Manoj Lal Karwa
Sanjeev Gupta
<p>Liver regeneration is critical for health. We focus on physiology of liver regeneration during development, early childhood and adulthood to inform mechanistic disruptions in diseases. The latter ranges from acute liver failure, effects of drugs, toxins, alcohol, virus hepatitis, obesity-related metabolic (or nonalcoholic) liver disease, chronic hepatitis, e.g., Wilson disease with copper toxicosis, and allograft rejection. The mechanisms concerning DNA damage response directed by ATM gene and downstream partners are of considerable interest to us. </p>
<p>These aspects are joined with study of cell type-specific contributions as well as aspects of stem cell biology for liver regeneration. We apply cell transplantation approaches to better understand the biology and regenerative potential of various cell types. Expression of therapeutic constructs and transplantation of those cells is another area of investigative interest. We address the role of endogenous stem/progenitor cells in therapeutic development. Tissue engineering to generate auxiliary liver has potential in these areas and is also advancing liver regenerartion in experimental models.</p>
<p>We use a variety of methods, including microarrays or deep sequencing for gene expression, cell and molecular biology methods, and multiple small and large animal models. The findings are integrated with analyses of human tissue and blood samples.</p>
<p>Unique aspects of our work include use of established drugs for mechanistic interrogations and therapeutic applications, and an uncommon depth and breadth of multidisciplinary tools. We collaborate with leading investigators at Einstein or elsewhere as appropriate.</p>
Biology and differentiation of hepatic stem cells
DNA damage response involving ATM and downstream pathways
Translational studies using liver cell and animal models
Therapeutics including cell and gene therapy
<p class="MsoNormal" style="line-height: 15.6pt;"><span style="font-size: 9.0pt;">Dr. Gupta is a pioneer in the development of cell therapy – treating disease by introducing healthy cells into the body. He has discovered various mechanisms for coaxing transplanted cells to attach to host tissue and multiply, paving the way for treating health problems such as high cholesterol, hemophilia, liver failure, and hepatitis. </span></p>
<p class="MsoNormal" style="line-height: 15.6pt;"><span style="font-size: 9.0pt;">Dr. Gupta has successfully manipulated human stem cells to generate liver cells and defined some of the fundamental ways by which gene expression is regulated in stem cells. Dr. Gupta serves as an expert for the National Institutes of Health, U.S. Department of Veterans Affairs, U.S. Department of Defense, Wellcome Trust, and national scientific bodies in over ten countries.</span></p>
<p class="MsoNormal" style="line-height: 15.6pt;"><span style="font-size: 9.0pt;">In the 1990s, Dr. Gupta contributed to the first ever clinical trial of a cell/gene therapy for familial hypercholesterolemia (high cholesterol), which results from a gene defect. He also showed that Wilson’s disease (a genetic condition characterized by excessive accumulation of copper in the liver and brain) could potentially be cured by use of cell therapy. </span></p>
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<ul type="disc">
<li>Thirunavukkarasu C, Sharma Y, Tchaikovskaya T, Maslov AY, Gupta S. Transcriptional profiling reveals ataxia telangiectasia mutated pathways regulate joint copper and arsenic toxicity for hepatic metalloplasia and anti-cancer therapies. Life Sci. 2022 Jul 6;120787. doi: 10.1016/j.lfs.2022.120787. </li>
<li>Chang CJ, Ge EJ Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou Q, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, Ralle M, Schilsky ML, Tonks NK, Vahdat LK, Van Aelst L, Xi D, Yuan P, Brady DC. Connecting copper and cancer from transition metal signaling to metalloplasia in the clinic. Nat Rev Cancer 2022 Feb;22(2):102-113. doi: 10.1038/s41568-021-00417-2. Epub 2021 Nov 11. PMID: 34764459</li>
<li>Viswanathan P, Gupta P, Sharma Y, Maisuradze L, Bandi S, Gupta S. Caffeine disrupts ataxia telangiectasia mutated gene-related pathways and exacerbates acetaminophen toxicity in human fetal immortalized hepatocytes. Toxicology. 2021 May 7;457:152811. doi: 10.1016/j.tox.2021.152811. PMID: 33971260</li>
<li>Viswanathan P, Sharma Y, Jaber FL, Tchaikovskaya T, Gupta S. Transplanted hepatocytes rescue mice in acetaminophen-induced acute liver failure through paracrine signals for hepatic ATM and STAT3 pathways. FASEB J 2021 Apr;35(4):e21471. doi: 10.1096/fj.202002421R. PMID: 33683737</li>
<li>Jaber FL, Sharma Y, Mui BG, Kapoor S, Gupta S. Tumor necrosis factor directs allograft-related innate responses and its neutralization improves hepatocyte engraftment in rats. Am J Pathol 2021; 191(1):79-89. doi: 10.1016/j.ajpath.2020.09.014. Epub 2020 Oct 27. PMID: 33127336</li>
<li>Viswanathan P, Sharma Y, Gupta S. Ataxia telangiectasia mutated pathway disruption affects hepatic DNA and tissue damage in nonalcoholic fatty liver disease. Exp Mol Pathol. 2020 Apr; 113:104369. doi: 10.1016/j.yexmp.2020.104369. Epub 2020 Jan 7. PMID: 31917286</li>
<li>Gupta P, Sharma Y, Viswanathan P, Gupta S. Cellular receptor signaling and ATM pathway intersections regulate hepatic DNA repair. Cytokine 2020 Mar; 127:154946. doi: 10.1016/j.cyto.2019.154946. Epub 2019 Dec 11. PMID: 31837586</li>
<li>Bandi S, Tchaikovskaya T, Gupta S. Hepatic differentiation in human pluripotent stem cells by developmental stage-specific metabolomics products. Differentiation 2019; 105:54-70. Jan 28;105:54-70. doi: 10.1016/j.diff.2019.01.005. PMID: 30776728.</li>
<li>Kakabadze Z, Karalashvili L, Chakhunashvili D, Havlioglu N, Janelidze M, Kakabadze A, Sharma Y, Gupta S. Decellularized bovine placentome for portacavally-interposed heterotopic liver transplantation in rats. Mater Sci Eng C Mater Biol Appl. 2019 Apr; 97:293-301. doi: 10.1016/j.msec.2018.12.025. Epub 2018 Dec 10. PMID: 30678914.</li>
<li>Yadav N, Jaber FL, Sharma Y, Viswanathan P, Gupta S. Efficient reconstitution of hepatic microvasculature by endothelin receptor antagonism in liver sinusoidal endothelial cells. Hum Gene Ther 2018; Sep 28. doi: 10.1089/hum.2018.166. PMID: 30266073, </li>
<li>Sharma Y, Liu J, Kristian KE, Follenzi A, Gupta S. In Atp7b-/- mice modeling Wilson's disease liver repopulation with bone marrow-derived myofibroblasts or inflammatory cells and not hepatocytes is delterious. <span title="Gene expression">Gene Expr</span>. 2018 Jul 20. doi: 10.3727/105221618X15320123457380. PMID: 30029699</li>
