Acute Chest Syndrome

Allison M. Martin

Submitted by Anonymous (not verified) on
Full Name
Allison M. Martin
Profile Image URL
https://assets.montefioreeinstein.org/profiles/images/physphoto/Martin_Allison_MD_420x504.jpg
Type
Provider
Faculty
First Name
Allison
Last Name
Martin
NPI
1710200654
Faculty ID
15926
Clinical Terms
Employment Status
Full Time
Patient Type
Pediatric
Department
einstein-dept-pediatrics
einstein-dept-microbiology-immunology
Gender
Female
Email
allison.martin@einsteinmed.edu
Phone
718-839-7464
Titles
Type
Academic
Department
Department of Pediatrics
Department Link
Rank
Assistant Professor
Tags
me-patientcare-cancer-research-immunotherapy
Division
Pediatric Hematology-Oncology
Type
Academic
Department
Department of Microbiology & Immunology
Department Link
Rank
Assistant Professor
Type
Administrative
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.87885 40.88037)
Address Line 1
3415 Bainbridge Avenue
City
Bronx
State
NY
Zip
10467-2403
Location Title
The Children's Hospital at Montefiore
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8459022 40.8504961)
Building
Van Etten
Room
6A02
Address Line 1
Albert Einstein College of Medicine
Address Line 3
1225 Morris Park Avenue
City
Bronx
State
NY
Zip
10461
Location Title
Albert Einstein College of Medicine
Education and Trainings
Education Type Label
Medical Education
Education Institution
Jefferson Medical College
Education Type Label
Fellowship
Education Institution
National Institutes of Health
Education Type Label
Fellowship
Education Institution
Johns Hopkins University
Education Type Label
Residency
Education Institution
Childrens Hospital of Pittsburg / UPMC Health Sys
CHAM Provider
On
Professional Title
M.D.
EMR ID
102070
Biography

<p>Allison M. Martin, MD, is an attending physician at the Children&rsquo;s Hospital at Montefiore Einstein and Assistant Professor, Pediatrics, Microbiology and Immunology at our Albert Einstein College of Medicine. Dr. Martin&rsquo;s clinical focus centers on pediatric brain and spinal cord tumors.</p><p>After receiving her Bachelor of Arts in biology from Bryn Mawr College in 2001, Dr. Martin earned her Doctor of Medicine at Jefferson Medical College in 2007. She completed her pediatrics residency at the University of Pittsburgh in 2010, followed by a pediatric hematology/oncology fellowship at the Johns Hopkins University School of Medicine and the National Institutes of Health in 2013. Following this, Dr. Martin completed an additional fellowship in pediatric neuro-oncology at the Johns Hopkins University School of Medicine in 2014.</p><p>Dr. Martin&rsquo;s research focuses on high-risk group 3 and refractory medulloblastoma. Her research program focuses on uncovering new ways to harness the immune system to treat this disease. Her work has been shared through numerous peer-reviewed publications, abstracts, case reports and invited talks and panels. She has also been principal investigator and co-investigator on several funded research projects and is a reviewer for <em>Cancers</em>.</p><p>Dr. Martin is board certified in Pediatrics and Pediatric Hematology-Oncology. She is a member of the Children&rsquo;s Oncology Group (COG), the Cancer Therapy Evaluation Program (CTEP) and the Society of Immunotherapy and Cancer (SITC). In 2021, Dr. Martin received the Pediatric Hematology/Oncology Fellows Teaching Award from the Children&rsquo;s Hospital at Montefiore Einstein. She was named a &ldquo;Top Doctor&rdquo; by Castle Connolly in 2024.</p>

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Tania V. Marin Saquicela

Submitted by Anonymous (not verified) on
Full Name
Tania V. Marin Saquicela
Profile Image URL
https://assets.montefioreeinstein.org/profiles/images/default-profile-blue.svg
Type
Provider
Faculty
First Name
Tania
Last Name
Marin Saquicela
NPI
1316471758
Faculty ID
16725
CMO Specialties
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-medicine
Gender
Female
Provider Type
Primary Care
Email
tmarins@montefiore.org
Phone
718-920-5057
Titles
Type
Academic
Department
Department of Medicine
Department Link
Rank
Assistant Professor
Division
Hospital Medicine
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.88072 40.88002)
Address Line 1
111 East 210th Street
City
Bronx
State
NY
Zip
10461-2401
Location Title
Montefiore Medical Center
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8798833 40.8799447)
Address Line 1
Montefiore Medical Center
Address Line 3
111 East 210th Street
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore Medical Center
Education and Trainings
Education Type Label
Medical Education
Education Institution
University of Illinois College of Medicine
Education Type Label
Residency
Education Institution
Montefiore Medical Center
CHAM Provider
Off
Professional Title
M.D.
EMR ID
2577
Is Open Scheduling
Off

