Mitchell Steinschneider
<p>The goal of my research is to delineate the multiple fields of auditory and auditory-related cortex, identify their functional connectivity, and clarify the roles that each of these regions play in the neural processing of speech and other complex hearing phenomena. The three arms of my research career, coupled to my clinical career arms, make me ideally suited to contribute to this academic endeavor. Pertaining to the first arm, I was among the first investigators to rigorously examine auditory cortical mechanisms of speech processing in an animal model. Previously, it had been thought that animals would make poor models for this uniquely human process. My colleagues and I demonstrated that auditory cortical activity could explain many of features of speech processing, such as the neural events associated with the categorical representation of the voice onset time parameter, in the non-human primate model. This line of research has expanded over the years to address many of the key issues in auditory neuroscience, including clarifying neural mechanisms underlying auditory scene analysis, musical consonance and dissonance, pitch, and the mismatch negativity component of the human auditory evoked potential. We have also been among the first to demonstrate the close correspondence between monkey auditory cortical activity and that recorded directly from the human auditory cortex using intracranial electrodes. While I have retired from this research arm to increase my role on this project and pursue my mandate to help lead the new program of intracranial recordings in children at U Iowa, my animal research background helps ground this project in tenets of basic auditory cortical physiology.</p>
<p>The second arm of my research has been as co-investigator on this long-standing project. Working with the University of Iowa investigative team, I have been a major contributor to their intracranial studies that have helped delineate fundamental features of human auditory cortical physiology. In the last several years, working with Dr. Nourski as co-first author on multiple papers, we have identified the relative modulations of core and non-core auditory cortex by attention, and the role of these fields and auditory-related cortex including the middle temporal gyrus, supramarginal gyrus, and prefrontal cortex in word object formation and selection and in predictive coding mechanisms.</p>
<p>The third arm of my research, in collaboration with Dr. Elyse Sussman, and more recently, Dr. Monica Wagner, has focused on clarifying the maturation of cortical auditory evoked potentials and the effects of language experience on cortical speech processing. Finally, my 30 years of clinical experience in child neurology and clinical electrophysiology has made me keenly aware of multiple types of developmental language disorders and normal and aberrant features of the electroencephalogram. These experiences allow me to frame research questions in a translationally relevant way.</p>
<p><strong>Steinschneider, M.</strong>, & Fishman, Y.I. (2011). Enhanced physiologic discriminability of stop consonants with prolonged formant transitions in awake monkeys based on the tonotopic organization of primary auditory cortex. Hearing Research, 271, 103-114. PMCID: PMC2945626</p>
<p><strong>Steinschneider, M.</strong>, Nourski, K., Kawasaki, H., Oya, H., Brugge, J.F., & Howard, M.A. III. (2011). Intracranial study of speech-elicited activity on the human posterolateral superior temporal gyrus. Cerebral Cortex, 21, 2332-2347. PMCID: PMC3169661</p>
<p><strong>Steinschneider, M.</strong>, Nourski, K.V., & Fishman, Y.I. (2013). Representation of speech in human auditory cortex: Is it special? Hearing Research, 305, 57-73. Invited Paper for Special Issue: Communication Sounds and the Brain: New Directions and Perspectives. PMCID: PMC3818517.</p>
<p>Fishman, Y.I., Micheyl, C., & <strong>Steinschneider, M.</strong> (2012). Neural mechanisms of rhythmic masking release in monkey primary auditory cortex: Implications for models of auditory scene analysis. Journal of Neurophysiology, 107, 2366-2382. PMCID: PMC3362241</p>
<p>Fishman, Y.I., Micheyl, C., & <strong>Steinschneider, M.</strong> (2014). Neural representation of concurrent harmonic sounds in monkey primary auditory cortex: Implications for models of auditory scene analysis. Journal of Neuroscience, 34, 12425-12443. PMICD: PMC4160777.</p>
<p>Fishman, Y.I., Kim, M., <strong>Steinschneider, M.</strong> (2017). A Crucial Test of the Population Separation Model of Auditory Stream Segregation in Macaque Primary Auditory Cortex. Journal of Neuroscience, 37 10645-10655. PMID: 28954867.</p>
<p>Nourski, K.V., <strong>Steinschneider, M.</strong>, Rhone, A.E. Electrocorticographic activation within human auditory cortex during dialog-based language and cognitive testing. Frontiers in Human Neuroscience (2016) May 4;10:20. PMID: 27199720. K.V.N. and M.S. contributed equally to this work.</p>
<p>Nourski, K.V., <strong>Steinschneider, M.</strong>, Rhone, A.E., Howard, M.A. Intracranial electrophysiology of auditory selective attention associated with speech classification tasks. Frontiers in Human Neuroscience (2017) Jan 10:691. doi:10.3389/fnhum.2016.00691 K.V.N. and M.S. contributed equally to this work.</p>
<p>Nourski, K.V., <strong>Steinschneider, M.</strong>, Rhone, A.E., Kawasaki, H., Todd, M.M., Howard, M.A., Banks, M.I. Processing of auditory novelty across the cortical hierarchy: An intracranial electrophysiology study. NeuroImage 183 (2018) 412-424. PMID: 30114466.</p>