<li>Bandi S, Gupta S, Tchaikovskaya T, Gupta S. Differentiation in stem/progenitor cells along fetal or adult hepatic stages requires transcriptional regulators independently of oscillations in microRNA expression. <span title="Experimental cell research">Exp Cell Res</span>. 2018 Sep 1;370(1):1-12. doi: 10.1016/j.yexcr.2018.06.004. Epub 2018 Jun 6.</li>
<li>Benten D, Kluwe J, Wirth JW, Thiele ND, Follenzi A, Bhargava KK, Palestro CJ, Koepke M, Tjandra R, Volz T, Lutgehetmann M, Gupta S. A humanized mouse model with liver fibrosis following expansion of transplanted hepatic stellate cells in injury and inflammation. Lab Invest 2018 Apr;98(4):525-536. doi: 10.1038/s41374-017-0010-7. Epub 2018 Jan 19.PMID: 29352225.</li>
<li>Viswanathan P, Sharma Y, Gupta P, Gupta S. Replicative stress and alterations in cell cycle checkpoint controls following acetaminophen hepatotoxicity restrict hepatic regeneration. Cell Prolif 2018; Jun;51(3):e12445. doi: 10.1111/cpr.12445. Epub 2018 Mar 5. PMID: 29504225.</li>
<li>Kakabadze Z, Kakabadze A, Chakhunashvili D, Karalashvili L, Berishvili E, Sharma Y, Gupta S. Decellularized human placenta supports hepatic tissue and allows rescue in acute liver failure. Hepatology 2018 May;67(5):1956-1969. PMID: 29211918. </li>
</ul>
Benjamin T. Galen
<p>Dr. Galen graduated from Brown University with honors in the biological sciences and earned an M.D. from Tufts University School of Medicine. He trained in internal medicine at Yale University where he was elected to the Gold Humanism Honor Society and was the class speaker at residency graduation. He joined Montefiore and Einstein in 2013 as a teaching attending in Hospital Medicine</p>
<p>Dr. Galen is an Associate Program Director in The Einstein/Montefiore Internal Medicine Residency Program, the Director of Firm 3 and the Director of ultrasound and procedure training. In 2015 Dr. Galen received the Sharon R. Silbiger Faculty Teaching Award from the Einstein residents. He has led hundreds of resident teaching conferences and has worked to formalize curricula for point-of-care ultrasound (POCUS) and bedside procedures, such as lumbar puncture and paracentesis. Dr. Galen has taught in the EPHEM, Microbiology, and PDC classes at Einstein. He has led translational research on recurrent meningitis, collaborting with members of Betsy Herold's laboratory. He has co-authored over 20 original research studies. Dr. Galen is passionate about medical case reports and he has mentored residents and junior faculty in the process of publishing cases in a variety of venues. </p>
<p>Dr. Galen is the editor-in-chief of <em>POCUS Journal (</em><a href="https://pocusjournal.com/">https://pocusjournal.com/)</a>, the world's leading peer-reviewed, open-access publication for point-of-care ultrasound. He teaches POCUS nationally at a variety of workshops and conferences. </p>
<ol>
<li>Shankar, N., Kuo, L., Krugliak Cleveland, N., Galen, B., Samel, N. S., Perez-Sanchez, A., Nathanson, R., Coss, E., Echavarria, J., Rubin, D. T., & Soni, N. J. (2025). Point-of-Care Ultrasound in Gastroenterology and Hepatology. <em>Clin Gastroenterol Hepatol</em>. <a href="https://doi.org/10.1016/j.cgh.2024.09.040" target="_blank" rel="noopener noreferrer">https://doi.org/10.1016/j.cgh.2024.09.040</a></li>
<li>Cool, J. A., Galen, B. T., & Dancel, R. (2025). Point-counterpoint: Should hospitalists perform their own bedside procedures? <em>J Hosp Med</em>,<em> 20</em>(1), 89-93. <a href="https://doi.org/10.1002/jhm.13545" target="_blank" rel="noopener noreferrer">https://doi.org/10.1002/jhm.13545</a></li>
<li>Schechter, M. S., Baron, S. W., Gohari, A., Southern, W. N., & Galen, B. T. (2024). Midline Catheter-Associated Thrombosis (MCAT): Does Tip Location in the Axillary Vein Increase Risk? <em>J Infus Nurs</em>,<em> 47</em>(6), 363-368. <a href="https://doi.org/10.1097/nan.0000000000000558" target="_blank" rel="noopener noreferrer">https://doi.org/10.1097/nan.0000000000000558</a></li>
<li>Singh, J., Oliver-Krasinski, J., Tauras, J., & Galen, B. T. (2023). Systemic Amyloidosis: Is It ATTR or AL? <em>Am J Med</em>,<em> 136</em>(7), 652-654. <a href="https://doi.org/10.1016/j.amjmed.2023.03.009" target="_blank" rel="noopener noreferrer">https://doi.org/10.1016/j.amjmed.2023.03.009</a></li>
<li>Johri, A. M., Glass, C., Hill, B., Jensen, T., Puentes, W., Olusanya, O., Capizzano, J. N., Dancel, R., Reierson, K., Reisinger, N., Liblik, K., & Galen, B. T. (2023). The Evolution of Cardiovascular Ultrasound: A Review of Cardiac Point-of-Care Ultrasound (POCUS) Across Specialties. <em>Am J Med</em>,<em> 136</em>(7), 621-628. <a href="https://doi.org/10.1016/j.amjmed.2023.02.020" target="_blank" rel="noopener noreferrer">https://doi.org/10.1016/j.amjmed.2023.02.020</a></li>
<li>Eman, G., Synn, S., Galen, B., Shah, R., Nauka, P., Hope, A. A., Congdon, S., & Islam, M. (2023). Thoracic Ultrasound in COVID-19: Use of Lung and Diaphragm Ultrasound in Evaluating Dyspnea in Survivors of Acute Respiratory Distress Syndrome from COVID-19 Pneumonia in a Post-ICU Clinic. <em>Lung</em>,<em> 201</em>(2), 149-157. <a href="https://doi.org/10.1007/s00408-023-00614-w" target="_blank" rel="noopener noreferrer">https://doi.org/10.1007/s00408-023-00614-w</a></li>
<li>Nauka, P. C., LeFrancois, D., & Galen, B. T. (2022). An Introductory Curriculum for Internal Medicine Interns in Point-of-Care Ultrasound to Detect Lower Extremity Deep Vein Thrombosis. <em>Pocus j</em>,<em> 7</em>(2), 185-186. <a href="https://doi.org/10.24908/pocus.v7i2.15937" target="_blank" rel="noopener noreferrer">https://doi.org/10.24908/pocus.v7i2.15937</a></li>
<li>Varrias, D., Palaiodimos, L., Balasubramanian, P., Barrera, C. A., Nauka, P., Melainis, A. A., Zamora, C., Zavras, P., Napolitano, M., Gulani, P., Ntaios, G., Faillace, R. T., & Galen, B. (2021). The Use of Point-of-Care Ultrasound (POCUS) in the Diagnosis of Deep Vein Thrombosis. <em>J Clin Med</em>,<em> 10</em>(17). <a href="https://doi.org/10.3390/jcm10173903" target="_blank" rel="noopener noreferrer">https://doi.org/10.3390/jcm10173903</a></li>
<li>Shah, R., Zhang, L., & Galen, B. T. (2021). A 73-Year-Old Woman With Pulseless Electrical Activity Arrest. <em>Chest</em>,<em> 160</em>(6), e665-e667. <a href="https://doi.org/10.1016/j.chest.2021.03.075" target="_blank" rel="noopener noreferrer">https://doi.org/10.1016/j.chest.2021.03.075</a></li>