Ali Y. Mansour

Submitted by Anonymous (not verified) on
Full Name
Ali Y. Mansour
Profile Image URL
https://documentapi-fargate-documentbucket-15qi4tpdvnhlz.s3.amazonaws.com/218/707c8b40-470d-11ec-9350-298b34a4a389.jpg
Type
Provider
Faculty
First Name
Ali
Last Name
Mansour
NPI
1427279017
Faculty ID
17102
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-cardiothoracic-vascular
einstein-dept-medicine
Gender
Male
Email
amansour@montefiore.org
Phone
718-920-5864
Titles
Type
Academic
Department
Department of Cardiothoracic & Vascular Surgery
Rank
Assistant Professor
Type
Academic
Department
Department of Medicine
Department Link
Rank
Assistant Professor
Division
Pulmonary Medicine
Type
Clinical
Title
Medical Director, Advanced Pulmonary Failure and Lung Transplantation
Type
Clinical
Title
Assistant Professor
Type
Administrative
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.87862 40.88032)
Address Line 1
3400 Bainbridge Avenue
City
Bronx
State
NY
Zip
10467-240
Location Title
Montefiore Greene Medical Arts Pavilion
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8785732 40.879979)
Address Line 1
Montefiore Medical Center
Address Line 2
Medical Arts Pavilion
Address Line 3
3400 Bainbridge Avenue
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore Medical Center
Education and Trainings
Education Type Label
Medical Education
Education Institution
American University of Beirut
Education Type Label
Fellowship
Education Institution
Case Western Reserve University
Education Type Label
Fellowship
Education Institution
Baylor College of Med
Education Type Label
Residency
Education Institution
Kansas Univ Medical Center School of Medicine
CHAM Provider
Off
Professional Title
M.D.
Clinical Focus

C<span style="color:#525458;font-family:Arial, Helvetica, sans-serif;background-color:#ffffff;">linical focus includes interventional pulmonary medicine, interstitial lung disease, lung transplantation, vascular medicine and sleep medicine.</span><quillbot-extension-portal></quillbot-extension-portal>

Research Focus

<span style="color:#525458;font-family:Arial, Helvetica, sans-serif;background-color:#ffffff;">Dr. Mansour&rsquo;s research focuses on lung transplant and extracorporeal membrane oxygenation (ECMO) support during critical illnesses from severe lung disease.</span><quillbot-extension-portal></quillbot-extension-portal>

EMR ID
124228
Biography

<p style="padding-top:0px;color:#525458;font-family:Arial, Helvetica, sans-serif;background-color:#ffffff;">Ali Mansour, MD, is Medical Director, Advanced Pulmonary Failure and Lung Transplantation and Assistant Professor at Montefiore Einstein. His clinical focus includes interventional pulmonary medicine, interstitial lung disease, lung transplantation, vascular medicine and sleep medicine.</p><p style="padding-top:0px;color:#525458;font-family:Arial, Helvetica, sans-serif;background-color:#ffffff;">In 2000, Dr. Mansour received his Bachelor of Chemistry at the American University of Beirut. He continued his studies at this institution and received his Doctor of Medicine in 2004. Dr. Mansour began his postgraduate training in 2004 with a yearlong internship at the American University of Beirut Medical College. His training then took him to Kansas, where he completed an internship and residency in internal medicine in 2008 at the Kansas University Medical School. Following this, Dr. Mansour completed a fellowship in pulmonary and critical care that included advanced fellowship training in pulmonary transplantation at Baylor College of Medicine in 2011. In 2012, he completed a sleep fellowship at the University Hospital Case Western Medical Center. Dr. Mansour is board certified in echocardiography and vascular medicine and is accredited as an interventional pulmonologist.</p><p style="padding-top:0px;color:#525458;font-family:Arial, Helvetica, sans-serif;background-color:#ffffff;">Dr. Mansour&rsquo;s research focuses on lung transplant and extracorporeal membrane oxygenation (ECMO) support during critical illnesses from severe lung disease. He is also interested in lung cancer staging and advanced airway procedure to improve and prolong survival. More recently, he supervises numerous clinical studies and trials including novel therapies for SARS-CoV-2. His work has been published in a number of peer-reviewed publications, and he has been an invited speaker to numerous national oral presentations.</p><p style="padding-top:0px;color:#525458;font-family:Arial, Helvetica, sans-serif;background-color:#ffffff;">Dr. Mansour is a member of numerous professional societies, including the American Thoracic Society, the American Academy of Sleep Medicine and the American Association for Bronchology and Interventional Pulmonology. He is a fellow of the American College of Chest Physicians.</p>

