barzali

Institute for Aging Research

Publications

  1. N. Barzilai, G. Atzmon, C.A. Derby, J.M. Bauman, and R.B. Lipton, A genotype of exceptional longevity is associated with preservation of cognitive function (2006). Neurology; 67: 2170
  2. Martin GM, Bergman A, Barzilai N. Genetic determinants of human health span and life span: progress and new  opportunities. PLoS Genet. 2007 Jul;3(7):e125. Review.
  3. Iwata N, Zhang J, Atzmon G, Leanza S, Cho J, Chomyn A, Burk RD, Barzilai N, Attardi G. Aging-related occurrence in Ashkenazi Jews of leukocyte heteroplasmic mtDNA mutation adjacent to replication origin frequently remodeled  in Italian centenarians. Mitochondrion. 2007 Jul;7(4):267-72.
  4. Bergman A, Atzmon G, Ye K, MacCarthy T, Barzilai N. Buffering mechanisms in aging: a systems approach toward uncovering the genetic component of aging. PLoS Comput Biol. 2007
  5. Suh Y, Atzmon G, Cho MO, Hwang D, Liu B, Leahy DJ, Barzilai N, Cohen P.  Functionally significant insulin-like growth factor-I receptor mutations in centenarians. PNAS; Epub March 3rd 2008.
  6. Atzmon G, Pollin TI, Crandall J, Tanner K, Schechter CB, Scherer PE, Rincon M, Siegel G, Katz M, Lipton RB, Shuldiner AR,  Barzilai N. Adiponectin levels and genotype: a potential regulator of life span in humans. J Gerontol A Biol Sci Med Sci. 2008 May;63(5):447-53.
  7. Atzmon G, Barzilai N, Hollowell JG, Surks MI, Gabriely I.. Extreme longevity is associated with increased serum thyrotropin.  J Clin Endocrinol Metab. 2009 Apr;94(4):1251-4. Epub 2009 Jan 21.
  8. J. Shlush LI, Atzmon G, Weisshof R, Behar D, Yudkovsky G, Barzilai N, Skorecki K. . Ashkenazi Jewish centenarians do not demonstrate enrichment in mitochondrial haplogroup PLoS ONE. 2008;3(10):e3425.
  9. Atzmon G, Barzilai N, Hollowell JG, Surks MI, Gabriely I. Genetic Predisposition to Elevated Serum Thyrotropin is Associated with Exceptional Longevity. J Clin Endocrinol Metab 2009 Oct 16.
  10. West G, and Bergman A, 2009, “Towards a Systems Biology Framework for Understanding Aging and Healthspan”, Journal of Gerontology: Series A 2009 Feb;64(2)
  11. Walston JD, Matteini AM, Nievergelt C, Lange LA, Fallin DM, Barzilai N, Ziv E, Pawlikowska L, Kwok P, Cummings SR, Kooperberg C, Lacroix A, Tracy RP, Atzmon G, Lange EM, Reiner APInflammation And Stress-Related Candidate Genes, Plasma Interleukin-6 Levels, And Longevity In Older Adults. Exp Gerontol. 2009 Feb 25.
  12. Pawlikowska L, Hu D, Huntsman S, Sung A, Chu C, Chen J, Joyner AH, Schork NJ, Hsueh WC, Reiner AP, Psaty BM, Atzmon G, Barzilai N, Cummings SR, Browner WS, Kwok PY, Ziv E; Study of Osteoporotic Fractures. Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity.  Aging Cell. 2009 Aug;8(4):460-72. Epub 2009 May 31.
  13. Muzumdar RH, Huffman DM, Atzmon G, Buettner C, Cobb LJ, Fishman S, Budagov T, Cui L, Einstein FH, Poduval A, Hwang D, Barzilai N, Cohen P. Humanin: a novel central regulator of peripheral insulin action. PLoS One. 2009 Jul 22;4(7):e6334.
  14. Atzmon G, Cawthon RM, Suh Y, Budagov T, Katz M, Yang X, Siegel G, Bergman A, and Barzilai N.  Heritability of Long Telomeres in Families with Exceptional Longevity. In Press PNAS
  15. Conneel K, Capell BC , Erdos MR, Sebastiani P, Timofeev N, Terry DF , Baldwin CT, Budagov T, Atzmon G, Barzalai N, Thomas GA, Puca AA,. Perls TT, Geesaman BJ, Boehnke M, ,Collins F. Human longevity and common variations in the LMNA gene. In Press PNAS
  16. Lipton, R.B., Sanders, A.E., Wang, C., Katz, M., Derby, C.A., Barzilai, N., Ozelius, L.  Cholesteryl Ester Transfer Protein (CETP) polymorphism is associated with a reduced rate of memory decline and reduced incidence of dementia:).  Submitted after revision to JAMA, 2009.
  17. Barzilai N, Gabriely I, Gabriely M, Iankowitz N, Sorkin JD. “Offspring of centenarians have a favorable lipid profile.” J Am Geriat Soc. 2001: 49:76-79
  18. Atzmon G, Gabriely I, Greiner W, Davidson D, Barzilai N: “Plasma HDL levels highly correlate with cognitive function in exceptional longevity.” J. Gerontol. A Biol. Sci. Med. Sci. 2002: 57:M712-5
  19. Barzilai N, Atzmon G, Schechter C., Schaefer E., Cupples AL, Lipton R, Cheng S, Shuldiner AR. “Unique lipoprotein phenoytype and genotype associated with exceptional longevity.” JAMA 2003: 290:2030-40
  20. Atzmon G, Schechter C, Greiner W, Davidson D, Rennert G, Barzilai N. “Clinical phenotype of families with longevity.” J. Am. Geriat. Soc. 2004: 52:274-277
  21. Atzmon G, Rincon M, Schechter C, Shuldiner An, Lipton R, Bergman A, Barzilai N: Lipoprotein Genotype and Conserved Pathway for Exceptional Longevity in Humans. PLoS Biol 2006 Apr;4(4):e113