<li>Koleilat, I., Galen, B., Choinski, K., Hatch, A. N., Jones, D. B., Billett, H., Indes, J., & Lipsitz, E. (2021). Clinical characteristics of acute lower extremity deep venous thrombosis diagnosed by duplex in patients hospitalized for coronavirus disease 2019. <em>J Vasc Surg Venous Lymphat Disord</em>,<em> 9</em>(1), 36-46. <a href="https://doi.org/10.1016/j.jvsv.2020.06.012" target="_blank" rel="noopener noreferrer">https://doi.org/10.1016/j.jvsv.2020.06.012</a></li>
<li>Nauka, P. C., & Galen, B. T. (2020). The Focused Assessment with Sonography in Cancer (FASC) Examination. <em>Pocus j</em>,<em> 5</em>(2), 42-45. <a href="https://doi.org/10.24908/pocus.v5i2.14428" target="_blank" rel="noopener noreferrer">https://doi.org/10.24908/pocus.v5i2.14428</a></li>
<li>Merkin, R., Kruger, A., Bhardwaj, G., Kajita, G. R., Shapiro, L., & Galen, B. T. (2020). Internal Medicine Resident Work Absence During the COVID-19 Pandemic at a Large Academic Medical Center in New York City. <em>J Grad Med Educ</em>,<em> 12</em>(6), 682-685. <a href="https://doi.org/10.4300/jgme-d-20-00657.1" target="_blank" rel="noopener noreferrer">https://doi.org/10.4300/jgme-d-20-00657.1</a></li>
</ol>
Joseph D. Frager
<p>Dr. Frager specializes in disorders of the Colon and Upper GI Tract including: Colon Polyps, Diverticulitis, Peptic Ulcer Disease, Gastroesophageal Reflux and Gallstones.</p>
<p>Immunology of the GI Tract</p>
<p>Joseph Frager, MD, is an Attending Physician in Gastroenterology and Assistant Professor of Medicine at Montefiore Einstein. Dr. Frager specializes in the diagnosis and treatment of disorders of the colon and upper gastrointestinal tract including colon polyps, diverticulitis, peptic ulcer disease, gastroesophageal reflux and gallstones.</p><p>After earning his Doctor of Medicine from University of Pennsylvania School of Medicine in 1980, Dr. Frager came to Montefiore for his postgraduate training. He completed his internal medicine internship and residency in 1983, followed by his fellowship in gastroenterology in 1985.</p><p>Dr. Frager’s research focus is on the immunology of the gastrointestinal tract. He has shared his work through peer-reviewed journals and abstracts.</p><p>Dr. Frager is board certified in Internal Medicine by the American Board of Internal Medicine. He is a member of the American College of Gastroenterology, the American Gastroenterology Association and the New York Society for Gastrointestinal Endoscopy.</p>
Brett E. Fortune
<p>Brett E. Fortune, MD, MSc, is Medical Director, Liver Transplant Program, and Associate Professor, Medicine at Montefiore Einstein. His clinical focus centers on providing care for patients with advanced liver disease and those who need or have received liver transplantation.</p>
<p>After obtaining his Bachelor of Science in biological sciences in 1999 from North Carolina State University, Dr. Fortune earned his Doctor of Medicine from Wake Forest University School of Medicine in 2004. He then completed an internship and residency in internal medicine at The Ohio State University Medical Center in 2007. After this, he participated in a gastroenterology fellowship at the University of Colorado Denver, where he also earned his Master of Science in clinical sciences, completing both in 2011. Dr. Fortune remained there for another year to participate in a transplant hepatology fellowship, which he completed in 2012.</p>
<p>Dr. Fortune’s research focuses on clinical outcomes related to cirrhosis and portal hypertension complications as well as quality improvement in the care of patients with cirrhosis or those who have received a liver transplant. His work has been published in numerous peer-reviewed journals or books. He is currently Associate Editor for Liver Transplantation and Liver Section Editor for Digestive Disease Interventions, and has sat on the editorial board for Hepatology.</p>
<p>Dr. Fortune is board certified in Internal Medicine, Gastroenterology and Transplant Hepatology by the American Board of Internal Medicine. He is a member of many professional organizations, such as the American Association for the Study of Liver Diseases (AASLD), the American Gastroenterology Association (AGA) and the American Liver Foundation. Dr. Fortune won the Kushlan Junior Faculty Award, Section of Digestive Diseases in 2015 and the Howard M. Spiro Digestive Disease Fellowship Teaching Award in 2016 from Yale School of Medicine.</p>
<p>Brett E. Fortune, MD, MSc, is Medical Director, Liver Transplant Program, and Associate Professor, Medicine at Montefiore Einstein. His clinical focus centers on providing care for patients with advanced liver disease and those who need or have received liver transplantation.</p><p>After obtaining his Bachelor of Science in biological sciences in 1999 from North Carolina State University, Dr. Fortune earned his Doctor of Medicine from Wake Forest University School of Medicine in 2004. He then completed an internship and residency in internal medicine at The Ohio State University Medical Center in 2007. After this, he participated in a gastroenterology fellowship at the University of Colorado Denver, where he also earned his Master of Science in clinical sciences, completing both in 2011. Dr. Fortune remained there for another year to participate in a transplant hepatology fellowship, which he completed in 2012.</p><p>Dr. Fortune’s research focuses on clinical outcomes related to cirrhosis and portal hypertension complications as well as quality improvement in the care of patients with cirrhosis or those who have received a liver transplant. His work has been published in numerous peer-reviewed journals or books. He is currently Associate Editor for <em>Liver Transplantation</em> and Liver Section Editor for <em>Digestive Disease Interventions</em>, and has sat on the editorial board for <em>Hepatology</em>.</p><p>Dr. Fortune is board certified in Internal Medicine, Gastroenterology and Transplant Hepatology by the American Board of Internal Medicine. He is a member of many professional organizations, such as the American Association for the Study of Liver Diseases (AASLD), the American Gastroenterology Association (AGA) and the American Liver Foundation. Dr. Fortune won the Kushlan Junior Faculty Award, Section of Digestive Diseases in 2015 and the Howard M. Spiro Digestive Disease Fellowship Teaching Award in 2016 from Yale School of Medicine.</p>
Antonio C. Fojas, Jr.