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Keron Lezama

Submitted by Anonymous (not verified) on
Full Name
Keron Lezama
Profile Image URL
https://assets.montefioreeinstein.org/profiles/images/physphoto/Lezama_Keron_MD_420x504.jpg
Type
Provider
Faculty
First Name
Keron
Last Name
Lezama
NPI
1295098564
Faculty ID
15100
CMO Specialties
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-medicine
Gender
Male
Email
klezama@montefiore.org
Phone
718-904-2784
Titles
Type
Academic
Department
Department of Medicine
Department Link
Rank
Assistant Professor
Division
Hospital Medicine
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.845 40.85026)
Address Line 1
1825 Eastchester Road
City
Bronx
State
NY
Zip
10467-2404
Location Title
Montefiore Weiler Hospital
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8460414 40.8489787)
Address Line 1
Jack D. Weiler Hospital
Address Line 3
1825 Eastchester Road
City
Bronx
State
NY
Zip
10461
Location Title
Jack D. Weiler Hospital
Education and Trainings
Education Type Label
Medical Education
Education Institution
Columbia Univ College of Physicians and Surgeons
Education Type Label
Residency
Education Institution
Montefiore Medical Center
CHAM Provider
Off
Professional Title
M.D.
EMR ID
54791
Is Open Scheduling
Off

Adam S. Levy

Submitted by Anonymous (not verified) on
Full Name
Adam S. Levy
Profile Image URL
https://documentapi-fargate-documentbucket-15qi4tpdvnhlz.s3.amazonaws.com/218/79744f40-c947-11ed-8462-993dfb204153.jpg
Type
Provider
Faculty
First Name
Adam
Last Name
Levy
NPI
1710065974
Faculty ID
9837
Clinical Terms
Employment Status
Per Diem
Patient Type
Pediatric
Department
einstein-dept-pediatrics
Gender
Male
Email
adlevy@montefiore.org
Phone
718-741-2337
Titles
Type
Academic
Department
Department of Pediatrics
Department Link
Rank
Clinical Professor
Tags
me-patientcare-cancer-research-therapeutics
Division
Pediatric Hematology-Oncology
Type
Clinical
Title
Professor of Pediatrics
Type
Administrative
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.87885 40.88037)
Address Line 1
3415 Bainbridge Avenue
City
Bronx
State
NY
Zip
10467-2403
Location Title
The Children's Hospital at Montefiore
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.84154 40.84612)
Address Line 1
1250 Waters place
City
Bronx
State
NY
Zip
10461-2720
Location Title
Montefiore at 1250 Waters Place
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8791698 40.880273)
Room
968
Address Line 1
Montefiore Medical Center
Address Line 2
3415 Bainbridge Avenue
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore Medical Center
Education and Trainings
Education Type Label
Medical Education
Education Institution
New York University School of Medicine
Education Type Label
Fellowship
Education Institution
Memorial Sloan Kettering Cancer Center
Education Type Label
Residency
Education Institution
Mount Sinai School of Medicine
Professional Interests

<p>Dr. Levy, Director of Pediatric Neuro-Oncology at The Children&rsquo;s Hospital at Montefiore, was the principal investigator for the Children&rsquo;s Oncology Group, the nation's largest consortium of childhood cancer researchers, and currently leads an international clinical trial for children with recurrent brain tumors. Dr. Levy&rsquo;s clinical interests focus on brain tumors, particularly new drugs and treatment plans for children with brain tumors.</p>
<p>As Associate Professor of Clinical Pediatrics at Albert Einstein College of Medicine, Dr. Levy also has a strong interest in medical education. He is director of the pediatric hematology/oncology fellowship training program, and he is chair of the Committee on Graduate Medical Education.</p>
<p>After graduating from Cornell University, Dr. Levy received his medical degree from NYU School of Medicine. He was a Chief Resident in Pediatrics at Mount Sinai Medical Center, where he received the Department of Pediatrics Resident Clinician-Teacher Award. He then completed his fellowship and was Chief Fellow in Pediatric Hematology and Oncology at Memorial Sloan-Kettering Cancer Center and New York Hospital/Weill Cornell Medical Center, where he received the Charles Trobman Memorial Award.&nbsp; He was nominated Attending Physician of the Year in Pediatrics at NYU Medical Center before joining Montefiore and Einstein. In 2007 he received a Children&rsquo;s Tumor Foundation Humanitarian Award for his care of children with tumors associated with neurofibromatosis, and in 2011 he was elected to the Society for Pediatric Research.&nbsp;</p>
<p>&nbsp;</p>

CHAM Provider
Off
Professional Title
M.D.
Clinical Focus

<p>Brain and spinal cord tumors; pediatric solid tumors; neurofibromatosis</p>

Research Focus

<p>Dr. Levy practices general pediatric hematology-oncology with a focus on tumors of the brain and spine. Dr. Levy&rsquo;s current research interests concern the use of new drugs and treatment plans for children with cancer.</p>