<p>Sussman, E., <strong>Steinschneider, M.</strong>, Gumenyuk, V., Grushko, J., & Lawson, K. (2008). The maturation of human evoked brain potentials to sounds presented at different stimulus rates. Hearing Research, 236, 61-79. PMCID: PMC2567844</p>
Shlomo Shinnar
<p>Dr. Shlomo Shinnar is a neurologist, pediatrician and epidemiologist. His expertise focuses on comprehensive epilepsy management, child neurology and epilepsy with a focus on long term studies the prognosis of childhood seizures disorders. He is also an experienced clinical trialist and is the co-director of the Einstein NeuroNEXT cener of Excellence for Clinical Trials in Neurology.<br /><br />Dr. Shinnar conducts research on a variety of topics relating to childhood seizures, including when to initiate and discontinue antiepileptic drug therapy, prognosis following a first seizure, and prognosis following discontinuation of medications in children with seizures. He is also interested in the comorbidities of epilepsy and its impact on chilren and families. He current studies focus on status epilepticus, a life-threatening condition of persistent continuous and unremitting brain seizure lasting longer than 30 minutes. He is also involved in research in autism, an increasingly common neurological condition in childhood.<br /><br />His current research focuses on the consequences of prolonged febrile seizures, the most common seizure seen in children and on the long term outcomes of childhood absence (petit-mal) seizures which are the most common form of epilepsy in children. He is also on the executive commitee of the recentlyfunded ESETT (Established Status Epilepticus Treatment Trial) trial which seeks to determine the optimal therapy for convulsive status epilepticus inchildren and adults when first line therapy with a benzodiazepine has failed.</p>
<p>Dr. Shinnar is the senior editor of the book <em>Childhood Seizures</em> and co-editor of the book <em>Febrile Seizures</em>. He has published over 185 original papers and over 125 reviews and chapters. He is the recipient of the prestigious Research Recognition Award of the American Epilepsy Society and the CURE research award. His continuing research on the Consequences of Prolonged Febrile Seizures in Children (FEBSTAT) study was recently recognized with the prestigious Javits award by the NINDS.<br /><br /></p>
<p>Most recent publications:</p>
<p>ORIGINAL PAPERS:</p>
<p>Sillanpaa M, Shinnar S. SUDEP and other causes of mortality in childhood-onset epilepsy<span style="text-decoration: underline;">. Epilepsy & Behavior</span> 2013;28:249-255. PMID: 23746924</p>
<p> Hesdorffer DC, Shinnar S, Lewis DV, Nordli DR Jr, Pellock JM, Moshe SL, Shinnar RC, Litherand C, Bagiella E, Frank LM, BelloJA, Chan S, Masur D, Macfall J, Sun S and the Consequences of Prolonged Febrile Seizures (FEBSTAT) Study Team. Risk Factors for Febrile Status Epilepticus: A case control study. <span style="text-decoration: underline;">J Pediatr</span> 2013; 163:1147-1151. PMID: 23809042 PMCID: PMC3989363</p>
<p> Masur D, Shinnar S, Cnaan A, Shinnar RC, Clark P, Wang J, Weiss EF, Hirtz DG, Glauser TA, Childhood Absence Epilepsy Study Group. Pretreatment cognitive deficits and treatment effects on attention in childhood absence epilepsy. <span style="text-decoration: underline;">Neurology</span> 2013; 81:1572-1580. PMID: 24089388. PMCID: PMC3980500</p>
<p> Brown FC, Westerveld M, Langfitt JT, Hamberger M, Hamid H, Shinnar S, Sperling MR, Devinsky O, Barr W, Tracy J, Masur M, Bazil CW, Spencer SS. Influence of anxiety on memory performance in temporal lobe epilepsy. <span style="text-decoration: underline;">Epilepsy & Behavior</span> 2014; 31:19-24. PMID: 24291525 PMCID: PMC3946774.</p>
<p> Lewis DV, Shinnar S, Hesdorffer DC, Bagiella E, Bello JA, Chan S, Xu Y, MacFall J, Gomes WA, Moshe SL, Mathern GW, Pellock JM, Nordli DR Jr, Frank LM, Provenzale J, Shinnar RC, Epstein LG, Masur D, Litherand C, Sun S; FEBSTAT Study Team. Hippocampal sclerosis after febrile status epilepticus: The FEBSTAT study<span style="text-decoration: underline;">. Ann Neurol</span> 2014;75:178-185. PMID# 24318290 NIHMSID# 569823 PMCID: PMC3980500</p>
<p> Hussain SA, Shinnar S, Kwong G, Lerner JT, Matsumoto JH, Wu JY, Sields WD, Sankar R. Treatment of infantile spasms with very high dose prednisolone before high dose adrenocorticotropic hormone. Epilepsia 2014;55:103-107. PMID 24446954 OMCID: PMC3904676</p>
<p> Hamid H, Blackmon K, Cong X, Dziura J, Atlas LY, Vickrey BG, Berg AT, Bazil CW, Langfitt JT, Walczak TS, Sperling MR, Shinnar S, Devinsky O. Mood anxiety and incomplete seizure control affect quality of life after epilepsy surgery. <span style="text-decoration: underline;">Neurology</span> 2014; 82:887-894. PMID 24489129 PMCID: PMC3959755.</p>
<p> Seinfeld S, Shinnar S, Sun S, Hesdorffer DC, Deng X, Shinnar RC, O’Hara K, Nordli DR Jr, Frank LM, Gallentine W, Moshe SL, Pellock JM and FEBSTAT Study Team. Emergency management of febrile status epilepticus: results of the FEBSTAT study<span style="text-decoration: underline;">. Epilepsia</span> 2014; 55:388-395. PMID 24502379 PMCID: PMC3937844.</p>
<p> Mendley SR, Matheson MB, Shinnar S, Lande MB, Gerson AC, Butler RW, Warady BA, Furth SL, Hooper SR. Duration of chronic kidney disease reduces attention and executive function in pediatric patients. <span style="text-decoration: underline;">Kidney Int</span> 2014; 87:800-806.] PMID 25252026</p>