<p>Dr. Antonio Fojas obtained his MD from De La Salle University College of Medicine in the Philippines. He completed his residency in Internal Medicine at Our Lady of Mercy Medical Center in the Bronx and was a General Medicine Fellow and Chief Medical Resident at the same institution.</p><p>After completing his fellowship, Dr. Fojas was appointed Chief of General Medicine Ambulatory Clinic until 2003. Since December 2006 he has been an Associate Program Director of the Internal Medicine Program at Our lady of Mercy Medical Center and now Montefiore Medical Center-Wakefield Campus.</p><p>Dr. Fojas' major interest is Primary Care Medicine both in-patient and out-patient.</p>
Kristina R. Chacko
<p>Kristina R. Chacko, MD, is an Associate Professor of Medicine at the Albert Einstein College of Medicine in Bronx, NY. She joined the Einstein-Montefiore Liver Center in 2013 after completing a fellowship in Transplant Hepatology at Mount Sinai School of Medicine in New York, NY. She received her bachelor of arts in philosophy at Boston College and attended medical school at Baylor College of Medicine in Houston, TX. She completed her internal medicine residency at Emory University in Atlanta, GA, and gastroenterology fellowship at New York University. Her clinical and research interests include the diagnosis and management of alcoholic hepatitis, non-alcoholic fatty liver disease, autoimmune liver diseases, and liver transplantation. As the program director of the ACGME-accredited transplant hepatology fellowship at Montefiore Medical Center, she is directly involved in the development and execution of the hepatology curriculum for gastroenterology and hepatology fellows. </p>
<p><span style="color:#616161;font-family:'SF Pro Text', 'Segoe UI', 'Segoe WP', Tahoma, Arial, sans-serif, Roboto;font-size:14px;letter-spacing:-0.24px;background-color:#f5f5f5;">Transplant Hepatology, Autoimmune Hepatitis, Fatty Liver Disease (Alcohol/Non-alcohol), Acute alcoholic hepatitis, Living Donor Transplant</span></p>
<span style="color:#616161;font-family:'SF Pro Text', 'Segoe UI', 'Segoe WP', Tahoma, Arial, sans-serif, Roboto;font-size:14px;letter-spacing:-0.24px;background-color:#f5f5f5;">Research interest includes alcohol-related liver disease, liver transplantation, viral hepatitis and autoimmune liver disease.</span>
<p style="text-align: left;"><span style="color: #222222; font-family: Arial, sans-serif; font-size: 13px;"><span style="color: #212121; font-family: BlinkMacSystemFont, -apple-system, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Fira Sans', 'Droid Sans', 'Helvetica Neue', sans-serif; font-size: 16px;">Nahas J, Tow CY, <strong>Chacko KR</strong>, Haider T, Massoumi H. Granulocyte colony-stimulating factor does not improve mortality in severe alcoholic hepatitis: a single-center experience from the United States. Gastroenterol Hepatol Bed Bench. 2023;16(1):524-526. PMID: 37070107</span></span></p>
<p style="text-align: left;"><span style="color: #222222; font-family: Arial, sans-serif; font-size: 13px;"><span style="color: #212121; font-family: BlinkMacSystemFont, -apple-system, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Fira Sans', 'Droid Sans', 'Helvetica Neue', sans-serif; font-size: 16px;">Díaz LA, Fuentes-López E, Ayares G, Idalsoaga F, Arnold J, Valverde MA, Perez D, Gómez J, Escarate R, Villalón A, Ramírez CA, Hernandez-Tejero M, Zhang W, Qian S, Simonetto DA, Ahn JC, Buryska S, Dunn W, Mehta H, Agrawal R, Cabezas J, García-Carrera I, Cuyàs B, Poca M, Soriano G, Sarin SK, Maiwall R, Jalal PK, Abdulsada S, Higuera-de-la-Tijera F, Kulkarni AV, Rao PN, Salazar PG, Skladaný L, Bystrianska N, Clemente-Sanchez A, Villaseca-Gómez C, Haider T, <strong>Chacko KR</strong>, Romero GA, Pollarsky FD, Restrepo JC, Castro-Sanchez S, Toro LG, Yaquich P, Mendizabal M, Garrido ML, Marciano S, Dirchwolf M, Vargas V, Jiménez C, Louvet A, García-Tsao G, Roblero JP, Abraldes JG, Shah VH, Kamath PS, Arrese M, Singal AK, Bataller R, Arab JP. MELD 3.0 adequately predicts mortality and renal replacement therapy requirements in patients with alcohol-associated hepatitis. JHEP Rep. 2023 Mar 15;5(8):100727. PMID: 37456675; </span></span></p>
<p style="text-align: left;"><span style="color: #222222; font-family: Arial, sans-serif; font-size: 13px;"><span style="color: #212121; font-family: BlinkMacSystemFont, -apple-system, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Fira Sans', 'Droid Sans', 'Helvetica Neue', sans-serif; font-size: 16px;">Arab JP, Díaz LA, Baeza N, Idalsoaga F, Fuentes-López E, Arnold J, Ramírez CA, Morales-Arraez D, Ventura-Cots M, Alvarado-Tapias E, Zhang W, Clark V, Simonetto D, Ahn JC, Buryska S, Mehta TI, Stefanescu H, Horhat A, Bumbu A, Dunn W, Attar B, Agrawal R, Haque ZS, Majeed M, Cabezas J, García-Carrera I, Parker R, Cuyàs B, Poca M, Soriano G, Sarin SK, Maiwall R, Jalal PK, Abdulsada S, Higuera-de la Tijera MF, Kulkarni AV, Rao PN, Guerra Salazar P, Skladaný L, Bystrianska N, Prado V, Clemente-Sanchez A, Rincón D, Haider T, <strong>Chacko KR</strong>, Cairo F, de Sousa Coelho M, Romero GA, Pollarsky FD, Restrepo JC, Castro-Sanchez S, Toro LG, Yaquich P, Mendizabal M, Garrido ML, Narvaez A, Bessone F, Marcelo JS, Piombino D, Dirchwolf M, Arancibia JP, Altamirano J, Kim W, Araujo RC, Duarte-Rojo A, Vargas V, Rautou PE, Issoufaly T, Zamarripa F, Torre A, Lucey MR, Mathurin P, Louvet A, García-Tsao G, González JA, Verna E, Brown RS, Roblero JP, Abraldes JG, Arrese M, Shah VH, Kamath PS, Singal AK, Bataller R. Identification of optimal therapeutic window for steroid use in severe alcohol-associated hepatitis: A worldwide study. J Hepatol. 2021 Nov;75(5):1026-1033. doi: 10.1016/j.jhep.2021.06.019. Epub 2021 Jun 21. PMID: 34166722.</span></span></p>
<p style="text-align: left;"><span style="color: #222222; font-family: Arial, sans-serif; font-size: 13px;"><span style="color: #212121; font-family: BlinkMacSystemFont, -apple-system, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Fira Sans', 'Droid Sans', 'Helvetica Neue', sans-serif; font-size: 16px;">Andacoglu O, Özbek U, Liu J, Figueredo C, <strong>Chacko KR</strong>, Tow C, Reinus JF, Kinkhabwala M. Comparison of 1-Year Morbidity Following Liver Transplant for Acute Alcoholic Hepatitis Versus Alcoholic Cirrhosis. Exp Clin Transplant. 2021 May;19(5):439-444. Epub 2021 Jan 11. PMID: 33455569.</span></span></p>
<p style="text-align: left;"><span style="color: #212121; font-family: BlinkMacSystemFont, -apple-system, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Fira Sans', 'Droid Sans', 'Helvetica Neue', sans-serif; font-size: 16px;">Fontana RJ, Brown RS Jr, Moreno-Zamora A, Prieto M, Joshi S, Londoño MC, Herzer K, Chacko KR, Stauber RE, Knop V, Jafri SM, Castells L, Ferenci P, Torti C, Durand CM, Loiacono L, Lionetti R, Bahirwani R, Weiland O, Mubarak A, ElSharkawy AM, Stadler B, Montalbano M, Berg C, Pellicelli AM, Stenmark S, Vekeman F, Ionescu-Ittu R, Emond B, Reddy KR. Daclatasvir combined with sofosbuvir or simeprevir in liver transplant recipients with severe recurrent hepatitis C infection. Liver Transpl. 2016 Apr;22(4):446-58. PMID: 26890629.</span></p>