EMR ID
4667
Biography

<p>Adam Levy, MD, is a Clinical Professor who works per diem at Montefiore Einstein in the trainee&rsquo;s clinic. He specializes in general pediatric hematology and oncology, with a focus on tumors of the brain and spine, solid tumors and tumors associated with neurofibromatosis.</p><p>After receiving his Bachelor of Science at Cornell University, Dr. Levy earned his Doctor of Medicine at New York University School of Medicine. Following this, he completed training in pediatrics at Mount Sinai Medical Center in New York and became Chief Resident. Dr. Levy then completed a pediatric hematology/oncology fellowship at Memorial Sloan-Kettering and New York Hospital/Weill Cornell Medical Center, where he served as Chief Fellow.</p><p>Dr. Levy&rsquo;s early research training in a transitional science laboratory focused on mechanisms and pathways explaining tumor cell chemotherapy resistance. He was the principal investigator for the Children&rsquo;s Oncology Group, the nation's largest consortium of childhood cancer researchers, and currently leads an international clinical trial for children with recurrent brain tumors. As a clinical investigator, his current research focuses on using new drugs and treatment plans for pediatric cancer patients. He has studied and published ways to improve clinical care of patients, mentorship in pediatric oncology, communication skills training and burnout amongst clinicians. He has been an invited presenter on these topics nationally.</p><p>Dr. Levy is a member of the Society for Pediatric Research, and his efforts have been recognized numerous times as a New York Magazine Top Doctor. He has also won many awards, including the Children&rsquo;s Tumor Foundation Humanitarian Award, The Davidoff Society Education Award and the Charles Trobman Memorial Award.</p>

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Leslie Lee

Submitted by Anonymous (not verified) on
Full Name
Leslie Lee
Profile Image URL
https://documentapi-fargate-documentbucket-15qi4tpdvnhlz.s3.amazonaws.com/218/b6b6c970-d504-11eb-9d97-7bd8ea6b93dc.jpg
Type
Provider
Faculty
First Name
Leslie
Last Name
Lee
NPI
1114269958
Faculty ID
15299
CMO Specialties
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-medicine
Gender
Female
Email
lelee@montefiore.org
Phone
718-904-3289
Titles
Type
Academic
Department
Department of Medicine
Department Link
Rank
Assistant Professor
Division
Hospital Medicine
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.845 40.85026)
Address Line 1
1825 Eastchester Road
City
Bronx
State
NY
Zip
10467-2404
Location Title
Montefiore Weiler Hospital
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8460414 40.8489787)
Address Line 1
Jack D. Weiler Hospital
Address Line 3
1825 Eastchester Road
City
Bronx
State
NY
Zip
10461
Location Title
Jack D. Weiler Hospital
Education and Trainings
Education Type Label
Medical Education
Education Institution
Weill Medical College of Cornell University
Education Type Label
Residency
Education Institution
Mount Sinai Hospital
CHAM Provider
Off
Professional Title
M.D.
EMR ID
88499
Is Open Scheduling
Off

Manoj Lal Karwa

Submitted by Anonymous (not verified) on
Full Name
Manoj Lal Karwa
Profile Image URL
https://assets.montefioreeinstein.org/profiles/images/default-profile-blue.svg
Type
Provider
Faculty
First Name
Manoj
Last Name
Karwa
NPI
1487735809
Faculty ID
6746
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-medicine
einstein-dept-neurology
Gender
Male
Email
mkarwa@montefiore.org
Phone
718-920-9784
Titles
Type
Academic
Department
Department of Medicine
Department Link
Rank
Associate Professor
Division
Critical Care
Type
Academic
Department
The Saul R. Korey Department of Neurology
Department Link
Rank
Assistant Professor
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.845 40.85026)
Address Line 1
1825 Eastchester Road
City
Bronx
State
NY
Zip
10467-2404
Location Title
Montefiore Weiler Hospital
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.861005 40.8939411)
Address Line 1
Montefiore Medical Center - Wakefield
Address Line 2
600 East 233rd Street
City
Bronx
State
NY
Zip
10466
Location Title
Montefiore Medical Center - Wakefield
Education and Trainings
Education Type Label
Medical Education
Education Institution
Mahadevappa Rampure
Education Type Label
Fellowship
Education Institution
Montefiore Medical Center
Education Type Label
Residency
Education Institution
Montefiore Medical Center
CHAM Provider
Off
Professional Title
M.B.,B.S.
EMR ID
4047
Is Open Scheduling
Off

Mahsa Kanzali

Submitted by Anonymous (not verified) on
Full Name
Mahsa Kanzali
Profile Image URL
https://assets.montefioreeinstein.org/profiles/images/default-profile-blue.svg
Type
Provider
Faculty
First Name
Mahsa
Last Name
Kanzali
NPI
1295122661
Faculty ID
18306
CMO Specialties
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-medicine
Gender
Female
Email
mkanzali@montefiore.org
Phone
718-579-2500
Titles
Type
Academic
Type
Academic
Department
Department of Medicine
Department Link
Rank
Assistant Professor
Division
Hospital Medicine
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8608 40.89439)
Address Line 1
600 East 233rd Street
City
New York
State
NY
Zip
10466-2604
Location Title
Montefiore Wakefield Campus
Is Primary
Off
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.86049 40.89552)
Address Line 1
4234 Bronx Boulevard
City
Bronx
State
NY
Zip
10466-2611
Location Title
Montefiore Medical Group-Wakefield Ambulatory Care Center
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8798833 40.8799447)
Address Line 1
Montefiore Medical Center
Address Line 3
111 East 210th Street
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore Medical Center
Education and Trainings
Education Type Label
Medical Education
Education Institution
Ross University School of Medicine
Education Type Label
Residency
Education Institution
Montefiore Medical Center
CHAM Provider
Off
Professional Title
M.D.
EMR ID
76958
Is Open Scheduling
Off