<p> Valicenti-McDermott M, Lawson K, Hottinger K, Seijo R, Schechtman M, Shulman L, Shinnar S. Parental Stress in Families of Children with Autism and Other Developmental Disabilities. <span style="text-decoration: underline;">J Child Neurol</span> 2015 April 10 [epub ahead of print). PMID: 25862740.</p>
<p> Krumholz A, Wiebe S, Groseth GS, Gloss DS, Sanchez AM, Kabir AA, Liferidge AT, Martello JP, Kanner AM, Shinnar S, Hopp JL, French JA. Evidence-based guideline: Management of an unprovoked first seizure in adults: report of the Guideline Development Subcommittee of the American Academy of Neurology and the American Epilepsy Society. <span style="text-decoration: underline;">Neurology</span> 2015;84:1805-1713. PMIDL 25901057</p>
<p>RECENT REVIEWS:</p>
<p> Gomes WA, Shinnar S. Prospects for imaging-related biomarkers of human epileptogenesis: A critical review. <span style="text-decoration: underline;">Biomark Med</span> 2011;5:599-606. PMID:22003908. PMCID: 3235417.</p>
<p> Shinnar S. Prognostic factors for recurrence after a first unprovoked seizure in childhood. In Arts WF, Arzimanoglou A, Brouwer OF, Camfield C, Camfield P eds. <span style="text-decoration: underline;">Outcome of Childhood Epilepsies.</span> Progress in Epileptic Disorders 2013;12:25-31.</p>
<p> Bleck T, Cock H, Chamberlain J Cloyd J, Connor J, Elm J, Fountain N, Jones E, Lowenstein D, Shinnar S, Silbergleit R, Treiman D, Trinka E, Kapur J. The established status epilepticus trial 2013. <span style="text-decoration: underline;">Epilepsia</span> 2013 54 (suppl 6): 89-92. PMID 24001084 PMCID: PMC4048827</p>
<p> Patterson KP, Baram TZ, Shinnar S. Origins of Temporal Lobe Epilepsy: Febrile seizures and Febrile Status Epilepticus. <span style="text-decoration: underline;">Neurotherapeutics</span> 2014; 11:242-250. PMID: 24604424 PMCID: PMC3996115</p>
Ariel L. Shiloh
<p class="MsoNormal" style="background: white;">Dr. Shiloh is the Director of the Critical Care Medicine Consult Service and Professor of Medicine at Montefiore Medical Center/Albert Einstein College of Medicine. As a clinician-educator he serves as the director of critical care ultrasonography. </p>
<p class="MsoNormal" style="background: white;">After receiving his medical degree from the Medical School for International Health at Ben Gurion University of the Negev in 2005, he completed both his Internal Medicine residency and Critical Care Medicine fellowship at Montefiore Medical Center/Albert Einstein College of Medicine. Dr. Shiloh joined the Montefiore/Einstein Critical Care faculty in 2010. </p>
<p class="MsoNormal" style="background: white;"> Dr. Shiloh is board-certified in: </p>
<p class="MsoNormal" style="background: white;">· Internal Medicine</p>
<p class="MsoNormal" style="background: white;">· Critical Care Medicine</p>
<p class="MsoNormal" style="background: white;">· Neurocritical Care</p>
<p class="MsoNormal" style="background: white;">· Hospice and Palliative Medicine</p>
<p class="MsoNormal" style="background: white;">As an active member of CHEST, Dr. Shiloh serves as faculty leader and co-chair for the Critical Care Ultrasound: Integration Into Clinical Practice course. He is an active contributor to CHEST’s “Better with Ultrasound” and “Ultrasound Corner” series and a recipient of the “Distinguished Chest Educator” award. <span style="color: #262626; font-family: Verdana;">Award recipients represent the top 4% of CHEST’s international faculty and are recognized for their achievements and long-term contributions to the design and delivery of CHEST education.</span></p>
<p class="MsoNormal" style="background: white;">Dr. Shiloh has authored over 50 original articles, co-edited the “The 5-Minute ICU Consult” published by Lippincott Williams & Wilkins, and has authored over 15 book chapters. His areas of interest and research include use of point of care ultrasonography, early identification of critical illness, and critical care education and simulation training. </p>
<p class="MsoNormal" style="background: white;"> </p>
<p class="MsoNormal" style="background: white;"> </p>
<p class="MsoNormal" style="background: white;"> </p>
Early Detection and Treatment of Critical Illness, Point Of Care Ultrasonography For The Evaluation Of Critical Illness, Advanced Airway Management
Dr. Shiloh's research includes the clinical use of point-of-care ultrasonography in critical illness, improvement of airway management, and cardiopulmonary resuscitation.
<p>1: Shah TE, Vij R, Kim YH, Shiloh AL. Sudden Unilateral Vision Loss in a Patient</p>
<p>Who Received Intravenous Thrombolytic Therapy. Chest. 2021 Dec;160(6):e669-e672.</p>
<p>doi: 10.1016/j.chest.2021.03.074. PMID: 34872684.</p>
<p> </p>
<p>2: Nauka PC, Chen JT, Shiloh AL, Eisen LA, Fein DG. Practice, Outcomes, and</p>
<p>Complications of Emergent Endotracheal Intubation by Critical Care Practitioners</p>
<p>During the COVID-19 Pandemic. Chest. 2021 Dec;160(6):2112-2122. doi:</p>
<p>10.1016/j.chest.2021.06.008. Epub 2021 Jun 15. PMID: 34139207; PMCID:</p>
<p>PMC8204844.</p>
<p> </p>
<p>3: Savel RH, Shiloh AL, Kupfer Y, Hope AA. The Complex Issue of Race and</p>
<p>Coronavirus Disease 2019 in the ICU. Crit Care Med. 2021 Mar 1;49(3):532-535.</p>
<p>doi: 10.1097/CCM.0000000000004766. PMID: 33616353.</p>
<p> </p>
<p>4: Jabbour E, Malik D, Shiloh AL. Sudden Cardiopulmonary Collapse in a Patient</p>