<p style="text-align: left;"><span style="color: #212121; font-family: BlinkMacSystemFont, -apple-system, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Fira Sans', 'Droid Sans', 'Helvetica Neue', sans-serif; font-size: 16px;"><strong>Chacko KR</strong>, Wolkoff AW. Intrahepatic Cholestasis of Pregnancy: New Diagnostic Insights. Ann Hepatol. 2017 March-April;16(2):176-178. PMID: 28233755.</span></p>
<p style="text-align: left;"><span style="color: #212121; font-family: BlinkMacSystemFont, -apple-system, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Fira Sans', 'Droid Sans', 'Helvetica Neue', sans-serif; font-size: 16px;"><strong>Chacko KR</strong>, Reinus J. Spectrum of Alcoholic Liver Disease. Clin Liver Dis. 2016 Aug;20(3):419-27. doi: 10.1016/j.cld.2016.02.002. Epub 2016 May 31. PMID: 27373606.</span></p>
<p style="text-align: left;"><span style="color: #212121; font-family: BlinkMacSystemFont, -apple-system, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Fira Sans', 'Droid Sans', 'Helvetica Neue', sans-serif; font-size: 16px;"><strong>Chacko KR</strong>, Reinus J. Extrahepatic Complications of Nonalcoholic Fatty Liver Disease. Clin Liver Dis. 2016 May;20(2):387-401. doi: 10.1016/j.cld.2015.10.004. Epub 2016 Feb 18. PMID: 27063276.</span></p>
James C.M. Brust
<p>Dr. Brust is a Professor of Medicine, with joint appointments in the Divisions of General Internal Medicine and Infectious Diseases. He graduated from the College of Physicians & Surgeons at Columbia University and completed both a residency in Internal Medicine and a fellowship in Infectious Diseases at the Columbia University Medical Center. </p>
<p>Dr. Brust's research is focused on the dual epidemics of multidrug-resistant tuberculosis (MDR TB) and HIV in South Africa. With multiple US and international collaborators, his multidisciplinary research group is studying treatment outcomes of MDR TB/HIV co-infected patients, transmission patterns of drug-resistant TB, pharmacology of new and repurposed TB medications, and genetic mechanisms of drug-resistance. He has funding from NIAID to examinine the emergence of resistance to the new TB medication bedaquiline in patients with MDR and XDR TB. </p>
<p><strong><strong>Selected Publications</strong></strong></p>
<p><strong><strong> </strong></strong></p>
<p><strong><strong>Brust JCM</strong></strong>, Gandhi NR, Carrara H, Osburn G and Padayatchi N. <em>High Treatment Failure and Default Rates for Patients with MDR TB in KwaZulu-Natal, South Africa, 2000-2003. </em>Int J Tuberc Lung Dis. 2010;14(4):413-9</p>
<p><strong> </strong></p>
<p><strong>Brust JCM</strong>, Shah NS, Scott M, Chaiyachati K, Lygizos M, van der Merwe TL, Bamber S, Radebe Z, Loveday M, Moll AP, Margot B, Lalloo UG, Friedland GH, Gandhi NR. <em>Integrated, home-based treatment for MDR-TB and HIV in rural South Africa: an alternate model of care</em>. Int J Tuberc Lung Dis 2012; 16:998-1004.</p>
<p><strong> </strong></p>
<p><strong>Brust JCM</strong>, Shah NS, van der Merwe TL, Bamber S, Ning Y, Heo M, Moll AP, Loveday M, Lalloo UG, Friedland GH, Gandhi NR. <em>Adverse events in an integrated, home-based treatment program for MDR-TB and HIV in KwaZulu-Natal, South Africa.</em> J Acquir Immune Defic Syndr 2013; 62:436-440.</p>
<p><strong> </strong></p>
<p><strong>Brust JCM</strong>, Berman AR, Zalta B, Haramati LB, Ning Y, Heo H, van der Merwe TL, Bamber S, Moll AP, Friedland GH, Shah NS, Gandhi NR.<em>Chest radiograph findings and time to culture conversion in patients with multidrug-resistant tuberculosis and HIV in Tugela Ferry, South Africa<strong>.</strong></em>PLoS One 2013; 8(9): e73975. doi:10.1371/journal.pone.0073975</p>
<p> </p>
<p>Gandhi NR, <strong>Brust JCM</strong>, Moodley P, Weissman D, Heo M, Ning Y, Moll AP, Friedland GH, Sturm W, Shah NS. <em>Low M. tuberculosis strain diversity among multidrug- and extensively drug-resistant tuberculosis isolates from Tugela Ferry, South Africa, 2005-2006</em>. Emerg Infect Dis 2014; 20(3):394-401.</p>
<p> </p>
<p>Loveday M, Wallengren K, <strong>Brust J</strong>, Roberts J, Voce A, Margot B, Ngozo J, Master I, Cassell G, Padayatchi N. <em>Community-based care vs. centralised hospitalisation for MDR-TB patients, KwaZulu-Natal, South Africa.</em> Int J Tuberc Lung Dis. 2015 Feb;19(2):163-71.</p>
<p> </p>
<p>Niehaus AJ, Gandhi NR, Mathema B, Mlisana K, <strong>Brust JCM</strong>. High prevalence of inhA promoter mutations among patients with drug-resistant tuberculosis in KwaZulu-Natal, South Africa. PLoS One 2015; 10(9):e0135003. doi: 10.1371/journal.pone.0135003</p>
<p> </p>
<p>Shah NS, Auld S, <strong>Brust JCM</strong>, Mathema B, Ismail N, Moodley P, Mlisana K, Allana S, Campbell A, Mthiyane T, Morris N, Mpangase P, Vally Omar S, Brown T, Narenchania A, Shaskina E, Kapwata T, Kreiswirth B, Gandhi NR. <em>Transmission of Extensively Drug-Resistant Tuberculosis in South Africa</em>. N Engl J Med 2017; 376(3):243-253</p>
<p> </p>
<p><strong>Brust JCM</strong>, Shah NS, Mlisana K, Moodley P, Allana S, Campbell A, Johnson BA, Master I, Mthiyane T, Lachman S, Larkan L-M, Ning Y, Malik A, Smith JP, Gandhi NR. <em>Improved survival and cure rates with concurrent treatment for MDR-TB/HIV co-infection in South Africa.</em> Clin Infect Dis. 2018; 66(8):1246-1253.</p>
<p> </p>
<p>Wasserman S, Denti P, <strong>Brust JCM</strong>, Abdelwahab M, Hlungulu S, Wiesner L, Norman J, Sirgel FA, Warren RM, Esmail A, Dheda K, Gandhi NR, Meintjes G, Maartens G. <em>Linezolid pharmacokinetics in South African patients with drug resistant tuberculosis and a high prevalence of HIV co-infection.</em> Antimicrob Agents Chemother 2019 63(3):e02164-18</p>
<p> </p>
<p>Meintjes G, <strong>Brust JCM</strong>, Nutall J, Maartens G. <em>Management of active tuberculosis in adults with HIV</em>. Lancet HIV 2019; 6: e463–74</p>
<p> </p>
<p>Smith JP, Gandhi NR, Shah NS, Mlisana K, Moodley P, Johnson BA, Allana S, Campbell A, Nelson KN, Master I, <strong>Brust JCM</strong>. <em>The impact of concurrent antiretroviral therapy and MDR-TB treatment on adverse events</em>. J Acquir Immune Defic Syndr 2020; 83(1):47-55</p>
<p> </p>
<p>Ngwalero P*, <strong>Brust JCM*</strong>, van Beek SW, Wasserman S, Maartens G, Meintjes G, Joubert A, Norman J, Castel S, Gandhi NR, Denti P, McIlleron H, Svensson EM, Wiesner L. Relationship between plasma and intracellular concentrations of bedaquiline and its M2 metabolite in South African patients with rifampin-resistant TB. Antmicrob Agents Chemother. 2021; 65(11):e0239920. doi: 10.1128/AAC.02399-20</p>
<p class="MsoListParagraph" style="mso-add-space: auto; text-indent: -.25in; mso-list: l0 level1 lfo1; tab-stops: list 40.5pt; margin: 0in 0in 6.0pt 40.5pt;"> </p>
<p><strong style="text-indent: -0.25in;">Brust JCM</strong><span style="text-indent: -0.25in;">, Gandhi NR, Wasserman S, Maartens G, Omar SV, Ismail NA, Campbell A, Joseph L, Hahn A, Allana S, Hernandez-Romieu AC, Zhang C, Mlisana K, Viljoen CA, Zalta B, Ebrahim I, Franczek M, Master I, Ramangoaela L, Te Riele J, Meintjes G; PROBeX Study Team. </span><em style="text-indent: -0.25in;">Effectiveness and cardiac safety of bedaquiline-based therapy for drug-resistant tuberculosis: a prospective cohort study. </em><span style="text-indent: -0.25in;">Clin Infect Dis. 2021; 73(11):2083-2092</span></p>
<p> </p>