Betsy Herold

Submitted by Anonymous (not verified) on
Full Name
Betsy Herold
Profile Image URL
https://assets.montefioreeinstein.org/profiles/images/physphoto/Herold_Betsey_MD_420x504.jpg
Type
Provider
Faculty
Expert
First Name
Betsy
Last Name
Herold
NPI
1619938206
Faculty ID
10991
Clinical Terms
Employment Status
Full Time
Patient Type
Pediatric
Department
einstein-dept-pediatrics
einstein-dept-microbiology-immunology
einstein-dept-obstetrics-gynecology-womens-health
Gender
Female
Email
betsy.herold@einsteinmed.edu
Phone
718-839-7460
Titles
Type
Academic
Department
Department of Pediatrics
Department Link
Rank
Professor
Division
Pediatric Infectious Disease
Type
Academic
Department
Department of Microbiology & Immunology
Department Link
Rank
Professor
Type
Academic
Department
Department of Obstetrics & Gynecology and Women's Health
Department Link
Rank
Professor
Type
Clinical
Title
Chief, Division of Pediatric Infectious Disease
Type
Clinical
Title
Harold and Muriel Block Chair in Pediatrics
Type
Clinical
Title
Vice Chair, Research
Type
Clinical
Title
Director, Translational Prevention Research Center, Children's Hospital at Montefiore
Type
Clinical
Title
Professor of Pediatrics, Albert Einstein College of Medicine
Type
Administrative
Title
Harold and Muriel Block Chair in Pediatrics
Type
Administrative
Title
Vice Chair for Research, Department of Pediatrics
Type
Administrative
Title
Chief, Division of Pediatric Infectious Diseases, Department of Pediatrics
Type
Administrative
Title
Director, Translational Prevention Research Center
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.87885 40.88037)
Address Line 1
3415 Bainbridge Avenue
City
Bronx
State
NY
Zip
10467-2403
Location Title
The Children's Hospital at Montefiore
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8459022 40.8504961)
Building
Van Etten
Room
6A04A
Address Line 1
Albert Einstein College of Medicine
Address Line 3
1225 Morris Park Avenue
City
Bronx
State
NY
Zip
10461
Location Title
Albert Einstein College of Medicine
Education and Trainings
Education Type Label
Medical Education
Education Institution
University of Pennsylvania School of Dental Med
Education Type Label
Fellowship
Education Institution
Northwestern University/ Children's Memorial Hosp.
Education Type Label
Residency
Education Institution
Northwestern University/ Children's Memorial Hosp.
Professional Interests

<p><strong>Betsy Herold, M.D.</strong> directs a basic and translational research program, which focuses on virus host interactions. Projects in the lab include studies designed to identify the cellular signaling pathways that herpes simplex viruses (HSV) usurp to promote viral entry and infection. The lab uncovered a previously unappreciated paradigm associated with activation of phospholipid scramblases, which are known to catalyze the movement of phosphatidylserine lipids between the inner and outer leaflet of the plasma membrane. Surprisingly, they found that the exofacial movement of phospholipids is associated with concomitant translocation of intracellular proteins, including the master kinase Akt to the outside, where Akt becomes phosphorylated to activate an &ldquo;outside-inside&rdquo; signaling cascade that promotes viral entry. This pathway is also usurped by SARS-CoV-2 and is important for cellular processes including apoptosis. In collaboration with the Almo lab, they have engineered cell impermeable kinase inhibitors. These compounds block viral entry and prevent induction of apoptosis by select TNF ligands.</p>
<p> Serendipitously, in studying this signaling pathway, the lab identified a novel candidate vaccine for the prevention and treatment of HSV infections.  Most efforts to develop a vaccine have focused on neutralizing antibodies that target HSV glycoprotein D (gD), but all of these have failed in clinical trials. Instead, the lab (in collaboration with the Jacobs lab), engineered a virus completely deleted in gD. Glycoprotein D is required for viral entry and cell-to-cell spread, thus the deletion virus (DgD-2) is restricted a single cycle and will not spread. This candidate vaccine elicits T cell responses and high titer, polyfunctional antibodies that protect through antibody-dependent cell mediated cytotoxicity (ADCC). The vaccine prevents the establishment of latency in mice and is significantly more protective in multiple small animal models than prior vaccines that have failed in clinical trials. The lab has subsequently isolated monoclonal antibodies (mAbs) that have this protective ADCC activity and both the vaccine and the mAbs are being advanced for preclinical development.  Studies to understand why this vaccine elicits ADCC-mediating antibodies whereas gD vaccines and primary HSV infection only elicit neutralizing antibodies led to the identification of a key role for TNFRSF14 (aka HVEM) in generating and mediating ADCC responses. HVEM is an immune cell surface protein that functions in signal transduction pathways that regulate inflammatory or inhibitory immune responses but its role in shaping the B cell repertoire and in providing a second signal for ADCC had not been previously described and has implications for vaccine development and oncolytic therapies. </p>
<p> The third major area of basic research involves defining the molecular mechanisms underlying the HIV-HSV syndemic. Epidemiological studies have consistently demonstrated that being HSV seropositive is associated with an increased risk for HIV acquisition, replication, higher plasma viral loads and more frequent episodes of HIV reactivation.  Using primary cells from patients and HIV latently infected cell lines, the lab has identified several mechanisms by which HSV promotes HIV latency reversal and replication including upregulation of the noncoding RNA, <em>Malat1</em>, and downregulation of IL-32. Defining these pathways may lead to identification of new strategies to &ldquo;shock and kill&rdquo; or &ldquo;block and lock&rdquo; HIV.</p>
<p> Clinical studies include prevention of infectious disease complications in transplantation. Members of the research group are involved in studies to optimize pre-emptive prophylaxis for CMV and EBV, vaccine responses in transplantation recipients, and others</p>