<p>With Coronavirus Disease 2019. Chest. 2021 Feb;159(2):e127-e129. doi:</p>
<p>10.1016/j.chest.2020.05.618. PMID: 33563455; PMCID: PMC7859694.</p>
<p> </p>
<p>5: Savel RH, Kupfer Y, Shiloh AL. Steady As She Goes: Practicing Evidence-Based</p>
<p>Critical Care When the Evidence Is Limited. Chest. 2021 Jan;159(1):7-8. doi:</p>
<p>10.1016/j.chest.2020.09.245. PMID: 33422231; PMCID: PMC7787062.</p>
<p> </p>
<p>6: Tirumandas M, Gendlina I, Figueredo J, Shiloh A, Trachuk P, Jain R, Corpuz M,</p>
<p>Spund B, Maity A, Shmunko D, Garcia M, Barthelemy D, Weston G, Madaline T.</p>
<p>Analysis of catheter utilization, central line associated bloodstream</p>
<p>infections, and costs associated with an inpatient critical care-driven vascular</p>
<p>access model. Am J Infect Control. 2021 May;49(5):582-585. doi:</p>
<p>10.1016/j.ajic.2020.10.006. Epub 2020 Oct 17. PMID: 33080360.</p>
<p> </p>
<p>7: Fein DG, Zhao D, Swartz K, Nauka P, Andrea L, Aboodi M, Shiloh AL, Eisen LA.</p>
<p>The Impact of Nighttime on First Pass Success During the Emergent Endotracheal</p>
<p>Intubation of Critically Ill Patients. J Intensive Care Med. 2021</p>
<p>Dec;36(12):1498-1506. doi: 10.1177/0885066620965166. Epub 2020 Oct 15. PMID:</p>
<p>33054483.</p>
<p> </p>
<p>8: Kapoor S, Chand S, Dieiev V, Fazzari M, Tanner T, Lewandowski DC, Nalla A,</p>
<p>Abdulfattah O, Aboodi MS, Shiloh AL, Gong MN. Thromboembolic Events and Role of</p>
<p>Point of Care Ultrasound in Hospitalized Covid-19 Patients Needing Intensive</p>
<p>Care Unit Admission. J Intensive Care Med. 2021 Dec;36(12):1483-1490. doi:</p>
<p>10.1177/0885066620964392. Epub 2020 Oct 6. PMID: 33021131; PMCID: PMC7539230.</p>
<p> </p>
<p>9: Emami N, Tanner T, Ogundipe F, Hawn VS, Rubin R, Skae CC, Shiloh AL, Keene</p>
<p>AB. Drape to prevent disease transmission during endotracheal intubation. Am J</p>
<p>Infect Control. 2021 Mar;49(3):387-388. doi: 10.1016/j.ajic.2020.06.212. Epub</p>
<p>2020 Jul 3. PMID: 32628982; PMCID: PMC7333628.</p>
<p> </p>
<p>10: Millington SJ, Colvin MO, Shiloh AL, Koenig S. How I Do It: Ultrasound-</p>
<p>Guided Internal Jugular and Femoral Central Venous Catheter Insertion. Chest.</p>
<p>2020 Dec;158(6):2425-2430. doi: 10.1016/j.chest.2020.06.026. Epub 2020 Jun 26.</p>
<p>PMID: 32599065.</p>
<p> </p>
<p>11: Savel RH, Shiloh AL, Saunders PC, Kupfer Y. Mechanical Ventilation During</p>
<p>the Coronavirus Disease 2019 Pandemic: Combating the Tsunami of Misinformation</p>
<p>From Mainstream and Social Media. Crit Care Med. 2020 Sep;48(9):1398-1400. doi:</p>
<p>10.1097/CCM.0000000000004462. PMID: 32496274; PMCID: PMC7302097.</p>
<p> </p>
<p>12: Shiloh AL, McPhee C, Eisen L, Koenig S, Millington SJ. Better With</p>
<p>Ultrasound: Detection of DVT. Chest. 2020 Sep;158(3):1122-1127. doi:</p>
<p>10.1016/j.chest.2020.01.038. Epub 2020 Feb 20. PMID: 32087215.</p>
<p> </p>
<p>13: Islam M, Levitus M, Eisen L, Shiloh AL, Fein D. Lung Ultrasound for the</p>
<p>Diagnosis and Management of Acute Respiratory Failure. Lung. 2020</p>
<p>Feb;198(1):1-11. doi: 10.1007/s00408-019-00309-1. Epub 2020 Jan 1. PMID:</p>
<p>31894411.</p>
<p> </p>
<p>14: Fein DG, Mastroianni F, Murphy CG, Aboodi M, Malik R, Emami N, Abramowitz M,</p>
<p>Shiloh AL, Eisen L. Impact of a Critical Care Specialist Intervention on First</p>
<p>Pass Success for Emergency Airway Management Outside the ICU. J Intensive Care</p>
<p>Med. 2021 Jan;36(1):80-88. doi: 10.1177/0885066619886816. Epub 2019 Nov 10.</p>
<p>PMID: 31707906.</p>
<p> </p>
<p>15: Millington SJ, Hendin A, Shiloh AL, Koenig S. Better With Ultrasound:</p>
<p>Peripheral Intravenous Catheter Insertion. Chest. 2020 Feb;157(2):369-375. doi:</p>
<p>10.1016/j.chest.2019.04.139. Epub 2019 Oct 22. PMID: 31654617.</p>
<p> </p>
<p>16: Wang A, Hendin A, Millington SJ, Koenig S, Eisen LA, Shiloh AL. Better With</p>
<p>Ultrasound: Arterial Line Placement. Chest. 2020 Mar;157(3):574-579. doi:</p>
<p>10.1016/j.chest.2019.08.2209. Epub 2019 Oct 18. PMID: 31634448.</p>
<p> </p>
<p>17: Savel RH, Shiloh AL, Simon RJ, Kupfer Y. Getting It Right for Our Patients:</p>
<p>The Importance of Collaborative Leadership in the ICU. Crit Care Med. 2019</p>
<p>Sep;47(9):1279-1281. doi: 10.1097/CCM.0000000000003880. PMID: 31415316.</p>
<p> </p>
<p>18: Islam M, Bangar M, Shiloh AL. A Woman in Her 70s on Anticoagulation With</p>
<p>Sudden Shock. Chest. 2019 May;155(5):e123-e126. doi:</p>
<p>10.1016/j.chest.2018.10.052. PMID: 31060707.</p>
<p> </p>
<p>19: Patrawalla P, Narasimhan M, Eisen L, Shiloh AL, Koenig S, Mayo P. A</p>
<p>Regional, Cost-Effective, Collaborative Model for Critical Care Fellows'</p>
<p>Ultrasonography Education. J Intensive Care Med. 2020 Dec;35(12):1447-1452. doi:</p>
<p>10.1177/0885066619828951. Epub 2019 Feb 12. PMID: 30755062.</p>
<p> </p>
<p>20: Shiloh AL. Smooth Transitions in Critical Care. J Emerg Trauma Shock. 2018</p>
<p>Jul-Sep;11(3):154-155. doi: 10.4103/JETS.JETS_44_17. PMID: 30429619; PMCID:</p>
<p>PMC6182967.</p>
<p> </p>
<p>21: Savel RH, Shiloh AL. Are We Really Doing More With Less: The Value of Half-</p>
<p>Dose Alteplase in Pulmonary Embolism Therapy. Crit Care Med. 2018</p>
<p>Oct;46(10):1696-1697. doi: 10.1097/CCM.0000000000003303. PMID: 30216306.</p>
<p> </p>
<p>22: Savel RH, Borgia D, Shiloh AL. A Path to High-Quality Care: Implementing</p>
<p>Flexible Visitation While Avoiding Staff Burnout. Crit Care Med. 2018</p>
<p>Jul;46(7):1203-1204. doi: 10.1097/CCM.0000000000003167. PMID: 29912108.</p>
