 1999. c-Jun triggers apoptosis in human vascular endothelial cells. Circ. Res. 85: 387-393.<br />
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Wang, N.P., Verna, L., Hardy, S., Forsayeth, J., Zhu, Y. and Stemerman, M.B. 1999. Adenovirus-mediated overexpression of c-Jun and c-Fos induces intercellular adhesion molecule-1 and monocyte chemoattractant protein-1 in human endothelial cells. Arterio. Thromb. Vasc. Biol. 19: 2078-2084.<br />
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Zhu, Y., Liao, H.L., Lin, H.-C., Verna, L. and Stemerman, M.B. 1999. Low-density lipoprotein augments interleukin-1-induced vascular adhesion molecule expression in human endothelial cells. Atherosclerosis 144: 357-365.<br />
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Zhu, Y., Liao, H.L., Wang, N.P., Friedli, O., Verna, L. and Stemerman, M.B. 1999. Low density lipoprotein activates Jun N-terminal kinase (JNK) in human endothelial cells. Biochimica et Biophysica Acta 1436: 557-564.<br />
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Zhu, Y., Lin, J.H.C., Liao, H.-L., Friedli, O., Verna, L., Marten, N.W., Straus, D.S. and Stemerman, M.B. 1998. Low-density lipoprotein induces transcription factor activator protein-1 (AP-1) in human endothelial cells. Arterio. Thromb. Vasc. Biol. 18: 473-470.<br />
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Zhu, Y., Lin, H.-C., Liao, H.L., Verna, L. and Stemerman, M.B. 1997. Activation of ICAM-1 promoter by lysophosphatidylcholine: Possible involvement of protein tyrosine kinases. Biochimica et Biophysica Acta 1345: 93-98.</p>
Kate R. Steinberg
Martina Stehlikova
<p>In-patient internal medicine with a special interest in hematology. Anemia, thrombocytopenia and coagulopathy in hospitalised patients.</p>
Tihomir Stefanec
<p>I am interested in Internal Medicine, Critical Care Medicine and Pulmonary Medicine. My current interest is Critical Care Medicine. </p>
Multidisciplinary Critical Care Medicine (Medical, Surgical, Neurologic, Cardiothoracic).<quillbot-extension-portal></quillbot-extension-portal>
Role of the endothelium and its progenitors in the pathogenesis of disease.<quillbot-extension-portal></quillbot-extension-portal>
<p>Tihomir Stefanec, MD, is Attending Physician, Critical Care Medicine, Assistant Professor, Medicine and Neurology at Montefiore Einstein. His clinical focus is multidisciplinary critical care medicine including medical, surgical, neurologic and cardiothoracic critical care.</p><p>After earning his Doctor of Medicine from the University of Zagreb Medical School in Zagreb, Croatia in 1992, Dr. Stefanec completed an internal medicine internship and residency at Long Island College Hospital in 1997. He then completed a critical care medicine fellowship at Saint Vincent’s Hospital and Medical Center in 1999. Following this, Dr. Stefanec completed a pulmonary medicine fellowship at Memorial Sloan Kettering Cancer Center in 2001.</p><p>Dr. Stefanec’s past research focuses on the role of the endothelium and its progenitors in the pathogenesis of disease. His work has been published in peer-reviewed original publications, reviews, editorials and abstracts, and he has presented nationally.</p><p>Dr. Stefanec is board certified in Internal Medicine, Critical Care Medicine and Pulmonary Medicine by the American Board of Internal Medicine, as well as in Neurocritical Care by the United Council for Neurologic Subspecialties. He has been a Fellow of the American College of Chest Physicians since 2003, and is a member of the American Thoracic Society, the American College of Chest Physicians and the European Respiratory Society.</p>