Research Areas
Herpes simplex virus (HSV) infection; synergy between HSV and HIV; microbicide development; genital tract mucosal immunity
Areas of Expertise
Antibiotic resistance
Antimicrobial resistance
Community-acquired MRSA (Methicillin-resistant Staphylococcus aureus)
HSV (herpes simplex virus)
Transplant infectious diseases
Expert Summary

<div>Dr. Herold directs a translational research program focused on the interactions between viruses and their host and using that knowledge to develop novel treatment and prevention strategies. Through her basic science studies, Dr. Herold has developed a unique candidate vaccine to prevent herpes simplex virus (HSV) infections, which is being advanced for phase I clinical trials. Studies of this vaccine uncovered a previously unappreciated immune evasion strategy; this knowledge may accelerate the development of drugs to bolster vaccine and monoclonal antibody efficacy against a range of pathogens.&nbsp;</div>
<div><span style="white-space: pre;"> </span>&nbsp;</div>
<div>Her studies on HIV focus on the development of safe and effective pre-exposure prophylactic strategies and on investigating how HSV interacts with HIV to reactivate HIV. Dr. Herold's team also has discovered a previously unrecognized phenomenon in cell biology in which HSV and other viruses activate a mechanism that helps them gain entry and infect healthy cells. This provides a novel target for the development of new antiviral drugs.&nbsp;<br /><br /></div>
<div>Most recently, her lab has studied why children respond differently and are relatively protected from severe COVID-19. Defining the differences in the immune response in children compared to adults will provide insights into protective immunity against this virus and future pandemic viruses.&nbsp;<br /><br /></div>
<div>Her clinical research focuses on infections in pediatric transplant recipients. Dr. Herold helped established and is co-chair of the Pediatric Infectious Diseases Society Transplant Research Network (PIDTRAN), which supports and promotes projects to prevent and treat infectious diseases among child transplant recipients. Dr. Herold has served on the Office of AIDS Research Advisory Council and on the Pediatric Infectious Diseases Society Council. She has been continuously funded by the NIH since 1989. Dr. Herold has over 180 publications in peer-reviewed journals and has presented her work internationally.</div>

CHAM Provider
On
Professional Title
M.D.
Clinical Focus

Pediatric Infectious Diseases.

Research Focus

Prevention and treatment of infections in solid and stem cell transplant patients and other immunocompromised patients.

Lab Website Link
EMR ID
4968
Biography

<p>Betsy Herold, MD, is Chief of the Division of Pediatric Infectious Diseases and Vice Chair for Research at Children's Hospital at Montefiore. Dr. Herold is also a Professor of Pediatrics, Microbiology &amp; Immunology, and Obstetrics &amp; Gynecology and Women's Health at our Albert Einstein College of Medicine. She specializes in pediatric infectious diseases. </p><p>Dr. Herold received her Bachelor of Arts in Biology in 1978 from Brown University and went on to receive her Doctor of Medicine from the University of Pennsylvania Medical School in 1982. Dr. Herold completed an internship and residency in pediatrics at Children's Memorial Hospital, where she became a Chief Resident in 1985. She then began a fellowship in research at Hagedorn Research Laboratory in Gentofte, Denmark. In 1987, Dr. Herold began a fellowship in pediatric infectious diseases at Children's Memorial Hospital, followed by a Research Associate/Postdoctoral Virology Fellowship in the Department of Microbiology and Immunology at Northwestern University in Chicago. </p><p>Dr. Herold's clinical research focuses on the prevention and treatment of infections in solid and stem cell transplant patients and other immunocompromised patients. Dr. Herold has also been involved in research in Kawasaki disease and the emergence of methicillin-resistant staphylococcus aureus (MRSA) in the community. Dr. Herold directs a basic and translational research program on the prevention of herpes simplex virus (HSV) and HIV infections through the development of vaccines and novel antivirals. The current major focus of her lab is on a novel, paradigm-shifting, single-cycle vaccine to prevent HSV-1 and HSV-2. She has been continuously funded by the NIH since 1989. Dr. Herold has over 150 peer reviewed publications in peer-reviewed journals and has presented her work internationally. </p><p>In 2012, Dr. Herold received the Clinical Science Faculty Mentor Award from the Albert Einstein College of Medicine. She has also been awarded the Henry and Jacob Lowenberg Prize in Pediatrics and the Pediatric Infectious Disease Young Investigator Award. Dr. Herold is board certified by the American Board of Pediatrics in Pediatrics and in Pediatric Infectious Diseases. </p>