<p> </p>
<p>23: Ferenchick HR, Chua AT, Carlese AJ, Shiloh AL. A Woman With Recent Stroke</p>
<p>Presenting With Respiratory Failure and Shock. Chest. 2018 May;153(5):e101-e103.</p>
<p>doi: 10.1016/j.chest.2017.11.048. PMID: 29731049.</p>
<p> </p>
<p>24: Savel RH, Shiloh AL, Simon RJ, Kupfer Y. Using Big Data to See the Big</p>
<p>Picture in Sepsis. Crit Care Med. 2018 Apr;46(4):640-641. doi:</p>
<p>10.1097/CCM.0000000000002976. PMID: 29538113.</p>
<p> </p>
<p>25: Kumarasamy N, Tishbi N, Mukundan S, Shiloh A, Levsky JM, Haramati LB.</p>
<p>Cardiothoracic MRI in the ICU: A 10-Year Experience. Acad Radiol. 2018</p>
<p>Mar;25(3):359-364. doi: 10.1016/j.acra.2017.09.017. Epub 2018 Feb 6. PMID:</p>
<p>29426683.</p>
<p> </p>
<p>26: Lishmanov A, Bellamkonda TT, Shiloh AL. A Woman in Her 20s With</p>
<p>Cardiopulmonary Failure. Chest. 2017 Jun;151(6):e123-e125. doi:</p>
<p>10.1016/j.chest.2017.01.040. PMID: 28599944.</p>
<p> </p>
<p>27: Shiloh AL, Sobolev M, Di Biase L, Slovut DP. A call for safety during</p>
<p>electrophysiological procedures: US in, why not US out? Authors' reply.</p>
<p>Europace. 2017 Dec 1;19(12):2048-2049. doi: 10.1093/europace/eux007. PMID:</p>
<p>28340047.</p>
<p> </p>
<p>28: Sobolev M, Shiloh AL, Di Biase L, Slovut DP. Ultrasound-guided cannulation</p>
<p>of the femoral vein in electrophysiological procedures: a systematic review and</p>
<p>meta-analysis. Europace. 2017 May 1;19(5):850-855. doi: 10.1093/europace/euw113.</p>
<p>PMID: 27207813.</p>
<p> </p>
<p>29: Shiloh AL, Lominadze G, Gong MN, Savel RH. Early Warning/Track-and-Trigger</p>
<p>Systems to Detect Deterioration and Improve Outcomes in Hospitalized Patients.</p>
<p>Semin Respir Crit Care Med. 2016 Feb;37(1):88-95. doi: 10.1055/s-0035-1570352.</p>
<p>Epub 2016 Jan 28. PMID: 26820276.</p>
<p> </p>
<p>30: Patrawalla P, Eisen LA, Shiloh A, Shah BJ, Savenkov O, Wise W, Evans L, Mayo</p>
<p>P, Szyld D. Development and Validation of an Assessment Tool for Competency in</p>
<p>Critical Care Ultrasound. J Grad Med Educ. 2015 Dec;7(4):567-73. doi:</p>
<p>10.4300/JGME-D-14-00613.1. PMID: 26692968; PMCID: PMC4675413.</p>
<p> </p>
<p>31: Hena KM, Eisen LA, Shiloh AL. A Man in His 60s With Renal Failure and Shock</p>
<p>Refractory to Vasopressors. Chest. 2015 Dec;148(6):e171-e174. doi:</p>
<p>10.1378/chest.15-0160. PMID: 26621295.</p>
<p> </p>
<p>32: Bernier-Jean A, Albert M, Shiloh AL, Eisen LA, Williamson D, Beaulieu Y. The</p>
<p>Diagnostic and Therapeutic Impact of Point-of-Care Ultrasonography in the</p>
<p>Intensive Care Unit. J Intensive Care Med. 2017 Mar;32(3):197-203. doi:</p>
<p>10.1177/0885066615606682. Epub 2016 Jul 9. PMID: 26423745.</p>
<p> </p>
<p>33: Shiloh AL, Adrish M. A Man in His 60s With Cirrhosis, Encephalopathy, and</p>
<p>Shock. Chest. 2015 Jul;148(1):e5-e7. doi: 10.1378/chest.14-2201. PMID: 26149567.</p>
<p> </p>
<p>34: Sobolev M, Slovut DP, Lee Chang A, Shiloh AL, Eisen LA. Ultrasound-Guided</p>
<p>Catheterization of the Femoral Artery: A Systematic Review and Meta-Analysis of</p>
<p>Randomized Controlled Trials. J Invasive Cardiol. 2015 Jul;27(7):318-23. PMID:</p>
<p>26136279.</p>
<p> </p>
<p>35: Adrish M, Shiloh AL. A woman in her 50s with recent coronary artery bypass</p>
<p>grafting presenting with right-sided chest pain. Chest. 2015</p>
<p>May;147(5):e171-e174. doi: 10.1378/chest.14-0457. PMID: 25940259.</p>
<p> </p>
<p>36: Shiloh AL, Ari Eisen L, Savel RH. The unplanned intensive care unit</p>
<p>admission. J Crit Care. 2015 Apr;30(2):419-20. doi: 10.1016/j.jcrc.2014.12.010.</p>
<p>Epub 2014 Dec 24. PMID: 25579373.</p>
<p> </p>
<p>37: Eisen LA, Savel RH, Shiloh AL. Video laryngoscopy in the intensive care</p>
<p>unit. A clearer view? Ann Am Thorac Soc. 2014 Oct;11(8):1254-5. doi:</p>
<p>10.1513/AnnalsATS.201408-386ED. PMID: 25343195.</p>
<p> </p>
<p>38: Chung M, Shiloh AL, Carlese A. Monitoring of the adult patient on</p>
<p>venoarterial extracorporeal membrane oxygenation. ScientificWorldJournal.</p>
<p>2014;2014:393258. doi: 10.1155/2014/393258. Epub 2014 Apr 3. PMID: 24977195;</p>
<p>PMCID: PMC3998007.</p>
<p> </p>
<p>39: Karakitsos D, El Barbary M, Gillman LM, Papalois A, Shiloh A. Critical care</p>
<p>and perioperative monitoring. ScientificWorldJournal. 2014;2014:737628. doi:</p>
<p>10.1155/2014/737628. Epub 2014 May 4. PMID: 24892082; PMCID: PMC4032705.</p>
<p> </p>
<p>40: Tischenkel BR, Gong MN, Shiloh AL, Pittignano VC, Keschner YG, Glueck JA,</p>
<p>Cohen HW, Eisen LA. Daytime Versus Nighttime Extubations: A Comparison of</p>
<p>Reintubation, Length of Stay, and Mortality. J Intensive Care Med. 2016</p>
<p>Feb;31(2):118-26. doi: 10.1177/0885066614531392. Epub 2014 Apr 24. PMID:</p>
<p>24763118.</p>
<p> </p>
<p>41: Shiloh AL, Kazzi MG, Mathew R, Eisen LA, Carlese AJ. A man in his 40s with a</p>
<p>history of hypertension and alcohol dependency presenting to the ED with</p>
<p>respiratory distress: septic shock in the setting of ARDS. Chest. 2014</p>
<p>Feb;145(2):e3-e6. doi: 10.1378/chest.13-2089. PMID: 24493554.</p>
<p> </p>
<p>42: Shiloh AL, Sobolev M, Eisen LA. A woman in her 30s in respiratory distress</p>
<p>with a history of gestational diabetes and hypertension. Chest. 2014</p>
<p>Jan;145(1):e1-e2. doi: 10.1378/chest.13-1850. PMID: 24394849.</p>
<p> </p>
<p>43: Lahiri S, Boro AD, Shiloh AL, Milstein MJ, Savel RH. Periodic Epileptiform</p>
<p>Discharges Clarified for the Nonneurologist Intensivist: Clinical Implications</p>
<p>and Current Management. J Intensive Care Med. 2015 Oct;30(7):385-91. doi:</p>