Maneesha D. Bangar
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<p class="Paragraph SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; overflow-wrap: break-word; white-space: pre-wrap; vertical-align: baseline; font-kerning: none; background-color: transparent; color: windowtext;"><span class="TextRun SCXW54015224 BCX0" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-variant-ligatures: none !important; font-size: 11pt; line-height: 19.55px; font-family: Lato, Lato_EmbeddedFont, Lato_MSFontService, sans-serif;" xml:lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">Maneesha Bangar, MD, is Director, Simulation for Education and Patient Safety in Critical Care and Assistant Professor, Medicine at Montefiore Einstein. Her clinical interests include </span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">providing</span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;"> care for complex ICU patients, critical care consults, trainin</span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">g house staff in running Rapid Response and Cardiac Arrest Codes emphasizing communication and teamwork skills, training CCM Fellows in airwa</span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">y</span> <span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">management,</span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;"> emergency procedures, </span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">hands on ultrasound training and </span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">multisystem bedside training to efficiently manage emergencies</span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">. She is also involved</span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;"> in conducting multidisciplinary in situ simulations for better patient care with other departments</span></span><span class="EOP SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-size: 11pt; line-height: 19.55px; font-family: Lato, Lato_EmbeddedFont, Lato_MSFontService, sans-serif;" data-ccp-props="{"134245417":true,"201341983":0,"335559740":276}"> </span></p>
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<p class="Paragraph SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; overflow-wrap: break-word; white-space: pre-wrap; vertical-align: baseline; font-kerning: none; background-color: transparent; color: windowtext;"><span class="TextRun SCXW54015224 BCX0" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-variant-ligatures: none !important; font-size: 11pt; line-height: 19.55px; font-family: Lato, Lato_EmbeddedFont, Lato_MSFontService, sans-serif;" xml:lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">In 1999, Dr. Bangar completed her medical education at B.J. Medical College in Pune, Maharashtra, India. She completed her yearlong rotating internship at </span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">Sassoon General Hospital, Pune, India in 2000 followed by a job as a Medical Officer in rural India. She then completed a three-year anesthesiology </span><span class="NormalTextRun ContextualSpellingAndGrammarErrorV2Themed SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; background-repeat: repeat-x; background-position: left bottom; background-image: var(--urlContextualSpellingAndGrammarErrorV2, ); border-bottom: 1px solid transparent;">residency</span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;"> at B.J. Medical College in 2004. Dr. Bangar later pursued </span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">additional</span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;"> postgraduate training at Mont</span><span class="NormalTextRun SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">efiore, completing an internal medicine residency in 2012, acting as Chief Resident in her final year, followed by a two-year critical care medicine fellowship, which she completed in 2014.</span></span></p>
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<p class="Paragraph SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; overflow-wrap: break-word; white-space: pre-wrap; vertical-align: baseline; font-kerning: none; background-color: transparent; color: windowtext;"><span class="EOP SCXW54015224 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-size: 11pt; line-height: 19.55px; font-family: Lato, Lato_EmbeddedFont, Lato_MSFontService, sans-serif;" data-ccp-props="{"134245417":true,"201341983":0,"335559740":276}"><span class="TextRun SCXW195280366 BCX0" lang="EN-US" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent; font-size: 11pt; line-height: 19.55px; font-variant-ligatures: none !important;" xml:lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW195280366 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">Dr. Bangar is board certified in Internal Medic</span><span class="NormalTextRun SCXW195280366 BCX0" style="margin: 0px; padding: 0px; user-select: text; -webkit-user-drag: none; -webkit-tap-highlight-color: transparent;">ine and Critical Care Medicine. She is a member of the Society of Critical Care Medicine and the American College of Physicians. In 2022, she was awarded Faculty Scholar for the Harvard Macy Program for Educators in Health Professions.</span></span> </span></p>
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Taking care of the complex ICU patients<br />Critical Care consults<br />Managing RRT/CAC's.<br />Train our CCM/Pulm CCM Fellows and house staff in running the RRT's/CAC's efficiently,emphasizing teamwork and communication skills.<br />Conduct airway workshop for our CCM/Pul CCM Fellows<quillbot-extension-portal></quillbot-extension-portal>
Dr. Bangar's involved in research on applications of simulation to increase efficiency in patient management, uncovering latent safety threats and quality improvement.<quillbot-extension-portal></quillbot-extension-portal>
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<p class="MsoNormal"><strong><span style="text-decoration: underline;"><span style="font-size: 11.0pt; font-family: 'Arial Black',sans-serif; mso-bidi-font-family: 'Arial Black';">National Presentations</span></span></strong></p>
<p class="MsoNormal" style="margin-left: 1.25in; text-indent: -1.0in;"><strong><span style="font-size: 11.0pt;"><span style="mso-tab-count: 1;"> </span></span></strong><span style="font-size: 11.0pt;">Ninan, Priyanka; <strong style="mso-bidi-font-weight: normal;">Bangar Maneesha MD</strong>; Yang Christina - Use of <span style="mso-tab-count: 1;"> </span><span style="mso-tab-count: 1;"> </span></span><span style="font-size: 11pt;">in-situ simulation to identify intubation-associated latent safety </span><span style="font-size: 11pt;">threats in critical care units in a COVID-19 epicenter 22nd </span><span style="font-size: 11pt;">International Meeting on Simulation in Healthcare (Presented at </span><span style="font-size: 11pt;">IMSH 2022)</span><span style="font-size: 11pt;"> </span></p>