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Michelle Ng Gong

Submitted by Anonymous (not verified) on
Full Name
Michelle Ng Gong
Profile Image URL
https://documentapi-fargate-documentbucket-15qi4tpdvnhlz.s3.amazonaws.com/218/328d3b60-bf8b-11ee-b89e-33007638942c.jpg
Type
Provider
Faculty
First Name
Michelle
Last Name
Gong
NPI
1114946233
Faculty ID
11976
Clinical Terms
Employment Status
Full Time
Patient Type
Adult
Department
einstein-dept-medicine
einstein-dept-epidemiology-population-health
Languages
Cantonese
Gender
Female
Email
mgong@montefiore.org
Phone
718-920-2956
Titles
Type
Academic
Department
Department of Medicine
Department Link
Rank
Professor
Division
Critical Care
Type
Academic
Department
Department of Epidemiology & Population Health
Department Link
Rank
Professor
Division
Epidemiology
Type
Clinical
Title
Chief of Critical Care Medicine, Associate Chief of Academic Affairs, and Director of Critical Care Research at Montefiore
Type
Clinical
Title
Chief, Department of Medicine Division of Pulmonary Medicine
Type
Clinical
Title
Professor of Medicine (Critical Care) and Epidemiology and Population Health at Albert Einstein College of Medicine
Type
Administrative
Title
Chief, Division of Critical Care, Department of Medicine
Type
Administrative
Title
Chief, Division of Pulmonary Medicine, Department of Medicine
Type
Administrative
Title
Director, Critical Care Research, Department of Medicine
Type
Administrative
Title
Interim Chair, Department of Medicine
Tags
einstein-dept-medicine-leadership
Locations
Is Primary
On
Type
Clinical
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.88072 40.88002)
Address Line 1
111 East 210th Street
City
Bronx
State
NY
Zip
10461-2401
Location Title
Montefiore Medical Center
Is Primary
Off
Type
Academic
Location (Address, State, City, Zip)
Not used, will be deleted
Coordinates
POINT (-73.8798833 40.8799447)
Building
Gold Zone
Address Line 1
Montefiore Medical Center
Address Line 3
111 East 210th Street
City
Bronx
State
NY
Zip
10467
Location Title
Montefiore Medical Center
Education and Trainings
Education Type Label
Medical Education
Education Institution
Yale University School of Medicine
Education Type Label
Fellowship
Education Institution
Brigham & Women's Hosp. Boston
Education Type Label
Residency
Education Institution
Beth Israel Deaconess Hosp - East Campus
Professional Interests