<p>10.1177/0885066613513411. Epub 2013 Dec 9. PMID: 24323590.</p>
<p> </p>
<p>44: Eisen LA, Janowski W, Shiloh AL. Ultrasound diagnosis of shock in a woman</p>
<p>with metastatic renal cell carcinoma. Chest. 2013 Sep;144(3):e1-e3. doi:</p>
<p>10.1378/chest.13-0964. PMID: 24008972.</p>
<p> </p>
<p>45: Savel RH, Shiloh AL, Eisen LA. Tackling the tough questions: what was this</p>
<p>patient like before they were critically ill? Crit Care Med. 2013</p>
<p>Jan;41(1):327-8. doi: 10.1097/CCM.0b013e318267a8ad. PMID: 23269133.</p>
<p> </p>
<p>46: Shiloh AL, Eisen LA, Yee M, Langner JB, LeDonne J, Karakitsos D. Ultrasound-</p>
<p>guided subclavian and axillary vein cannulation via an infraclavicular approach:</p>
<p>In the tradition of Robert Aubaniac. Crit Care Med. 2012 Oct;40(10):2922-3. doi:</p>
<p>10.1097/CCM.0b013e31825cea64. PMID: 22986669.</p>
<p> </p>
<p>47: Keene AB, Shiloh AL, Dudaie R, Eisen LA, Savel RH. Online testing from</p>
<p>Google Docs™ to enhance teaching of core topics in critical care: a pilot study.</p>
<p>Med Teach. 2012;34(12):1075-7. doi: 10.3109/0142159X.2012.716553. Epub 2012 Aug</p>
<p>30. PMID: 22931149.</p>
<p> </p>
<p>48: Stefanidis K, Pentilas N, Dimopoulos S, Nanas S, Savel RH, Shiloh AL,</p>
<p>Poularas J, Slama M, Karakitsos D. Echogenic Technology Improves Cannula</p>
<p>Visibility during Ultrasound-Guided Internal Jugular Vein Catheterization via a</p>
<p>Transverse Approach. Crit Care Res Pract. 2012;2012:306182. doi:</p>
<p>10.1155/2012/306182. Epub 2012 May 10. PMID: 22649715; PMCID: PMC3357505.</p>
<p> </p>
<p>49: Stefanidis K, Fragou M, Pentilas N, Kouraklis G, Nanas S, Savel RH, Shiloh</p>
<p>AL, Slama M, Karakitsos D. Optimization of Cannula Visibility during Ultrasound-</p>
<p>Guided Subclavian Vein Catheterization, via a Longitudinal Approach, by</p>
<p>Implementing Echogenic Technology. Crit Care Res Pract. 2012;2012:617149. doi:</p>
<p>10.1155/2012/617149. Epub 2012 Apr 23. PMID: 22593825; PMCID: PMC3347863.</p>
<p> </p>
<p>50: Savel RH, Shiloh AL, Eisen LA. Educational impact of continuous chest</p>
<p>compression cardiopulmonary resuscitation: the confidence to "pay it forward"*.</p>
<p>Crit Care Med. 2012 Mar;40(3):992-3. doi: 10.1097/CCM.0b013e31823878b1. PMID:</p>
<p>22343848.</p>
<p> </p>
<p>51: Shiloh AL, Eisen LA, Savel RH. Goal-directed ultrasonography in the</p>
<p>intensive care unit: no more excuses! Crit Care Med. 2011 Apr;39(4):879-80. doi:</p>
<p>10.1097/CCM.0b013e318208e393. PMID: 21613832.</p>
<p> </p>
<p>52: Rosenberg JB, Shiloh AL, Savel RH, Eisen LA. Non-invasive methods of</p>
<p>estimating intracranial pressure. Neurocrit Care. 2011 Dec;15(3):599-608. doi:</p>
<p>10.1007/s12028-011-9545-4. PMID: 21519957.</p>
<p> </p>
<p>53: Kory PD, Pellecchia CM, Shiloh AL, Mayo PH, DiBello C, Koenig S. Accuracy of</p>
<p>ultrasonography performed by critical care physicians for the diagnosis of DVT.</p>
<p>Chest. 2011 Mar;139(3):538-542. doi: 10.1378/chest.10-1479. Epub 2010 Oct 28.</p>
<p>PMID: 21030490.</p>
<p> </p>
<p>54: Shiloh AL, Savel RH, Paulin LM, Eisen LA. Ultrasound-guided catheterization</p>
<p>of the radial artery: a systematic review and meta-analysis of randomized</p>
<p>controlled trials. Chest. 2011 Mar;139(3):524-529. doi: 10.1378/chest.10-0919.</p>
<p>Epub 2010 Aug 19. PMID: 20724734.</p>
<p> </p>
<p>55: Shiloh AL, Eisen LA, Savel RH. Selective decontamination of the digestive</p>
<p>tract: what outcomes matter? Crit Care Med. 2010 May;38(5):1386-7. doi:</p>
<p>10.1097/CCM.0b013e3181da47d1. PMID: 20404637.</p>
<p> </p>
<p>56: Shiloh AL, Eisen LA. Ultrasound-guided arterial catheterization: a narrative</p>
<p>review. Intensive Care Med. 2010 Feb;36(2):214-21. doi:</p>
<p>10.1007/s00134-009-1699-6. Epub 2009 Oct 31. PMID: 19882140.</p>
<p> </p>
<p>57: Li M, Chen D, Shiloh A, Luo J, Nikolaev AY, Qin J, Gu W. Deubiquitination of</p>
<p>p53 by HAUSP is an important pathway for p53 stabilization. Nature. 2002 Apr</p>
<p>11;416(6881):648-53. doi: 10.1038/nature737. Epub 2002 Mar 31. PMID: 11923872.</p>
<p>Ariel L Shiloh, MD, is Director, Critical Care Consult Services, Professor, Medicine and Associate Professor, Neurology at Montefiore Einstein. Dr. Shiloh’s clinical interests include the early detection and treatment of critical illness, point-of-care ultrasonography for the evaluation of critical illness and advanced airway management.</p><p>After earning his Bachelor of Arts from Yeshiva University, Dr. Shiloh attended the Medical School for International Health at Ben Gurion University, Be’er Sheva, Israel, earning his Doctor of Medicine in 2005. He came to Montefiore for his postdoctoral training, completing his internship and residency in internal medicine in 2008, followed by his fellowship in critical care medicine in 2010.</p><p>Dr. Shiloh's research includes the clinical use of point-of-care ultrasonography in critical illness, improvement of airway management, and cardiopulmonary resuscitation. He has shared his work through peer-reviewed journals, invited presentations, books, abstracts and poster presentations at national conferences. He has also been a reviewer for several journals including <em>Chest</em>, the <em>American Journal of Critical Care</em> and the <em>European Journal of Anesthesiology</em>.</p><p>Dr. Shiloh is board certified in Internal Medicine, Critical Care Medicine and Neurocritical Care and Hospice & Palliative Medicine. He is a Fellow of the American College of Chest Physicians and a member of the Society of Critical Care Medicine. Dr. Shiloh has been recognized by the American College of Chest Physicians as a Distinguished CHEST Educator, among the top 5% of CHEST’s international faculty recognized for long-term contributions to the design and delivery of CHEST education</p>