<p class="MsoNormal" style="margin-left: 1.25in;"><span style="font-size: 11.0pt;">Brooke Hassan, BA<sup>1</sup>; Zachary Kelly, MD<sup>1</sup>; Daniel Li, MD<sup>1</sup>;</span><span style="font-size: 11pt;">Elliot Schiff, BA</span><sup>1</sup><span style="font-size: 11pt;">; Marc- Mina Tawfik, BS</span><sup>1</sup><span style="font-size: 11pt;">; </span><strong style="font-size: 11pt;">Bangar Maneesha MD</strong><span style="font-size: 11pt;">; </span><span style="font-size: 11pt;">Bradley Schiff, MD</span><sup>1,2</sup><span style="font-size: 11pt;">; Christina J. Yang, MD</span><sup>1,2</sup><span style="font-size: 11pt;"> - Identifying Latent S</span><span style="font-size: 11pt;">afety Threats Using an I</span><em style="font-size: 11pt;">n Situ</em><span style="font-size: 11pt;"> Simulation-Based Adult Tracheostomy </span><span style="font-size: 11pt;">Care Quality Improvement Model (Presented at the American Academy </span><span style="font-size: 11pt;">of Otolaryngology-Head and Neck Surgery Annual Meeting Simulation </span><span style="font-size: 11pt;">Showcase, Sept 12, 2022, Philadelphia PA)</span></p>
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<p class="MsoNormal"><strong><span style="font-size: 11.0pt; font-family: 'Arial Black',sans-serif; mso-bidi-font-family: 'Arial Black';">Original Communications in Reviewed Journals: </span></strong></p>
<p class="MsoNormal"><strong><span style="font-size: 11.0pt; font-family: 'Times New Roman',serif; mso-fareast-font-family: 'Times New Roman'; mso-ansi-language: EN-US; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">Manuscripts</span></strong></p>
<p class="MsoNormal"><span style="font-size: 11pt;">Alfredo Lee Chang MD, Andrew Dym MD, Carla Venegas-Borsellino MD, </span><strong style="font-size: 11pt;">Bangar</strong> <strong style="font-size: 11pt;">Maneesha MD</strong><span style="font-size: 11pt;">, Massoud Kazzi MD, Dmitry Lisenenkov MD, Nida Qadir MD, Adam Keene MD, </span><span style="font-size: 11pt;">Lewis Eisen MD.</span><span style="font-size: 11pt;"> “A Comparison of Simulation-Based Training versus Lecture-Based Education in Teaching Situation Awareness – A Randomized Controlled Study”. Annals of the American Thoracic Society. 2017; 14:529-535.</span></p>
<p class="MsoNormal"><span style="font-size: 11pt; color: #222222; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;">Yekaterina Kim MD, Andrew Dym MD, Karen Yang MD, Daniel Fein MD, </span><strong><span style="font-size: 11.0pt;">Bangar</span></strong><span style="font-size: 11.0pt;"> <strong>Maneesha MD</strong><span style="color: #222222; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;">, Hannah Ferenchick MD, Adam Keene MD, Deborah Orsi MD, Moses Washington MD, Lewis Eisen MD. “The Effect of Numbered Jerseys on Directed Commands, Teamwork, and Clinical Performance During Simulated Emergencies”. </span></span><span style="color: #222222; font-size: 11pt;">Journal of Healthcare Quality. 2021; 43:24-31.</span><strong><span style="font-size: 11.0pt; font-family: 'Arial Black',sans-serif; mso-bidi-font-family: 'Arial Black';"> </span></strong></p>
<p class="MsoNormal"><strong><span style="font-size: 11.0pt; font-family: 'Arial Black',sans-serif; mso-bidi-font-family: 'Arial Black';">Books, Book Chapters</span></strong><span style="font-size: 11.0pt; font-family: 'Arial Black',sans-serif; mso-bidi-font-family: 'Arial Black';">, <strong>Review Articles: </strong></span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Venegas-Borsellino C, <strong>Bangar</strong> <strong>Maneesha MD</strong>. CPR and ACLS Updates. In: Oropello J, Pastores S, Kvetan V (editors). Current Diagnosis and Therapy in Critical Care Medicine. McGraw-Hill Medical, USA. 2014.</span><strong><span style="font-size: 11.0pt;"> </span></strong></p>
<p class="MsoNormal"><strong><span style="font-size: 11.0pt;">Bangar</span></strong><span style="font-size: 11pt;"> <strong>Maneesha MD</strong>, Carla Venegas MD, Lewis Eisen MD. “Simulation and Education in the ICU” in Lange Critical Care, Eds. John Oropello MD, Stephen Pastores MD, Vladimir Kvetan MD, Lange; 2016: 962-970.</span><span style="font-size: 11.0pt; font-family: 'Arial Black',sans-serif; mso-bidi-font-family: 'Arial Black';"><strong> </strong></span></p>
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<p class="MsoNormal"><strong><span style="font-size: 11.0pt; font-family: 'Arial Black',sans-serif; mso-bidi-font-family: 'Arial Black';">Abstracts/Presentations:</span></strong><span style="font-size: 11.0pt; font-family: 'Arial Black',sans-serif; mso-bidi-font-family: 'Arial Black';"> </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">W. Marino MD, J. Harigopalan MD, <strong>Bangar Maneesha MD</strong>. A case report on Smoker with Lung Mass . Chest. 2011 Feb:139(2):460-3. Doi:1378/chest.10-1674. </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">T. Aksoy MD ,S. Davuluri MD, <strong>Bangar Maneesha MD</strong>, G. Goel MD, P.Sivaraju PharmD. Minimizing Warfarin Associated Adverse Events in Hospitalized Adults. JAMDA Vol 12,Issue 3, Page B-16,March 2011 </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Carla Venegas-Borsellino MD, <strong>Bangar Maneesha MD</strong>, Matthew Durst, Lewis Eisen MD.-Use of simulation checklist to improve safety during intra-hospital transport of the critically ill. Critical Care Medicine:</span><a href="http://journals.lww.com/ccmjournal/toc/2013/12001"><span style="color: windowtext; text-decoration-line: none;">December 2013</span></a><span style="font-size: 11.0pt;"> doi:10.1097/01.ccm.0000439192.75425.bb </span><span style="font-size: 11.0pt;"> </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Venegas-Borsellino C, Dym A, Madahar P, Mejia E, <strong>Bangar Maneesha MD</strong>, Colvin M, Eisen L. (2014). An evaluation of leadership and teamwork skills by internal medicine residents during in-hospital cardiac arrest and rapid response scenarios after simulation training. </span><a href="http://journal.publications.chestnet.org/article.aspx?articleid=1912910…; target="_blank" rel="noopener"><span style="color: windowtext; text-decoration-line: none;">CHEST. 2014; 146:491A. </span></a></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Dym, Akiva Andrew; Venegas-Borsellino, Carla; <strong>Bangar Maneesha MD</strong>; Lisenenkov, Dmitry; Keene, Adam; Eisen, Lewis. TEACHING SITUATION AWARENESS DURING CARDIAC ARRESTS AND RAPID RESPONSES - A SIMULATION STUDY. Critical Care Medicine: </span><a href="https://journals.lww.com/ccmjournal/toc/2014/12001"><span style="color: windowtext; text-decoration-line: none;">December 2014 - Volume 42 - Issue 12 - p A1372</span></a><span style="font-size: 11.0pt;"> doi: 10.1097/01.ccm.0000457546.56888.20 </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Alfredo Lee Chang MD, Akiva Dym BS, Nida Qadir MD, Carla Venegas-Borsellino MD, <strong>Bangar Maneesha MD</strong>, Dmitry Lisenenkov MD, Lewis Eisen MD “Airway Management Boot Camp for Incoming Critical Care Fellows - A Simulation Study” CHEST. 2015;148:460A. </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Alfredo Lee Chang MD, Akiva Dym BS, Nida Qadir MD, Carla Venegas-Borsellino MD, <strong>Bangar Maneesha MD</strong>, Dmitry Lisenenkov MD, Lewis Eisen MD. “A Comparison of Simulation Training versus Classroom-Based Education in Teaching Situation Awareness – Randomized Control Study” CHEST. 