<p>Dr. Gong is the Chief of Critical Care Medicine, Chief of Pulmonary Medicine, and Director of Critical Care Research at Montefiore Medical Center and Professor in Medicine and in Epidemiology and Population Health at Albert Einstein College of Medicine. After receiving an engineering degree at the University of Pennsylvania, Dr. Gong went on to earn a medical degree at the Yale University School of Medicine. She then completed her postdoctoral training at the Beth Israel Hospital in medicine and at the Brigham and Women&rsquo;s Hospital in the Harvard Combined Program in Pulmonary and Critical Care Medicine. She also studied at the Harvard School of Public Health, receiving her Master&rsquo;s degree in Clinical Epidemiology. Prior to coming to Albert Einstein College of Medicine and Montefiore Medical Center, she was Assistant Professor of Medicine in the division of Pulmonary, Critical Care and Sleep Medicine at the Mount Sinai School of Medicine.&nbsp; She joined the Einstein/Montefiore faculty in July 2009.</p>
<p>Dr. Gong is recognized nationally and internationally for her expertise in critical care delivery and management of acute respiratory failure and acute respiratory distress syndrome (ARDS).&nbsp; She has spent her career on improving outcomes in patients along the entire continuum of critical illness from its development to its progression and recovery with an overall focus on the prediction and prevention of acute organ failure and their complications.&nbsp; Nationally, she is a well-respected clinical researcher and trialist in acute injury and critical illness.&nbsp; &nbsp;Continuously funded by the NIH for over 20 years for her work, her research ranges from COVID-19 and ARDS to prevention of delirium, treatment of severe influenza, big data and predictive analytics in risk prediction, and effective clinical decision support systems. Her research has been published in the New England Journal of Medicine and JAMA.&nbsp; She has also been funded by the AHRQ on clinical decision making in ARDS&nbsp; and by the NHLBI for the Montefiore-Sinai Clinical Center for the PETAL Clinical Trials Network focused on the prevention and early treatment of ARDS.</p>
<p>A model clinician-researcher, her scientific projects influence her clinical care, and her patients motivates her research. So it is not surprising that some of her proudest achievements have occurred within her clinical work to improve outcomes for patients within Montefiore.&nbsp; This has included process improvement projects such as the implementation of sedation and delirium protocols and early mobilization in the medical intensive care unit that has reduced duration of mechanical ventilation, length of stay, hospital costs and ICU complications.&nbsp; She has also worked on the incorporation of artificial intelligence to help identify patients at increased risk of poor outcomes at Montefiore and evaluation of clinical decision support systems. She has co-authored the Surviving Sepsis Guidelines on management of patients with COVID-19, published in Intensive Care Medicine.&nbsp;</p>
<p>Dr. Gong is a well-regarded leader in the field of pulmonary and critical care medicine.&nbsp; She is a graduate of the prestigious Executive Leadership in Academic Medicine Fellowship and was the former or current chair of the Critical Care Planning Committee and the Critical Care Assembly for the American Thoracic Society. She is also on the Discovery Oversight Committee that helps plan the direction and agenda for the clinical trials initiative of the Society of Critical Care Medicine.&nbsp; Dr. Gong was awarded the Gotham Icon Award for Champions and Change Makers of New York City by the Museum of the City of New York in 2020. Given her expertise, she has been named to multiple panels to develop clinical practice guidelines, including the American College of Chest Physicians and the American Thoracic Society clinical practice guidelines for liberation from mechanical ventilation and the Surviving Sepsis Campaign guidelines for management of severe COVID-19 in 2020.&nbsp; In these leadership positions, she has had the fortune and privilege to mentor residents, fellows and junior investigators both within and beyond Montefiore into productive, academic careers in medicine.</p>

CHAM Provider
Off
Professional Title
M.D.
M.S.
Clinical Focus

Dr. Gong&rsquo;s clinical focus is on critical care delivery, predictive analytics, and process improvements, such as the implementation of sedation and delirium protocols and early mobilization in the medical intensive care unit, which has reduced the duration of mechanical ventilation, length of stay, hospital costs, and ICU complications.

Research Focus

Current research ranges from acute respiratory distress syndrome to prevention of delirium, treatment of severe influenza, big data and predictive analysis in risk prediction, and effective clinical decision support systems.

EMR ID
5230
Biography

<p>Michelle N. Gong, MD, MS, is a Professor of Medicine and Epidemiology and Population Health at Albert Einstein College of Medicine. She is also the Chief of Critical Care Medicine, Associate Chief of Academic Affairs, and Director of Critical Care Research at Montefiore. Dr. Gong&rsquo;s clinical focus is on critical care delivery, predictive analytics, and process improvements, such as the implementation of sedation and delirium protocols and early mobilization in the medical intensive care unit, which has reduced the duration of mechanical ventilation, length of stay, hospital costs, and ICU complications. She joined the Einstein/Montefiore faculty in July 2009.</p> <p>Dr. Gong received an Engineering degree at the University of Pennsylvania. She then went on to earn her Doctor of Medicine at the Yale University School of Medicine. She completed her postdoctoral training at the Beth Israel Hospital in medicine and at the Brigham and Women&rsquo;s Hospital in the Harvard Combined Program in Pulmonary and Critical Care Medicine. Dr. Gong studied at the Harvard School of Public Health, receiving her Master&rsquo;s Degree in Clinical Epidemiology. </p>Dr. Gong has spent her career improving outcomes in patients along the entire continuum of critical illness, from its development to progression and recovery, with an overall focus on the prediction and prevention of acute organ failure and its complications. Her current research ranges from acute respiratory distress syndrome to prevention of delirium, treatment of severe influenza, big data and predictive analysis in risk prediction, and effective clinical decision support systems. Under her leadership, Montefiore/Einstein was selected as a clinical center for the NHLBI Prevention and Early Treatment of Acute Lung Injury (PETAL) Clinical Trials Network which represents the first representation of a medical center from the New York and the tri-state area. Collaborating with the research informatics and healthcare industries, Dr. Gong has fostered the application of informatic approaches to drive improvement in healthcare delivery and research.</p><p>In 2013, Dr. Gong received the ATS Innovation in Fellowship Education Award. She is board certified by the American Board of Internal Medicine in Internal Medicine, Critical Care Medicine, Palliative Care Medicine, and Pulmonary Medicine. </p>

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