Theresa M. Serra
Pediatric Medicine
<p class="MsoNormal">Theresa Serra, MD, joined the CHAM hospitalist division in 2014 after working as a pediatric hospitalist at New York Presbyterian/Lower Manhattan Hospital. Her interests include clinical research and medical education. She has conducted an IRB approved retrospective chart review examining readmission rates in pediatric patients diagnosed with osteomyelitis. Dr. Serra is currently developing a medical Spanish curriculum for faculty members in order to improve communication between patients, families and providers. Along with Courtney McNamara, MD, Dr. Serra is a co-leader of a multidisciplinary committee dedicated to standardizing and improving quality of care for patients hospitalized with the diagnosis of failure to thrive. Dr. Serra is also working on an initiative to identify vaccine delinquency in the inpatient setting through the use of SMART reports.</p> <p class="MsoNormal">Dr. Serra is also collaborating with Lindsey Douglas, MD, MSCR, in an IRB approved quality improvement (QI) project to improve transition-of-care communication between hospitalists and primary care providers and to facilitate the establishment of medical homes. Dr. Serra is also a member of a subcommittee that leads monthly journal clubs/case conferences for pediatric hospitalists.</p>
Elayna O. Rubens
<p>Elayna Rubens, MD, is Co-Director, Intraoperative Neurophysiologic Monitoring Service at Montefiore Einstein and Assistant Professor, Neurology at our Albert Einstein College of Medicine. Dr. Rubens’s primary clinical focus is performing intraoperative neurophysiologic monitoring to enhance the safety of surgeries that may affect the brain, spinal cord or peripheral nerves.</p><p>After obtaining her Bachelor of Science in biology and neurobiology from Cornell University in 1998, Dr. Rubens earned her Doctor of Medicine at Albert Einstein College of Medicine in 2003. Dr. Rubens completed her neurology residency at Beth Israel Deaconess Medical Center in 2007, where she was Chief Resident in her final year. She went on to complete a clinical neurophysiology fellowship at NewYork-Presbyterian-Weill Cornell Medical Center in 2009.</p><p>Dr. Rubens’s research focuses on enhancing neurophysiologic monitoring techniques to improve the safety of surgeries involving the nervous system. Her research also involves using clinical evoked potential testing and electroencephalography to improve neurologic patient care, particularly in the critical care setting. She has shared her work through numerous peer-reviewed publications and invited presentations.</p><p>Dr. Rubens is board certified by the American Board of Psychiatry and Neurology. She is a Fellow of the American Clinical Neurophysiology Society and member of the American Epilepsy Society and the American Academy of Neurology.</p>
Jillian L. Rosengard
<p class="MsoNormal" style="margin: 0in; font-size: 11pt; font-family: Arial, sans-serif; line-height: 16.8667px;">Jillian L. Rosengard, MD, is an attending physician and Associate Professor of Neurology at Montefiore Einstein. She specializes in the diagnosis and management of seizures and epilepsy. She has a particular interest in treating patients with intractable epilepsy and caring for women with epilepsy during their pregnancies, as well as medical education.</p>
<p class="MsoNormal" style="margin: 0in; font-size: 11pt; font-family: Arial, sans-serif; line-height: 16.8667px;"> </p>
<p class="MsoNormal" style="margin: 0in; font-size: 11pt; font-family: Arial, sans-serif; line-height: 16.8667px;">After obtaining her Bachelor of Arts at Harvard in 2008, Dr. Rosengard earned her Doctor of Medicine at Mount Sinai School of Medicine in 2012. She completed an internship in internal medicine at New York University Langone Medical Center in 2013 before completing her residency in neurology at Mount Sinai Medical Center in 2016, where she served as Chief Resident. Dr. Rosengard then completed a fellowship in clinical neurophysiology at Einstein in 2017.</p>
<p class="MsoNormal" style="margin: 0in; font-size: 11pt; font-family: Arial, sans-serif; line-height: 16.8667px;"> </p>
<p class="MsoNormal" style="margin: 0in; font-size: 11pt; font-family: Arial, sans-serif; line-height: 16.8667px;">Dr. Rosengard's research focuses on the impact of Covid-19 on patients with epilepsy as well as seizure prediction. She also participates in drug trials for new anti-seizure medications through Montefiore’s Clinical Research Center. She has been Principal Investigator and Co-Principal Investigator on several research projects, and her work has been published in numerous peer-reviewed journals and textbooks. Dr. Rosengard has given national presentations and has been a reviewer for scientific journals including <em>Neurology, Epilepsy & Behavior </em>and the<em> Journal of the Neurological Sciences.</em></p>
<p class="MsoNormal" style="margin: 0in; font-size: 11pt; font-family: Arial, sans-serif; line-height: 16.8667px;"><em> </em></p>