2015;148:461A. </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Akiva Dym BS, Nida Qadir MD, Massoud Khazzi MD, <strong>Bangar Maneesha MD</strong>, Dmitry Lisenenkov MD, Adam Keene MD, Lewis Eisen MD. "Comparison of Objective and Subjective Measurements of Situation Awareness in Simulated Emergencies" Crit Care Med. 2015;43:62-63. </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Akiva Dym BS, <strong>Bangar Maneesha MD</strong>, Adam Keene MD, Dmitry Lisenenkov MD, Lewis Eisen MD. "An Evaluation of Situation Awareness During In-Hospital Cardiac Arrest and Rapid Responses" Crit Care Med. 2015;43:57. </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Alfredo Lee Chang, MD; Akiva Dym, BS; <strong>Bangar Maneesha MD</strong>; Adam Keene, MD; Marjan Rahmanian, MD; Nida Qadir, MD; Lewis Eisen, MD </span><span style="font-size: 11.0pt;">A Comparison of Observed vs Self-Rated Teamwork During Simulated Cardiac Arrest and Rapid Response Scenarios, DOI:https://doi.org/10.1016/j.chest.2016.08.692 </span><span style="font-size: 11.0pt;"> </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Dym, Akiva; Lee Chang, Alfredo; <strong>Bangar Maneesha MD</strong>; Keene, Adam; Rahmanian, Marjan; Qadir, Nida; Eisen, Lewis OBSERVED TEAMWORK CORRELATES WITH CLINICAL PERFORMANCE DURING SIMULATED MEDICAL EMERGENCIES. Critical Care Medicine: <a href="https://journals.lww.com/ccmjournal/toc/2016/12001"><span style="color: windowtext; text-decoration-line: none;">December 2016 - Volume 44 - Issue 12 - p 178</span></a> doi: 10.1097/01.ccm.0000509083.52281.74 </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Kim Y, Orsi D, Keene A, Ferenchick H, <strong>Bangar Maneesha MD</strong>, Fein DG, Dym AA, Eisen L. Numbered Jerseys Improve Teamwork During Simulated Emergencies: A Randomized Controlled Trial. Critical Care Medicine: January 2018 - Volume 46 - Issue 1 - p 179. doi: 10.1097/01.ccm.0000528411.39325.40 </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Marjan Islam, MD, <strong>Bangar Maneesha MD</strong>, Ariel L. Shiloh, MD, A Woman in Her 70s on Anticoagulation With Sudden Shock, CHEST Volume 155 Issue 5 Pages e123-e126 (May 2019) DOI: 10.1016/j.chest.2018.10.052 </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Nathaniel Kratz, MD, Galina Glazman-Kuczaj, Karen Yang, Andrew Dym, Daniel Fein, <strong>Bangar Maneesha MD</strong>, Emily Kaplan, Lewis Eisen </span><span style="font-size: 11.0pt;">PRE-CHARGING THE DEFIBRILLATOR DURING ACLS TO REDUCE INTERRUPTIONS: A RANDOMIZED CONTROLLED SIMULATION STUDY </span><span style="font-size: 11.0pt;">DOI:https://doi.org/10.1016/j.chest.2019.08.1003 </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Yang, Karen; Glazman-Kuczaj, Galina; McPhee, Christa; Kratz, Nathaniel; Dym, Akiva; Kaplan, Emily; Chen, Jen-Ting; <strong>Bangar Maneesha MD</strong>; Eisen, Lewis </span><span style="font-size: 11.0pt;">1501: PRECHARGING THE DEFIBRILLATOR DURING ACLS TO REDUCE INTERRUPTIONS: A RANDOMIZED CONTROLLED STUDY, Critical Care Medicine: January 2020 - Volume 48 - Issue 1 - p 726 </span><span style="font-size: 11.0pt;">doi: 10.1097/01.ccm.0000647912.27681.b3 </span></p>
<p class="MsoNormal"><span style="font-size: 11.0pt;">Luke Andrea, M.D.<a href="https://evidence.nejm.org/doi/full/10.1056/EVIDe2200247#a1"><span style="color: windowtext; text-decoration-line: none;">1</span></a>, <strong>Bangar Maneesha MD</strong>, and Ari Moskowitz, M.D., M.P.H. Q</span><span style="font-size: 11pt;">uestions Remain about Targeted Temperature Management in Cardiac Arrest, NEJM Evid 2022; 1 (11) DOI:</span><a style="font-size: 11pt;" title="DOI" href="https://doi.org/10.1056/EVIDe2200247"><span style="color: windowtext; text-decoration-line: none;">https://doi.org/10.1056/EVIDe2200247</span></a></p>
<p class="MsoNormal"><strong><span lang="DE" style="font-size: 11.0pt; mso-ansi-language: DE;">National/International Presentations:</span></strong></p>
<p class="MsoNormal"><span style="font-size: 14.6667px;"><strong>Bangar Maneesha MD</strong>, Gulati Anita MD, Kalpana Kelkar MD. Anesthetic management in a case of Ebstein’s anomaly .50th </span><span style="font-size: 14.6667px;">National Conference of Indian Society of Anethesiology</span></p>
<p class="MsoNormal"><span style="font-size: 14.6667px;"><strong>Bangar Maneesha MD</strong>, Dr T Dharmarajan. MD. Paranoia, </span><span style="font-size: 14.6667px;">as a presentation of Graves’ disease. Poster at Bronx county </span><span style="font-size: 14.6667px;">medical society</span></p>
<p class="MsoNormal"><span style="font-size: 14.6667px;"><strong>Bangar Maneesha MD</strong>, Dr T Dharmarajan MD. Altered Mental </span><span style="font-size: 14.6667px;">Status: The cause may be in the heart! Poster- Bronx county </span><span style="font-size: 14.6667px;">medical society.</span></p>
<p class="MsoNormal"><span style="font-size: 14.6667px;"><strong>Bangar Maneesha MD</strong>, Venegas-Borsellino C, Colvin M, </span><span style="font-size: 14.6667px;">Dym AA, Shiloh AL, Dudaie R, Eisen L. (2013). Board 304 – </span><span style="font-size: 14.6667px;">Research Abstract Leadership Skills and Clinical Performance </span><span style="font-size: 14.6667px;">of Internal Medicine Residents in Cardiac Arrests and Rapid </span><span style="font-size: 14.6667px;">Responses - A Simulation Study (Submission #504). Simulation </span><span style="font-size: 14.6667px;">in Healthcare, 8(6)</span></p>
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<p>Maneesha Bangar, MD, is Director, Simulation for Education and Patient Safety in Critical Care and Assistant Professor, Medicine at Montefiore Einstein. Her clinical interests include providing care for complex ICU patients, critical care consults, training house staff in running Rapid Response and Cardiac Arrest Codes emphasizing communication and teamwork skills, training CCM Fellows in airway management, emergency procedures, hands on ultrasound training and multisystem bedside training to efficiently manage emergencies. She is also involved in conducting multidisciplinary in situ simulations for better patient care with other departments</p><p>In 1999, Dr. Bangar completed her medical education at B.J. Medical College in Pune, Maharashtra, India. She completed her yearlong rotating internship at Sassoon General Hospital, Pune, India in 2000 followed by a job as a Medical Officer in rural India. She then completed a three-year anesthesiology residency at B.J. Medical College in 2004. Dr. Bangar later pursued additional postgraduate training at Montefiore, completing an internal medicine residency in 2012, acting as Chief Resident in her final year, followed by a two-year critical care medicine fellowship, which she completed in 2014.</p><p>Dr. Bangar’s research includes the applications of simulation to increase efficiency in patient management, uncovering latent safety threats and quality improvement. She has shared her work through peer-reviewed journals, book chapters, abstracts and poster presentations.</p><p>Dr. Bangar is board certified in Internal Medicine and Critical Care Medicine. She is a member of the Society of Critical Care Medicine and the American College of Physicians. In 2022, she was awarded Faculty Scholar for the Harvard Macy Program for Educators in Health Professions.</p>