<p class="MsoNormal" style="margin: 0in; font-size: 11pt; font-family: Arial, sans-serif; line-height: 16.8667px;">Dr. Rosengard is board certified in Neurology and Epilepsy by the American Board of Psychiatry and Neurology. She is a member of the American Academy of Neurology and the American Epilepsy Society. In 2023, Dr. Rosengard was elected into the Leo M. Davidoff Society for outstanding achievement in the teaching of medical students, and she has been named a New York Super Doctors Rising Star for several years.</p>
Dr. Rosengard specializes in the diagnosis and management of seizures and epilepsy. She has a particular interest in treating women with epilepsy during their pregnancies as well as medical education.<br />
Dr. Rosengard's research focuses on the Covid-19 pandemic's inpatient on patients with epilepsy as well as seizure prediction. She also participates in drug trials for new anti-seizure medications through Montefiore Clinical Research Center.<br /><quillbot-extension-portal></quillbot-extension-portal>
Aparna V.R. Polavarapu
Puja Patel
<p>Puja Patel, MD, is an attending physician at Montefiore Einstein and Associate Professor, Neurology at our Albert Einstein College of Medicine. Dr. Patel's clinical focus is pediatric epilepsy, although she also sees patients with general pediatric neurological issues, including headaches, movement disorders, sleep concerns and developmental delay.</p><p>After obtaining her Bachelor of Arts in biology from Barnard College in 2005, Dr. Patel earned her Doctor of Medicine at the State University of New York Downstate Medical Center in 2009. She completed her internship and residency in pediatrics at NewYork-Presbyterian-Weill Cornell Medical Center in 2011. Following this, Dr. Patel came to Montefiore Einstein to continue her medical training, completing her pediatric neurology residency in 2014, a clinical neurophysiology fellowship in 2015 and a behavioral neurosciences fellowship in 2016.</p><p>Dr. Patel’s research focuses on clinical seizure prediction in the pediatric population. She has been co-investigator in several clinical drug trials investigating new anti-seizure medications. Her work has been shared through invited presentations and peer-reviewed journals, books, chapters, review articles and abstracts. She is a reviewer for scientific journals, including <em>Epilepsy Research, the Journal of Neurological Sciences and Pediatric Neurology</em>, among others.</p><p>Dr. Patel is board certified by the American Board of Psychiatry and Neurology in Neurology with special competence in Child Neurology. She is a member of the Child Neurology Society and the American Epilepsy Society.</p>
Raminder K. Parihar
Dr. Parihar is focused on expanding the DBS to improve the quality of life of patients with tremors, Parkinson's disease, and dystonia.
Dr. Parihar is interested in studying gait disorders and working to find advanced therapies to improve them.
<p><span id="docs-internal-guid-7b0a3849-df15-2ae7-5b01-dfa6f02928ba">1. Parihar, R; Mahoney, JR; Verghese, J. Relationship of Gait and Cognition in the Elderly. Curr Transl Geriatr Exp Gerontol Rep. 2013 Sep 1;2(3)</span></p>
<p>2. Bakshi K, Parihar R, Goswami SK, Walsh M, Friedman E, Wang HY. Prenatal cocaine exposure uncouples mGluR1 from Homer1 and Gq proteins. PLoS One. 2014 Mar 13;9(3):e91671. doi: 10.1371/journal.pone.0091671. eCollection 2014</p>
<p>3. <span id="docs-internal-guid-7b0a3849-df16-5152-5f73-3dd4cf8c18ee">Parihar R, Alterman R, Papavassiliou E, Tarsy D, Shih LC. Comparison of VIM and STN DBS for Parkinsonian Resting and Postural/Action Tremor. Tremor Other Hyperkinetic Mov. 2015 July 6;5: 321</span></p>
<p>4. <span id="docs-internal-guid-7b0a3849-df16-989c-b0c2-e768f5de3e9a">Tarsy, Daniel, and Raminder K. Parihar. Medication-Induced Movement Disorders. Cambridge, 2015. Print.</span></p>
<p>Raminder Parihar, MD, is Director, Neuromodulation at Montefiore Einstein and Assistant Professor, Neurology at our Albert Einstein College of Medicine. Dr. Parihar evaluates and treats patients with different movement disorders. She is also largely involved in evaluating patients for candidacy for deep brain stimulation (DBS) surgery for the treatment of different movement disorders and initiating and following up stimulation programming.</p><p>After obtaining her Bachelor of Science in biomedical sciences from the City College of New York in 2007, Dr. Parihar completed her Doctor of Medicine at Stony Brook University School of Medicine in 2009. She then came to Albert Einstein College of Medicine, where she completed an internship in medicine in 2010 and her residency in adult neurology in 2013, where she was Chief Resident in her final year. Dr. Parihar completed a fellowship in movement disorders at Harvard/Beth Israel Deaconess Medical Center in 2014.</p><p>Dr. Parihar’s research focuses on gait disorders and how they can predict cognitive impairment in patients with Parkinson's disease. She also studies the impact of deep brain stimulation in improving the quality of life in patients with movement disorders. Her work has been published in peer-reviewed book chapters and publications, and she has shared her work through lectures and platform and abstract presentations.</p><p>Dr. Parihar is a Diplomate of the American Board of Psychiatry and Neurology. She is a member of the American Academy of Neurology, the Movement Disorders Society and the American Medical Association (AMA). In 2023, Dr. Parihar was a recipient of the Marquis Who's Who in America Award.</p>